Zhong Zhao Selected Research

Alzheimer Disease (Alzheimer's Disease)

1/2023	Cooperation between neurovascular dysfunction and Aβ in Alzheimer's disease.
1/2013	Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease.
11/2007	Valsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease.
6/2007	Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.
8/2006	Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.
12/2005	Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.
4/2005	Expression of tau reduces secretion of Abeta without altering the amyloid precursor protein content in CHOsw cells.
5/2004	Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
12/2003	Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity.
1/2002	Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Zhong Zhao Research Topics

Disease

10	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 01/2002
4	Infections 01/2015 - 12/2012
3	Cognitive Dysfunction 01/2024 - 06/2007
3	Neoplasms (Cancer) 01/2022 - 04/2003
3	Tetraploidy 01/2017 - 01/2014
3	Amyloidosis 01/2007 - 12/2003
3	Insulin Resistance 05/2006 - 05/2004
3	Diabetes Mellitus 05/2006 - 05/2004
2	Atherosclerosis 05/2024 - 01/2020
2	Ischemic Stroke 05/2024 - 11/2013
2	Stroke (Strokes) 01/2022 - 11/2013
2	Dementia (Dementias) 01/2016 - 12/2005
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2008 - 04/2006
2	Amyloid Plaque 12/2005 - 01/2002
1	Cerebral Small Vessel Diseases 01/2024
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2024
1	Movement Disorders (Movement Disorder) 01/2024
1	Bacterial Infections (Bacterial Infection) 11/2023
1	Glioma (Gliomas) 01/2022
1	Anxiety Disorders (Anxiety Disorder) 12/2021
1	Pain (Aches) 12/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 12/2021
1	Death (Near-Death Experience) 11/2020
1	Intracranial Arteriosclerosis (Cerebral Atherosclerosis) 01/2020
1	Cerebral Infarction 01/2020
1	Infarction (Infarctions) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 07/2018
1	Inflammation (Inflammations) 01/2018
1	Rubella (German Measles) 01/2018
1	Ischemia 09/2017
1	Brain Injuries (Brain Injury) 09/2017
1	Genetic Predisposition to Disease (Genetic Predisposition) 05/2015
1	Essential Tremor (Essential Tremors) 05/2015
1	Hepatitis B 01/2014
1	Hepatitis C 01/2014
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 01/2014
1	Psychotic Disorders (Schizoaffective Disorder) 09/2013

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2002
5	Amyloid (Amyloid Fibrils)IBA 01/2023 - 01/2002
4	Amyloid beta-PeptidesIBA 11/2007 - 12/2003
3	Biomarkers (Surrogate Marker)IBA 01/2024 - 04/2008
3	Amino Acids FDA Link 12/2014 - 01/2014
3	Insulin (Novolin)FDA Link 05/2006 - 05/2004
3	Peptides (Polypeptides)IBA 04/2005 - 12/2003
2	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 05/2006
2	Complementary DNA (cDNA)IBA 12/2014 - 01/2014
2	AntibodiesIBA 01/2014 - 12/2012
2	Immunoglobulins (Immunoglobulin)IBA 01/2014 - 12/2012
2	Antipsychotic Agents (Antipsychotics)IBA 09/2013 - 05/2006
2	VaccinesIBA 01/2013 - 12/2012
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 09/2008 - 06/2008
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2008 - 06/2008
2	Insulysin (Insulin-Degrading Enzyme)IBA 06/2007 - 05/2004
2	Insulin ReceptorIBA 05/2006 - 05/2004
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 05/2004 - 12/2003
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 12/2003 - 01/2002
2	PolymersIBA 04/2003 - 01/2003
1	CholesterolIBA 05/2024
1	ProteomeIBA 01/2024
1	Factor XIII (Coagulation Factor XIII)IBA 01/2024
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2024
1	Histones (Histone)IBA 01/2024
1	ClusterinIBA 01/2024
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2023
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Dosage Forms (Dosage Form)IBA 12/2021
1	OpiumIBA 12/2021
1	Blood Glucose (Blood Sugar)IBA 12/2021
1	ChitosanIBA 11/2020
1	Coloring Agents (Dyes)IBA 11/2020
1	Biopolymers (Biopolymer)IBA 11/2020
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2020
1	Interleukin-12 (IL 12)IBA 07/2018
1	CytokinesIBA 07/2018
1	perifosineIBA 01/2018
1	ChromatinIBA 01/2018
1	Phosphotransferases (Kinase)IBA 09/2017
1	SandIBA 01/2017
1	Indoleacetic Acids (Auxin)IBA 01/2017
1	indolebutyric acidIBA 01/2017
1	HydrogenIBA 01/2016
1	Protons (Proton)IBA 01/2016
1	Dopamine D3 ReceptorsIBA 05/2015
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2015
1	Neutralizing AntibodiesIBA 01/2014
1	hepatitis B hyperimmune globulinIBA 01/2014
1	S-Adenosylmethionine (Ademetionine)IBA 01/2014
1	ethyleneIBA 01/2014
1	Methionine AdenosyltransferaseIBA 01/2014
1	EpitopesIBA 01/2014
1	PolyaminesIBA 01/2014
1	lumbrokinaseIBA 11/2013
1	Fibrinogen (Factor I)FDA Link 11/2013

Therapy/Procedure

4	Therapeutics 01/2022 - 04/2003
2	Drug Therapy (Chemotherapy) 01/2016 - 11/2007
1	Activities of Daily Living (ADL) 01/2024
1	Thrombectomy 01/2022
1	Immunotherapy 01/2016
1	Combination Drug Therapy (Combination Chemotherapy) 01/2016