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Peng Yang Selected Research

Endoplasmic Reticulum Chaperone BiP

3/2018Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways.
1/2018A Novel Doxorubicin Prodrug with GRP78 Recognition and Nucleus-Targeting Ability for Safe and Effective Cancer Therapy.
3/2017Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
1/2017GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
1/2017A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
1/2016Acetylation modification regulates GRP78 secretion in colon cancer cells.
7/2014GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the β-catenin signaling.
1/2014GRP78 secreted by colon cancer cells facilitates cell proliferation via PI3K/Akt signaling.

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Peng Yang Research Topics

Disease

150Neoplasms (Cancer)
04/2024 - 01/2004
45Infections
04/2024 - 08/2005
30Inflammation (Inflammations)
05/2024 - 03/2014
30Colorectal Neoplasms (Colorectal Cancer)
03/2024 - 11/2010
30Human Influenza (Influenza)
12/2020 - 09/2009
24Neoplasm Metastasis (Metastasis)
12/2023 - 10/2005
17Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2023 - 01/2005
16Wounds and Injuries (Trauma)
12/2023 - 01/2015
14Alzheimer Disease (Alzheimer's Disease)
11/2023 - 01/2017
13Myocardial Infarction
03/2024 - 08/2011
13Obesity
03/2023 - 11/2016
12Pain (Aches)
01/2024 - 12/2009
12Colonic Neoplasms (Colon Cancer)
03/2022 - 01/2014
11Lung Neoplasms (Lung Cancer)
01/2023 - 11/2005
10COVID-19
03/2024 - 01/2020
10Prostatic Neoplasms (Prostate Cancer)
01/2024 - 01/2020
10Breast Neoplasms (Breast Cancer)
03/2023 - 10/2011
9Ischemic Stroke
01/2024 - 01/2017
9Ischemia
06/2023 - 02/2017
8Disease Progression
05/2023 - 01/2019
8Reperfusion Injury
01/2023 - 02/2017
8Type 2 Diabetes Mellitus (MODY)
11/2022 - 01/2009
8Acute Lung Injury
12/2020 - 09/2004
7Stroke (Strokes)
03/2024 - 01/2016
7Fibrosis (Cirrhosis)
03/2024 - 01/2013
7Osteonecrosis (Kienbock's Disease)
01/2023 - 04/2019
7Stomach Neoplasms (Stomach Cancer)
02/2022 - 03/2012
7Carcinoma (Carcinomatosis)
01/2022 - 10/2015
6Aortic Dissection
04/2024 - 05/2019
6Virus Diseases (Viral Diseases)
04/2024 - 05/2011
6Myocardial Ischemia (Ischemic Heart Diseases)
01/2024 - 02/2017
6Dehydration (Water Stress)
12/2023 - 11/2017
6Hepatocellular Carcinoma (Hepatoma)
11/2023 - 02/2009
6Cerebral Hemorrhage
03/2023 - 01/2016
6Hematoma
03/2023 - 01/2015
6Cardiovascular Diseases (Cardiovascular Disease)
01/2023 - 05/2012
6Hypertension (High Blood Pressure)
01/2023 - 12/2011
6Sepsis (Septicemia)
10/2022 - 07/2005
6Lymphatic Metastasis
01/2022 - 01/2004
6Necrosis
01/2022 - 04/2018
6Carcinogenesis
01/2022 - 01/2014
6Influenza in Birds (Avian Flu)
01/2019 - 04/2010
5Brain Edema (Cerebral Edema)
03/2024 - 09/2015
5Neuroinflammatory Diseases
03/2024 - 09/2015
5Osteoarthritis
02/2024 - 11/2016
5Body Weight (Weight, Body)
11/2023 - 01/2017
5Thrombosis (Thrombus)
06/2023 - 09/2018
5Lung Injury
03/2023 - 05/2004
5Pancreatic Neoplasms (Pancreatic Cancer)
03/2023 - 01/2021
5Hemorrhage
03/2023 - 01/2016
5Adenocarcinoma
01/2023 - 07/2016

Drug/Important Bio-Agent (IBA)

64Proteins (Proteins, Gene)FDA Link
05/2024 - 08/2005
28Biomarkers (Surrogate Marker)IBA
03/2024 - 01/2014
25VaccinesIBA
01/2023 - 10/2010
21Long Noncoding RNAIBA
04/2024 - 10/2015
19Glucose (Dextrose)FDA LinkGeneric
02/2024 - 11/2010
18Messenger RNA (mRNA)IBA
01/2024 - 01/2009
15CytokinesIBA
05/2024 - 01/2015
14Therapeutic UsesIBA
02/2024 - 10/2015
13Peptides (Polypeptides)IBA
01/2024 - 01/2017
13EnzymesIBA
06/2023 - 01/2015
13MicroRNAs (MicroRNA)IBA
01/2023 - 09/2017
11SolutionsIBA
04/2023 - 11/2010
11Small Interfering RNA (siRNA)IBA
01/2023 - 10/2011
11Influenza Vaccines (Influenza Vaccine)FDA Link
01/2020 - 11/2012
10Blood Glucose (Blood Sugar)IBA
05/2023 - 01/2009
10CateninsIBA
01/2023 - 01/2014
9Reactive Oxygen Species (Oxygen Radicals)IBA
06/2023 - 01/2016
9Pyruvate KinaseIBA
10/2020 - 09/2014
8AlbuminsIBA
04/2024 - 10/2017
8RNA (Ribonucleic Acid)IBA
03/2024 - 01/2014
8Amyloid (Amyloid Fibrils)IBA
11/2023 - 01/2017
8Oxygen (Dioxygen)IBA
01/2021 - 05/2004
8Endoplasmic Reticulum Chaperone BiPIBA
03/2018 - 01/2014
7Interleukin-6 (Interleukin 6)IBA
01/2024 - 08/2011
7Antiviral Agents (Antivirals)IBA
12/2023 - 03/2012
7AntigensIBA
11/2023 - 10/2012
7ErbB Receptors (EGF Receptor)IBA
11/2023 - 04/2019
7DNA (Deoxyribonucleic Acid)IBA
07/2023 - 09/2006
7AntioxidantsIBA
06/2023 - 06/2018
7LigandsIBA
12/2022 - 02/2009
7Circular RNAIBA
01/2022 - 01/2021
7LipopolysaccharidesIBA
01/2021 - 09/2004
6AntibodiesIBA
11/2023 - 01/2012
6AcidsIBA
06/2023 - 07/2005
6C-Reactive ProteinIBA
05/2023 - 05/2012
6Antineoplastic Agents (Antineoplastics)IBA
03/2023 - 03/2014
5Protons (Proton)IBA
03/2024 - 08/2021
5ThioredoxinsIBA
12/2023 - 01/2016
5Protein Kinases (Protein Kinase)IBA
09/2023 - 04/2015
5Metal-Organic FrameworksIBA
08/2023 - 10/2017
5Indicators and Reagents (Reagents)IBA
04/2023 - 02/2012
5SteroidsIBA
01/2023 - 03/2009

Therapy/Procedure

73Therapeutics
04/2024 - 07/2005
14Drug Therapy (Chemotherapy)
08/2023 - 05/2008
9Immunotherapy
02/2024 - 10/2021
7Stents
04/2024 - 01/2020
7Gastrectomy
01/2023 - 10/2016
6Precision Medicine
04/2023 - 02/2016
5Intravenous Injections
09/2023 - 10/2017