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Gregory Stephanopoulos Selected Research

Insulin (Novolin)

8/2012Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway.
7/2010The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
7/2007Linking hepatic transcriptional changes to high-fat diet induced physiology for diabetes-prone and obese-resistant mice.
4/2007The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance.
6/2005Regulation of mouse hepatic genes in response to diet induced obesity, insulin resistance and fasting induced weight reduction.
10/2004Short-term resistance to diet-induced obesity in A/J mice is not associated with regulation of hypothalamic neuropeptides.

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Gregory Stephanopoulos Research Topics

Disease

23Neoplasms (Cancer)
04/2024 - 07/2010
6Insulin Resistance
01/2022 - 06/2005
4Obesity
01/2022 - 10/2004
4Hepatocellular Carcinoma (Hepatoma)
05/2011 - 10/2004
3Hypoxia (Hypoxemia)
05/2017 - 11/2011
3Carcinogenesis
10/2012 - 07/2010
2Starvation
12/2019 - 01/2016
2Pancreatic Neoplasms (Pancreatic Cancer)
02/2017 - 08/2015
1Lung Neoplasms (Lung Cancer)
10/2023
1Inflammation (Inflammations)
01/2022
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022
1Hypersensitivity (Allergy)
12/2019
1Renal Cell Carcinoma (Grawitz Tumor)
05/2017
1Kidney Neoplasms (Kidney Cancer)
05/2017
1Prostatic Neoplasms (Prostate Cancer)
07/2013
1Melanoma (Melanoma, Malignant)
05/2013
1Hyperinsulinism (Hyperinsulinemia)
08/2012
1Colonic Neoplasms (Colon Cancer)
08/2012
1Carcinoma (Carcinomatosis)
08/2011
1Confusion (Bewilderment)
08/2010
1Neoplasm Metastasis (Metastasis)
07/2010
1Bacterial Infections (Bacterial Infection)
10/2006
1Metabolic Diseases (Metabolic Disease)
07/2006
1Weight Loss (Weight Reduction)
06/2005
1Body Weight (Weight, Body)
10/2004
1Mouth Neoplasms (Oral Cancer)
04/2003

Drug/Important Bio-Agent (IBA)

11Glutamine (L-Glutamine)FDA Link
05/2017 - 11/2009
10Glucose (Dextrose)FDA LinkGeneric
01/2022 - 10/2004
6CarbonIBA
05/2017 - 07/2011
6Insulin (Novolin)FDA Link
08/2012 - 10/2004
4Proteins (Proteins, Gene)FDA Link
02/2017 - 10/2006
3IsotopesIBA
10/2023 - 07/2006
3Amino AcidsFDA Link
12/2019 - 01/2014
3NitrogenIBA
12/2019 - 01/2016
2NADP (NADPH)IBA
04/2024 - 01/2016
2LipidsIBA
05/2017 - 08/2010
2Protein Isoforms (Isoforms)IBA
01/2015 - 10/2012
2Pyruvate KinaseIBA
01/2015 - 10/2012
2Fatty Acids (Saturated Fatty Acids)IBA
01/2013 - 11/2011
2Serine (L-Serine)FDA Link
08/2012 - 07/2011
2Lactic Acid (Lactate)FDA LinkGeneric
11/2011 - 07/2011
2Messenger RNA (mRNA)IBA
08/2011 - 07/2010
2Phosphatidylinositols (Phosphatidylinositol)IBA
07/2010 - 04/2007
1Biomarkers (Surrogate Marker)IBA
10/2023
1CytokinesIBA
01/2022
1Lipid PeroxidesIBA
10/2020
1AldehydesIBA
10/2020
1CaspasesIBA
10/2020
1NucleotidesIBA
10/2020
1Membrane LipidsIBA
12/2019
1Ethanol (Ethyl Alcohol)IBA
12/2019
1isobutyl alcohol (isobutanol)IBA
12/2019
1Citric Acid (Citrate)FDA LinkGeneric
05/2017
1GlutaminaseIBA
05/2017
1pyrimidineIBA
05/2017
1Poly(ADP-ribose) Polymerase InhibitorsIBA
05/2017
1AlbuminsIBA
02/2017
1Adenosine Triphosphate (ATP)IBA
01/2016
1NAD (NADH)IBA
01/2016
1Acetyl Coenzyme A (Acetyl-CoA)IBA
01/2016
1Polytetrafluoroethylene (Teflon)FDA Link
08/2015
1Carbon-13IBA
01/2014
1Metformin (Glucophage)FDA LinkGeneric
07/2013
1Mechanistic Target of Rapamycin Complex 1IBA
05/2013
1isocitric acid (isocitrate)IBA
11/2011
1Glycine (Aminoacetic Acid)FDA LinkGeneric
07/2011
1Phosphoglycerate Dehydrogenase (Dehydrogenase, Phosphoglycerate)IBA
07/2011
1ElementsIBA
08/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2010
1Oleic Acid (Oleate)IBA
11/2009
1PalmitatesIBA
11/2009
1Insulin ReceptorIBA
02/2008
1Phosphotransferases (Kinase)IBA
04/2007
1JNK Mitogen-Activated Protein KinasesIBA
04/2007
1Antimicrobial PeptidesIBA
10/2006
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
06/2005
1RNA (Ribonucleic Acid)IBA
10/2004
1Green Fluorescent ProteinsIBA
10/2004
1CorticosteroneIBA
10/2004
1NeuropeptidesIBA
10/2004
1Peptides (Polypeptides)IBA
10/2004
1Nonesterified Fatty Acids (NEFA)IBA
10/2004
1Mitochondrial Uncoupling ProteinsIBA
10/2004
1DNA (Deoxyribonucleic Acid)IBA
04/2003

Therapy/Procedure

2Therapeutics
01/2017 - 11/2012
1Drug Therapy (Chemotherapy)
01/2022
1Plasma Exchange
02/2017
1Aftercare (After-Treatment)
05/2011
1Caloric Restriction
06/2005
1Fat-Restricted Diet (Diet, Fat Restricted)
10/2004