Jianfeng Xing Selected Research

Drug Therapy (Chemotherapy)

12/2019	Transgelin 2 Promotes Paclitaxel Resistance, Migration, and Invasion of Breast Cancer by Directly Interacting with PTEN and Activating PI3K/Akt/GSK-3β Pathway.
7/2015	Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway.
1/2015	Salvianolic acid A reverses the paclitaxel resistance and inhibits the migration and invasion abilities of human breast cancer cells by inactivating transgelin 2.
10/2014	Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway.
6/2014	Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2.

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Jianfeng Xing Research Topics

Disease

13	Colitis 08/2023 - 04/2005
11	Breast Neoplasms (Breast Cancer) 12/2019 - 02/2014
10	Ulcerative Colitis 08/2023 - 04/2005
9	Neoplasms (Cancer) 02/2024 - 02/2014
7	Infections 01/2019 - 10/2011
5	Body Weight (Weight, Body) 01/2022 - 11/2014
4	Invasive Fungal Infections 01/2016 - 02/2014
3	Inflammation (Inflammations) 07/2023 - 03/2013
3	Neoplasm Metastasis (Metastasis) 01/2023 - 01/2017
3	Critical Illness (Critically Ill) 01/2017 - 10/2011
2	Hypoxia (Hypoxemia) 07/2023 - 01/2023
2	Bacterial Infections (Bacterial Infection) 01/2023 - 01/2017
2	Mycoses (Diseases, Fungus) 01/2021 - 10/2016
2	Carcinogenesis 12/2019 - 01/2017
2	Pulmonary Arterial Hypertension 08/2018 - 01/2018
2	Candidiasis (Moniliasis) 10/2016 - 02/2014
2	Aspergillosis 10/2016 - 02/2014
1	Rheumatoid Arthritis 09/2023
1	Wounds and Injuries (Trauma) 01/2023
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021
1	Lymphatic Metastasis 05/2019
1	Edema (Dropsy) 01/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Ventilator-Associated Pneumonia 01/2019

Drug/Important Bio-Agent (IBA)

9	Therapeutic UsesIBA 10/2020 - 03/2013
8	Paclitaxel (Taxol)FDA LinkGeneric 12/2019 - 02/2014
8	Proteins (Proteins, Gene)FDA Link 12/2019 - 02/2014
7	Voriconazole (Vfend)FDA LinkGeneric 01/2021 - 02/2014
5	AcidsIBA 07/2023 - 03/2013
4	Dexamethasone (Maxidex)FDA LinkGeneric 09/2023 - 01/2016
4	transgelinIBA 12/2019 - 06/2014
3	3,4-oxoisopropylideneshikimic acidIBA 02/2023 - 12/2012
3	Peroxidase (Myeloperoxidase)IBA 12/2019 - 03/2013
3	Glutathione (Reduced Glutathione)IBA 12/2019 - 01/2018
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 10/2011
3	Linezolid (Zyvox)FDA Link 01/2019 - 10/2011
3	Capsules (Microcapsules)IBA 03/2017 - 04/2005
2	Hyaluronic Acid (Hyaluronan)IBA 09/2023 - 08/2023
2	methylmethacrylate-methacrylic acid copolymerIBA 08/2023 - 03/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2023 - 01/2023
2	IonsIBA 01/2023 - 07/2022
2	Mesalamine (Mesalazine)FDA LinkGeneric 12/2019 - 01/2018
2	Glutathione PeroxidaseIBA 12/2019 - 01/2018
2	ProdrugsIBA 12/2019 - 01/2018
2	Malondialdehyde (Propanedial)IBA 12/2019 - 01/2018
2	Superoxide DismutaseIBA 12/2019 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 12/2019 - 05/2019
2	Small Interfering RNA (siRNA)IBA 11/2019 - 05/2019
2	Vancomycin FDA LinkGeneric 01/2019 - 01/2015
2	MonocrotalineIBA 08/2018 - 01/2018
2	baicaleinIBA 08/2018 - 01/2018
2	MicellesIBA 02/2018 - 01/2016
2	AntioxidantsIBA 02/2018 - 12/2012
2	tocophersolanIBA 02/2018 - 01/2016
2	HydrogelsIBA 01/2018 - 11/2014
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2018 - 03/2017
2	Methotrexate (Mexate)FDA LinkGeneric 01/2018 - 07/2014
2	SodiumIBA 01/2018 - 03/2017
2	Succinic Acid (Succinate)IBA 01/2018 - 03/2017
2	Tigecycline (Tygacil)FDA Link 01/2017 - 06/2014
2	Cytochrome P-450 CYP2C19IBA 01/2016 - 11/2014
2	salvianolic acid AIBA 01/2015 - 10/2014
2	Adenosine Triphosphate (ATP)IBA 10/2014 - 06/2014
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2014 - 06/2014
2	multidrug resistance-associated protein 1IBA 10/2014 - 06/2014
2	Acetic Acid (Vinegar)FDA LinkGeneric 12/2012 - 12/2002
1	CarbonIBA 09/2023
1	CyclodextrinsIBA 09/2023
1	ChitosanIBA 08/2023
1	Polysaccharides (Glycans)IBA 08/2023
1	SolutionsIBA 01/2023
1	Bovine Serum AlbuminIBA 01/2023
1	Silicon Dioxide (Silica)FDA LinkGeneric 01/2023
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2023
1	PolyphenolsIBA 01/2023
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023
1	LigandsIBA 01/2023
1	phytochlorinIBA 01/2023
1	MetalsIBA 01/2023
1	Oxygen (Dioxygen)IBA 01/2023
1	polydopamineIBA 01/2023
1	Caspofungin (Cancidas)FDA Link 01/2022
1	AlbuminsIBA 01/2022
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 10/2020
1	AnticoagulantsIBA 10/2020
1	MK 2206IBA 12/2019
1	Keratin-18 (Keratin 18)IBA 05/2019
1	Xylenes (Xylene)IBA 01/2019
1	LipopolysaccharidesIBA 01/2019
1	tedizolidIBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	CytokinesIBA 01/2019

Therapy/Procedure

8	Therapeutics 02/2024 - 07/2014
5	Drug Therapy (Chemotherapy) 12/2019 - 06/2014
2	Oral Administration 10/2020 - 12/2002
1	Intravenous Administration 07/2023
1	Hyperbaric Oxygenation 01/2023
1	Photochemotherapy (Photodynamic Therapy) 01/2023
1	Debridement 01/2023
1	Mechanical Ventilators (Ventilator) 01/2019