Alfred Zippelius Selected Research

Lectins

3/2024	Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2.
10/2020	Tumor-associated carbohydrates and immunomodulatory lectins as targets for cancer immunotherapy.

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Alfred Zippelius Research Topics

Disease

90	Neoplasms (Cancer) 03/2024 - 01/2002
28	Melanoma (Melanoma, Malignant) 04/2024 - 07/2002
18	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 01/2013
7	Breast Neoplasms (Breast Cancer) 01/2023 - 03/2004
7	Neoplasm Metastasis (Metastasis) 01/2021 - 04/2004
5	Lung Neoplasms (Lung Cancer) 03/2024 - 01/2015
5	Pneumonia (Pneumonitis) 01/2024 - 12/2015
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2023 - 01/2015
3	Disease Progression 11/2022 - 10/2014
2	Myocarditis (Carditis) 01/2024 - 01/2015
2	Hodgkin Disease (Hodgkin's Disease) 01/2023 - 11/2019
2	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 11/2018
2	Tertiary Lymphoid Structures 01/2021 - 01/2018
2	Carcinogenesis 10/2020 - 10/2019
2	Colorectal Neoplasms (Colorectal Cancer) 11/2019 - 10/2019
2	Virus Diseases (Viral Diseases) 01/2018 - 01/2017
2	Adenocarcinoma 01/2017 - 05/2016
2	Inflammation (Inflammations) 01/2016 - 11/2015
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2015 - 01/2013
1	Infections 05/2024
1	Hepatitis 01/2024
1	Colitis 01/2024
1	Diabetes Mellitus 01/2023
1	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2023
1	Optic Nerve Diseases (Optic Neuropathy) 01/2023

Drug/Important Bio-Agent (IBA)

17	AntigensIBA 05/2024 - 01/2002
17	Immune Checkpoint InhibitorsIBA 01/2024 - 01/2016
12	AntibodiesIBA 01/2022 - 10/2002
10	Peptides (Polypeptides)IBA 12/2018 - 07/2002
9	Proteins (Proteins, Gene)FDA Link 03/2021 - 09/2004
8	LigandsIBA 11/2022 - 10/2010
8	MART-1 AntigenIBA 10/2010 - 07/2002
7	IpilimumabIBA 02/2024 - 01/2015
7	Neoplasm Antigens (Tumor Antigens)IBA 12/2019 - 10/2002
6	NivolumabIBA 01/2023 - 01/2015
6	CytokinesIBA 09/2022 - 02/2016
6	Messenger RNA (mRNA)IBA 12/2019 - 06/2007
6	VaccinesIBA 01/2018 - 01/2002
5	Sialic Acid Binding Immunoglobulin-like LectinsIBA 03/2024 - 11/2018
5	Biomarkers (Surrogate Marker)IBA 02/2024 - 01/2020
4	pembrolizumabIBA 01/2023 - 01/2015
4	Immunoconjugates (Immunoconjugate)IBA 10/2019 - 08/2014
3	N-Acetylneuraminic Acid (Sialic Acid)IBA 03/2024 - 10/2020
3	Polysaccharides (Glycans)IBA 03/2024 - 10/2020
3	Bispecific AntibodiesIBA 11/2022 - 02/2016
3	Programmed Cell Death 1 ReceptorIBA 11/2022 - 01/2016
3	RNA (Ribonucleic Acid)IBA 11/2022 - 12/2018
3	Interleukin-12 (IL 12)IBA 09/2022 - 12/2018
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 09/2015
3	EpitopesIBA 03/2009 - 07/2002
3	Differentiation AntigensIBA 02/2007 - 04/2004
2	LectinsIBA 03/2024 - 10/2020
2	Immunoglobulins (Immunoglobulin)IBA 03/2024 - 11/2022
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2024 - 01/2015
2	Infliximab (Remicade)FDA Link 01/2024 - 01/2018
2	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2024 - 01/2023
2	Dinoprostone (PGE2)FDA Link 01/2023 - 01/2023
2	AutoantibodiesIBA 01/2023 - 01/2017
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2022 - 01/2019
2	Cisplatin (Platino)FDA LinkGeneric 10/2021 - 09/2015
2	Interleukin-2 (IL2)IBA 03/2021 - 10/2010
2	InterferonsIBA 01/2021 - 01/2019
2	AutoantigensIBA 01/2021 - 05/2003
2	Antisense OligonucleotidesIBA 01/2020 - 12/2019
2	Blocking AntibodiesIBA 11/2019 - 03/2015
2	Monoclonal AntibodiesIBA 08/2019 - 11/2018
2	carbonic anhydrase XIIIBA 08/2019 - 12/2015
2	SurvivinIBA 05/2019 - 01/2019
2	Uncoupling Protein 2IBA 04/2019 - 01/2019
2	Ado-Trastuzumab EmtansineIBA 01/2019 - 11/2015
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019 - 09/2017
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2018 - 04/2004
2	PlatinumIBA 01/2018 - 01/2017
2	Pemetrexed (MTA)FDA Link 01/2017 - 09/2015
2	Bevacizumab (Avastin)FDA Link 01/2017 - 09/2015
2	Drug CombinationsIBA 01/2016 - 09/2015
2	VemurafenibIBA 01/2015 - 05/2013
2	HLA-A2 Antigen (HLA A2 Antigen)IBA 10/2010 - 05/2004
2	HLA-A*02:01 antigenIBA 12/2006 - 02/2003
1	Sialic AcidsIBA 03/2024
1	Abatacept (Orencia)FDA Link 01/2024
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2024
1	vedolizumabIBA 01/2024
1	ruxolitinibIBA 01/2024
1	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 01/2024
1	Acetylcysteine (Siran)FDA LinkGeneric 01/2023
1	pegademase bovine (pegADA)FDA Link 01/2023
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2023
1	cyclopropapyrroloindoleIBA 01/2023
1	SteroidsIBA 01/2023
1	AlpelisibIBA 01/2023
1	Chimeric Antigen ReceptorsIBA 01/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023
1	ProstaglandinsIBA 01/2023

Therapy/Procedure

38	Immunotherapy 02/2024 - 01/2002
33	Therapeutics 01/2024 - 08/2003
7	Drug Therapy (Chemotherapy) 10/2021 - 01/2013
6	Radiotherapy 01/2019 - 01/2014
3	Neoadjuvant Therapy 10/2021 - 09/2015
1	Cell- and Tissue-Based Therapy (Cell Therapy) 04/2024