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N D Volkow Selected Research

Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)

6/2012Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain.
11/2011Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway.
6/2010Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors.
3/2006Therapeutic doses of amphetamine or methylphenidate differentially increase synaptic and extracellular dopamine.
11/2003Serum and brain concentrations of methylphenidate: implications for use and abuse.
3/2002Pharmacokinetic and pharmacodynamic properties of stimulants: implications for the design of new treatments for ADHD.
1/2002Mechanism of action of methylphenidate: insights from PET imaging studies.
1/2001Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain.
10/2000Comparison between intraperitoneal and oral methylphenidate administration: A microdialysis and locomotor activity study.

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N D Volkow Research Topics

Disease

9Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
06/2012 - 10/2000
4Substance-Related Disorders (Drug Abuse)
01/2012 - 03/2000
3Obesity
01/2012 - 02/2001
2Marijuana Abuse (Cannabis Abuse)
01/2017 - 06/2012
2Cocaine-Related Disorders (Cocaine Addiction)
03/2016 - 03/2012
2Alcoholism (Alcohol Abuse)
09/2015 - 09/2001
2Cognitive Dysfunction
09/2007 - 03/2001
1Sleep Deprivation
01/2016
1Weight Loss (Weight Reduction)
05/2014
1Mental Fatigue
10/2012
1Stroke (Strokes)
10/2012
1Language Disorders (Language Disorder)
07/2012
1Genetic Predisposition to Disease (Genetic Predisposition)
07/2008
1Parkinsonian Disorders (Parkinsonism)
12/2001
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2001
1Psychomotor Disorders
03/2001
1Amyloid Plaque
02/2001
1Dementia (Dementias)
02/2001
1Alzheimer Disease (Alzheimer's Disease)
02/2001
1Bradycardia
09/2000
1Sleepiness
06/2000
1Dehydration (Water Stress)
06/2000
1Dizziness (Lightheadedness)
06/2000

Drug/Important Bio-Agent (IBA)

15Dopamine (Intropin)FDA LinkGeneric
01/2017 - 10/2000
7Methylphenidate (Ritalin)FDA LinkGeneric
06/2010 - 10/2000
5Cocaine (Cocaine HCl)IBA
03/2016 - 09/2007
3Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
09/2015 - 03/2001
3Glucose (Dextrose)FDA LinkGeneric
07/2008 - 09/2000
2Amphetamine (Amfetamine)FDA LinkGeneric
06/2010 - 03/2006
2Methamphetamine (Desoxyn)FDA LinkGeneric
12/2001 - 03/2001
2Ethanol (Ethyl Alcohol)IBA
06/2000 - 06/2000
1NicotineFDA Link
01/2017
1Opioid Receptors (Opioid Receptor)IBA
05/2014
1Naltrexone (ReVia)FDA LinkGeneric
05/2014
1Pro-Opiomelanocortin (Proopiomelanocortin)IBA
05/2014
1Bupropion (Wellbutrin)FDA LinkGeneric
05/2014
1Biomarkers (Surrogate Marker)IBA
07/2012
1Dopamine D4 Receptors (Dopamine D4 Receptor)IBA
06/2012
1dopamine D2L receptorIBA
06/2012
1CannabinoidsIBA
06/2012
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
03/2012
1Genetic Markers (Genetic Marker)IBA
03/2012
1RacloprideIBA
11/2011
1Adenosine Monophosphate (AMP)IBA
03/2006
1Acetylcholine (Acetylcholine Chloride)FDA Link
02/2001
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
02/2001
1Cholinergic Agents (Cholinergics)IBA
02/2001
1AcetylcholinesteraseIBA
02/2001
1Psychotropic Drugs (Psychoactive Drugs)IBA
01/2001
1Therapeutic UsesIBA
01/2001
1Lorazepam (Ativan)FDA LinkGeneric
06/2000
1Protons (Proton)IBA
06/2000
1Hypnotics and Sedatives (Sedatives)IBA
06/2000

Therapy/Procedure

1Therapeutics
05/2014
1Self Administration (Administration, Self)
03/2000