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Eduardo Tolosa Selected Research

rasagiline (Azilect)

6/2014Symptomatic efficacy of rasagiline monotherapy in early Parkinson's disease: post-hoc analyses from the ADAGIO trial.
5/2011A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes.
9/2009A double-blind, delayed-start trial of rasagiline in Parkinson's disease.
4/2009Validation of the freezing of gait questionnaire in patients with Parkinson's disease.
11/2008A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics.

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Eduardo Tolosa Research Topics

Disease

98Parkinson Disease (Parkinson's Disease)
01/2022 - 03/2002
20Dementia (Dementias)
01/2021 - 09/2002
20Parkinsonian Disorders (Parkinsonism)
01/2021 - 04/2002
12Dyskinesias (Dyskinesia)
10/2018 - 01/2002
9Alzheimer Disease (Alzheimer's Disease)
09/2012 - 12/2003
7Neurodegenerative Diseases (Neurodegenerative Disease)
12/2021 - 09/2003
7REM Sleep Behavior Disorder
05/2021 - 02/2015
7Synucleinopathies
05/2021 - 09/2003
6Multiple System Atrophy
01/2021 - 06/2007
6Tremor (Tremors)
01/2015 - 07/2007
5Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
04/2014 - 08/2002
4Cognitive Dysfunction
01/2018 - 02/2008
4Hypokinesia (Bradykinesia)
01/2015 - 10/2007
3Deglutition Disorders (Dysphagia)
03/2022 - 01/2018
3Movement Disorders (Movement Disorder)
08/2014 - 06/2012
3Atrophy
04/2014 - 12/2011
3Tauopathies
08/2005 - 12/2003
2Inflammation (Inflammations)
05/2021 - 10/2020
2Neuroinflammatory Diseases
12/2020 - 10/2017
2Respiratory Sounds (Crackle)
10/2019 - 10/2003
2Dystonia (Limb Dystonia)
06/2014 - 12/2006
2Diarrhea
04/2014 - 11/2013
2Fatigue
11/2013 - 05/2011
2Dizziness (Lightheadedness)
11/2013 - 01/2011
2Disease Progression
06/2010 - 09/2009
2Disorders of Excessive Somnolence (Hypersomnia)
12/2009 - 09/2007
2Essential Tremor (Essential Tremors)
10/2007 - 07/2007
1Malnutrition (Nutritional Deficiencies)
01/2021
1Neoplasms (Cancer)
01/2019
1Fibrosis (Cirrhosis)
01/2018
1Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
06/2015
1Paraneoplastic Cerebellar Degeneration
06/2015
1Prodromal Symptoms
05/2015
1Dysarthria (Spastic Dysarthria)
06/2014

Drug/Important Bio-Agent (IBA)

31Levodopa (L Dopa)FDA LinkGeneric
01/2021 - 01/2002
16SynucleinsIBA
05/2021 - 09/2003
16Phosphotransferases (Kinase)IBA
01/2021 - 04/2003
13Leucine (L-Leucine)FDA Link
01/2021 - 06/2007
11Biomarkers (Surrogate Marker)IBA
05/2021 - 01/2011
7Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
01/2021 - 10/2004
7Dopamine (Intropin)FDA LinkGeneric
01/2018 - 09/2005
6Pharmaceutical PreparationsIBA
10/2019 - 01/2002
5alpha-SynucleinIBA
07/2014 - 09/2003
5rasagiline (Azilect)FDA Link
06/2014 - 11/2008
4Carbidopa (Lodosyn)FDA LinkGeneric
11/2017 - 07/2010
4Messenger RNA (mRNA)IBA
06/2015 - 12/2002
4ioflupaneIBA
08/2014 - 10/2004
4entacapone (Comtan)FDA Link
04/2014 - 04/2009
3Proteins (Proteins, Gene)FDA Link
05/2021 - 09/2003
3opicaponeIBA
01/2021 - 07/2017
3Cholinergic Agents (Cholinergics)IBA
12/2020 - 09/2007
3Dopamine Agonists (Dopamine Agonist)IBA
01/2018 - 10/2009
3rotigotineFDA Link
01/2018 - 06/2007
3perampanelIBA
02/2012 - 05/2010
3UbiquitinIBA
06/2010 - 12/2003
3Pramipexole (Mirapex)FDA LinkGeneric
06/2010 - 11/2006
2mesoglycanIBA
03/2022 - 11/2021
2Glucosylceramidase (Glucocerebrosidase)IBA
11/2019 - 01/2018
2DNA (Deoxyribonucleic Acid)IBA
10/2019 - 07/2014
2Amyloid (Amyloid Fibrils)IBA
08/2016 - 01/2011
2Glycogen Synthase Kinase 3IBA
04/2014 - 12/2003
2tau Proteins (tau Protein)IBA
04/2014 - 05/2004
2Excitatory Amino Acid AntagonistsIBA
01/2012 - 02/2004
22- carbomethoxy- 8- (3- fluoropropyl)- 3- (4- iodophenyl)tropaneIBA
12/2011 - 03/2009
23-Iodobenzylguanidine (Iobenguane)IBA
06/2011 - 06/2011
2OrexinsIBA
12/2009 - 09/2007
2ApomorphineFDA Link
06/2009 - 12/2004
2Protein Isoforms (Isoforms)IBA
08/2005 - 08/2002
1HLA-DRB1 Chains (HLA DRB1)IBA
01/2022
1CoffeeFDA Link
01/2022
1Glucose (Dextrose)FDA LinkGeneric
12/2021
1Biological ProductsIBA
05/2021
13-nitrotyrosineIBA
05/2021
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2021
1AcetylcholinesteraseIBA
12/2020
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2020
1Mitochondrial DNA (mtDNA)IBA
10/2019
1TransferasesIBA
10/2018
1catechol (pyrocatechol)IBA
10/2018
1Dynamin IIIIBA
01/2018
1ErgolinesIBA
01/2018
1Cystatin CIBA
06/2015
1CathepsinsIBA
06/2015
1MicroRNAs (MicroRNA)IBA
05/2015
1neuromelaninIBA
01/2015
1ManganeseIBA
06/2014
1monomethylpropion (methcathinone)IBA
06/2014
1Transaminases (Aminotransferases)IBA
04/2014
1Alanine Transaminase (SGPT)IBA
04/2014
1Glycogen Synthase (Synthase I)IBA
04/2014
1tideglusibIBA
04/2014

Therapy/Procedure

16Therapeutics
01/2021 - 12/2004
6Deep Brain Stimulation
01/2019 - 03/2002
2Activities of Daily Living (ADL)
01/2018 - 02/2006
2Denervation
03/2016 - 12/2011
1Gastrostomy
01/2021
1Tracheostomy
10/2019
1Continuous Positive Airway Pressure
10/2019
1Transdermal Patch
01/2018
1Drug Therapy (Chemotherapy)
01/2018