Philip C Spinella Selected Research

Hemorrhage

4/2024	Massive Transfusion in Pediatric Patients on Extracorporeal Membrane Oxygenation: A Secondary Analysis of the Massive Transfusion in Children (MATIC) Study.
4/2024	Receipt of RhD-positive whole blood for life-threatening bleeding in female children: A survey in alloimmunized mothers regarding minimum acceptable survival benefit relative to risk of maternal alloimmunization to anti-D.
3/2024	Increased platelet to red blood cell transfusion ratio associated with acute kidney injury in children with life-threatening bleeding.
3/2024	The Efficacy of Low-Titer Group O Whole Blood Compared With Component Therapy in Civilian Trauma Patients: A Meta-Analysis.
3/2024	Analyzing and modeling massive transfusion strategies and the role of fibrinogen-How much is the patient actually receiving?
12/2023	Cold-stored platelet hemostatic capacity is maintained for three weeks of storage and associated with taurine metabolism.
12/2023	Not as "D"eadly as once thought - the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma.
10/2023	Damage-control resuscitation in pediatric trauma: What you need to know.
1/2023	Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children.
1/2023	Design and logistical considerations for the randomized adaptive non-inferiority storage-duration-ranging CHIlled Platelet Study.

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Philip C Spinella Research Topics

Disease

56	Hemorrhage 04/2024 - 02/2008
54	Wounds and Injuries (Trauma) 05/2024 - 01/2007
24	Hemorrhagic Shock 05/2024 - 04/2009
23	Critical Illness (Critically Ill) 03/2023 - 07/2004
14	Shock 10/2023 - 08/2010
6	Anemia 01/2023 - 08/2017
4	Multiple Organ Failure (MODS) 09/2023 - 09/2010
4	COVID-19 03/2023 - 01/2021
4	Sepsis (Septicemia) 01/2023 - 01/2018
4	Thrombosis (Thrombus) 11/2022 - 01/2021
3	Hypothermia 10/2023 - 11/2009
3	Heart Arrest (Cardiac Arrest) 01/2023 - 01/2013
3	Venous Thrombosis (Deep-Vein Thrombosis) 01/2021 - 02/2013
3	Transfusion-Related Acute Lung Injury 12/2020 - 01/2018
3	Traumatic Brain Injuries (Traumatic Brain Injury) 09/2017 - 03/2003
3	Hypotension (Low Blood Pressure) 01/2016 - 11/2008
2	Thrombocytopenia (Thrombopenia) 05/2024 - 01/2019
2	Lung Injury 05/2024 - 07/2020
2	Acute Kidney Injury (Acute Renal Failure) 03/2024 - 01/2023
2	Acidosis 10/2023 - 11/2009
2	Heart Diseases (Heart Disease) 01/2023 - 01/2023
2	Body Weight (Weight, Body) 01/2022 - 01/2018
2	Drug-Related Side Effects and Adverse Reactions 01/2022 - 01/2020
2	Infections 06/2021 - 01/2019
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020 - 01/2020
2	Transfusion Reaction 01/2019 - 05/2014
1	Multiple Trauma (Multiple Injuries) 12/2023
1	Perinatal Death 12/2023
1	Iron Overload 10/2023
1	Coinfection 03/2023
1	Hemolysis 01/2023
1	Human Influenza (Influenza) 01/2023
1	Venous Thromboembolism 01/2023
1	Arterial Occlusive Diseases (Arterial Occlusive Disease) 11/2022
1	Nervous System Diseases (Neurological Disorders) 11/2022
1	Disease Progression 05/2022
1	Stroke (Strokes) 01/2022
1	Delirium 01/2022
1	Thromboembolism 01/2022
1	Lymphopenia (Lymphocytopenia) 06/2021

Drug/Important Bio-Agent (IBA)

27	Hemostatics (Antihemorrhagics)IBA 03/2024 - 03/2009
8	Tranexamic Acid (AMCA)FDA Link 05/2024 - 01/2017
8	Hemoglobins (Hemoglobin)IBA 01/2023 - 04/2009
6	Oxygen (Dioxygen)IBA 01/2020 - 01/2013
5	Fibrinogen (Factor I)FDA Link 01/2021 - 02/2008
4	Crystalloid SolutionsIBA 01/2018 - 01/2010
3	Interleukin-6 (Interleukin 6)IBA 12/2023 - 04/2015
3	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2023 - 01/2022
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2017
3	Thrombin FDA Link 01/2022 - 01/2021
3	Colloids (Colloid)IBA 04/2016 - 01/2010
3	recombinant FVIIa (rFVIIa)FDA Link 08/2010 - 02/2008
3	S100 Calcium Binding Protein beta SubunitIBA 05/2004 - 03/2003
2	Aminocaproic Acid (6 Aminocaproic Acid)FDA LinkGeneric 01/2023 - 01/2022
2	TESIBA 01/2022 - 01/2020
2	Enoxaparin (Lovenox)FDA LinkGeneric 01/2021 - 01/2021
2	Detergents (Detergent)IBA 01/2020 - 05/2017
2	SolventsIBA 01/2020 - 05/2017
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2020 - 11/2009
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2019 - 01/2016
2	AnticoagulantsIBA 01/2018 - 04/2009
2	Factor VIIa (Activated Factor VII)IBA 03/2009 - 02/2008
2	Blood Proteins (Serum Proteins)IBA 05/2004 - 03/2003
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 05/2024
1	Antineoplastic Agents (Antineoplastics)IBA 05/2024
1	CalciumIBA 04/2024
1	RHO(D) antibody (anti-D)IBA 04/2024
1	Cystatin CIBA 12/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2023
1	BilirubinIBA 01/2023
1	CreatinineIBA 01/2023
1	HaptoglobinsIBA 01/2023
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2023
1	PotassiumIBA 01/2023
1	von Willebrand FactorIBA 11/2022
1	Citric Acid (Citrate)FDA LinkGeneric 01/2022
1	Famciclovir (Famvir)FDA LinkGeneric 06/2021
1	Acyclovir (Aciclovir)FDA LinkGeneric 06/2021
1	Antiviral Agents (Antivirals)IBA 06/2021
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2021

Therapy/Procedure

54	Resuscitation 05/2024 - 03/2009
24	Therapeutics 05/2024 - 07/2008
13	Platelet Transfusion (Blood Platelet Transfusions) 05/2024 - 02/2011
11	Erythrocyte Transfusion 03/2024 - 02/2008
10	Critical Care (Surgical Intensive Care) 03/2023 - 09/2009
8	Artificial Respiration (Mechanical Ventilation) 05/2024 - 07/2004
8	Extracorporeal Membrane Oxygenation 04/2024 - 08/2008
7	Blood Transfusion (Blood Transfusions) 03/2024 - 07/2008
5	Blood Component Removal (Apheresis) 01/2020 - 04/2009
3	Perioperative Period 01/2022 - 09/2010
3	Central Venous Catheters 01/2021 - 02/2013
2	Liver Transplantation 03/2024 - 01/2020
2	Hemodilution 10/2023 - 11/2009
2	Cardiopulmonary Bypass (Heart-Lung Bypass) 09/2023 - 01/2019
2	Mechanical Ventilators (Ventilator) 01/2023 - 01/2020
2	Length of Stay 01/2023 - 01/2023
2	Catheters 01/2021 - 01/2021
1	Operative Surgical Procedures 01/2023
1	Heart-Assist Devices 01/2022
1	Hematopoietic Stem Cell Transplantation 06/2021