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Kazuhiro Takahashi Selected Research

Prorenin Receptor

12/2022(Pro)renin receptor and insulin signalling regulate cell proliferation in MCF-7 breast cancer cells.
10/2021Elevated (Pro)renin Receptor Expression by Anti-Cancer Drugs, Carboplatin and Paclitaxel, in Cultured Cancer Cells: Possible Involvement of Apoptosis and Autophagy.
12/2020(Pro)renin receptor/ATP6AP2 is required for autophagy and regulates proliferation in lung adenocarcinoma cells.
7/2020Increased soluble (pro)renin receptor protein by autophagy inhibition in cultured cancer cells.
1/2018Decrease of Plasma Soluble (Pro)renin Receptor by Bariatric Surgery in Patients with Obstructive Sleep Apnea and Morbid Obesity.
6/2017Soluble (Pro)renin Receptor and Obstructive Sleep Apnea Syndrome: Oxidative Stress in Brain?
1/2017Expression of (Pro)renin Receptor During Rapamycin-Induced Erythropoiesis in K562 Erythroleukemia Cells and Its Possible Dual Actions on Erythropoiesis.
1/2016Water Deprivation Increases (Pro)renin Receptor Levels in the Kidney and Decreases Plasma Concentrations of Soluble (Pro)renin Receptor.
1/2016Elevated Plasma Levels of Soluble (Pro)Renin Receptor in Patients with Obstructive Sleep Apnea Syndrome in Parallel with the Disease Severity.
10/2015Ubiquitous expression and multiple functions of biologically active peptides.
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Kazuhiro Takahashi Research Topics

Disease

61Neoplasms (Cancer)
04/2024 - 06/2002
26Chronic Hepatitis C
02/2022 - 02/2006
20Infections
02/2022 - 05/2007
13Fibrosis (Cirrhosis)
02/2023 - 01/2006
12Carcinoma (Carcinomatosis)
03/2024 - 08/2002
12Ovarian Neoplasms (Ovarian Cancer)
09/2017 - 09/2002
12Hypoxia (Hypoxemia)
10/2015 - 08/2002
11Neoplasm Metastasis (Metastasis)
11/2022 - 08/2004
11Hepatocellular Carcinoma (Hepatoma)
01/2022 - 03/2013
11Hypertension (High Blood Pressure)
01/2020 - 02/2004
11Melanoma (Melanoma, Malignant)
02/2018 - 07/2004
9Heart Failure
09/2023 - 02/2004
9Breast Neoplasms (Breast Cancer)
12/2022 - 10/2003
9Pheochromocytoma
09/2021 - 06/2002
8Obstructive Sleep Apnea
01/2018 - 03/2003
8Adenoma (Adenomas)
03/2014 - 02/2003
7Inflammation (Inflammations)
09/2023 - 10/2002
6Prostatic Neoplasms (Prostate Cancer)
11/2022 - 01/2020
6Chronic Hepatitis B
04/2022 - 01/2005
6Ascites
01/2021 - 05/2004
6Renal Cell Carcinoma (Grawitz Tumor)
01/2021 - 08/2002
6Chronic Kidney Failure (Chronic Renal Failure)
11/2020 - 02/2009
6Liver Diseases (Liver Disease)
10/2018 - 01/2006
5Ischemia
05/2024 - 01/2002
5Adenocarcinoma
01/2024 - 07/2011
5Insulin Resistance
01/2021 - 02/2003
5Pain (Aches)
02/2019 - 11/2005
5Tachycardia (Tachyarrhythmias)
11/2018 - 06/2009
5Diabetes Mellitus
06/2018 - 01/2003
5Cardiovascular Diseases (Cardiovascular Disease)
04/2015 - 02/2004
5Renal Insufficiency (Renal Failure)
07/2010 - 04/2004
4Abdominal Pain (Pain, Abdominal)
05/2024 - 01/2008
4Virus Diseases (Viral Diseases)
07/2021 - 07/2012
4Chronic Renal Insufficiency
01/2020 - 08/2009
4Thrombocytopenia (Thrombopenia)
10/2019 - 12/2013
4Liver Cirrhosis (Hepatic Cirrhosis)
06/2018 - 05/2007
4Anemia
12/2016 - 10/2013
4Neuroblastoma
11/2011 - 06/2002
4Adrenocortical Carcinoma
05/2010 - 08/2002
3Proteinuria
04/2024 - 08/2009
3Esophageal Neoplasms (Esophageal Cancer)
01/2024 - 12/2021
3Wounds and Injuries (Trauma)
01/2024 - 02/2017
3Glomerulonephritis
08/2022 - 11/2020
3Polyuria
07/2022 - 06/2017
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
07/2022 - 01/2018
3Body Weight (Weight, Body)
04/2022 - 01/2021

Drug/Important Bio-Agent (IBA)

19InterferonsIBA
02/2022 - 05/2007
19Ribavirin (Virazole)FDA LinkGeneric
06/2019 - 02/2006
17Prorenin ReceptorIBA
12/2022 - 08/2009
15Messenger RNA (mRNA)IBA
12/2023 - 06/2002
15Peptides (Polypeptides)IBA
11/2022 - 06/2002
13Proteins (Proteins, Gene)FDA Link
04/2024 - 07/2004
11AdrenomedullinIBA
10/2015 - 10/2002
9Oxygen (Dioxygen)IBA
02/2023 - 03/2003
9CytokinesIBA
10/2015 - 08/2002
8Antiviral Agents (Antivirals)IBA
02/2022 - 10/2013
8SofosbuvirIBA
09/2020 - 12/2016
8Cisplatin (Platino)FDA LinkGeneric
01/2018 - 03/2004
8telaprevirIBA
12/2015 - 08/2013
8UrocortinsIBA
04/2014 - 01/2002
8urotensin IIIBA
08/2009 - 01/2003
6Paclitaxel (Taxol)FDA LinkGeneric
10/2021 - 09/2002
6Estrogens (Estrogen)FDA Link
11/2018 - 10/2002
6Endothelin-1 (Endothelin 1)IBA
10/2015 - 08/2002
6AldosteroneIBA
03/2014 - 01/2006
6OrexinsIBA
11/2005 - 03/2003
5GlucocorticoidsIBA
12/2020 - 04/2003
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2013 - 09/2003
5Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
04/2006 - 09/2002
4GemcitabineFDA Link
07/2023 - 10/2013
4Insulin (Novolin)FDA Link
12/2022 - 12/2008
4Glucose (Dextrose)FDA LinkGeneric
12/2022 - 12/2008
4entecavirFDA Link
04/2022 - 01/2020
4Tenofovir (Viread)FDA Link
04/2022 - 01/2020
4DNA (Deoxyribonucleic Acid)IBA
12/2021 - 01/2006
4Small Interfering RNA (siRNA)IBA
10/2021 - 07/2012
4Hemoglobins (Hemoglobin)IBA
12/2016 - 01/2008
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2014 - 11/2003
4Vasodilator Agents (Vasodilators)IBA
01/2012 - 09/2003
4Hydrocortisone (Cortisol)FDA LinkGeneric
05/2010 - 01/2006
3SteroidsIBA
04/2024 - 09/2009
31,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA
04/2024 - 01/2015
3AlbuminsIBA
04/2024 - 06/2018
3Therapeutic UsesIBA
04/2024 - 12/2003
3NivolumabIBA
10/2023 - 01/2018
3Protons (Proton)IBA
07/2023 - 06/2021
3LigandsIBA
07/2023 - 01/2002
3HLA Antigens (Human Leukocyte Antigens)IBA
01/2023 - 01/2018
3AndrogensIBA
11/2022 - 11/2018

Therapy/Procedure

39Therapeutics
05/2024 - 11/2003
12Drug Therapy (Chemotherapy)
12/2023 - 08/2013
8Hepatectomy
01/2022 - 03/2013
7Liver Transplantation
01/2024 - 04/2016
4Esophagectomy
01/2024 - 12/2021
4Ligation
12/2022 - 05/2008
4Renal Dialysis (Hemodialysis)
06/2019 - 04/2004
4Catheter Ablation
03/2016 - 08/2008
3Neoadjuvant Therapy
12/2023 - 10/2021
3Adjuvant Chemotherapy
12/2023 - 12/2013
3Gastrectomy
07/2022 - 08/2013