Diogo Onofre Souza Selected Research

Malaria

1/2022	Dynamics and immunomodulation of cognitive deficits and behavioral changes in non-severe experimental malaria.
1/2021	IMXQB-80: A Quillaja brasiliensis saponin-based nanoadjuvant enhances Zika virus specific immune responses in mice.

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Diogo Onofre Souza Research Topics

Disease

9	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 06/2014
9	Seizures (Absence Seizure) 01/2019 - 07/2003
6	Brain Ischemia (Cerebral Ischemia) 03/2016 - 06/2002
5	Inflammation (Inflammations) 11/2022 - 04/2017
5	Insulin Resistance 04/2017 - 04/2010
4	Brain Injuries (Brain Injury) 08/2022 - 08/2006
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 10/2013
4	Cognitive Dysfunction 05/2019 - 01/2009
4	Hyperammonemia 05/2018 - 01/2012
4	Ischemia 03/2016 - 12/2012
3	Alzheimer Disease (Alzheimer's Disease) 04/2021 - 12/2012
3	Gliosis 10/2019 - 05/2008
3	Hepatic Encephalopathy 05/2018 - 12/2015
3	Neoplasms (Cancer) 01/2017 - 07/2003
3	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 01/2017 - 03/2011
3	Epilepsy (Aura) 06/2014 - 07/2003
2	Infections 01/2022 - 12/2020
2	Malaria 01/2022 - 01/2021
2	Neuroinflammatory Diseases 01/2020 - 10/2018
2	Glutaric Acidemia I 10/2019 - 01/2018
2	Neuromyelitis Optica (Devic's Disease) 01/2019 - 01/2010
2	Body Weight (Weight, Body) 04/2017 - 06/2013
2	Parkinson Disease (Parkinson's Disease) 02/2011 - 02/2004
2	Status Epilepticus (Complex Partial Status Epilepticus) 01/2011 - 05/2008
2	Vascular Diseases (Vascular Disease) 10/2010 - 04/2010
2	Malnutrition (Nutritional Deficiencies) 10/2006 - 04/2005
1	Zika Virus Infection 01/2023
1	Methylmalonic acidemia 11/2022
1	Diphtheria 01/2022
1	Tetanus 01/2022
1	Schizophrenia (Dementia Praecox) 01/2021
1	Mental Disorders (Mental Disorder) 01/2021
1	Herpes Zoster 01/2021
1	Demyelinating Diseases (Demyelinating Disease) 10/2019
1	Chronic Disease (Chronic Diseases) 10/2019

Drug/Important Bio-Agent (IBA)

12	Glutamic Acid (Glutamate)FDA Link 01/2023 - 06/2002
9	GuanosineIBA 03/2016 - 06/2002
8	Proteins (Proteins, Gene)FDA Link 01/2018 - 04/2005
6	CytokinesIBA 12/2020 - 10/2015
5	ResveratrolIBA 11/2022 - 06/2014
5	AmmoniaIBA 05/2018 - 01/2012
5	AntioxidantsIBA 04/2017 - 01/2012
4	Neuroprotective AgentsIBA 01/2020 - 02/2004
4	Glucose (Dextrose)FDA LinkGeneric 10/2019 - 01/2013
4	Quinolinic AcidIBA 12/2011 - 07/2003
3	Glutathione (Reduced Glutathione)IBA 11/2022 - 07/2014
3	Glutaryl-CoA DehydrogenaseIBA 10/2019 - 01/2017
3	Biomarkers (Surrogate Marker)IBA 08/2018 - 08/2006
3	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2018 - 07/2014
3	LipidsIBA 04/2017 - 04/2010
3	Heme Oxygenase-1IBA 04/2017 - 06/2014
3	CatalaseIBA 04/2016 - 09/2007
3	Insulin (Novolin)FDA Link 04/2016 - 10/2010
3	Superoxide DismutaseIBA 04/2016 - 09/2007
2	EnzymesIBA 05/2019 - 01/2017
2	Immunoglobulin G (IgG)IBA 01/2019 - 01/2010
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2019 - 01/2013
2	Risperidone (Risperdal Consta)FDA LinkGeneric 10/2018 - 02/2009
2	Trans Fatty AcidsIBA 08/2018 - 04/2017
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2017 - 07/2014
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2017 - 07/2014
2	Superoxides (Superoxide)IBA 01/2017 - 07/2014
2	NeurotoxinsIBA 02/2016 - 01/2012
2	NitrogenIBA 12/2015 - 07/2014
2	Oxygen (Dioxygen)IBA 12/2015 - 07/2014
2	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 10/2015 - 07/2014
2	N-Methylaspartate (NMDA)IBA 06/2014 - 08/2003
2	Adenosine Triphosphatases (ATPase)IBA 06/2014 - 01/2011
2	Therapeutic UsesIBA 01/2014 - 09/2010
2	Thiobarbituric Acid Reactive SubstancesIBA 08/2012 - 09/2007
2	Anticonvulsants (Antiepileptic Drugs)IBA 12/2011 - 08/2004
2	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 12/2011 - 10/2010
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2011 - 08/2003
2	Phosphopyruvate Hydratase (Enolase)IBA 06/2011 - 08/2006
2	PurinesIBA 02/2011 - 05/2006
2	GuanineIBA 02/2011 - 05/2006
2	Pilocarpine (Ocusert)FDA LinkGeneric 01/2011 - 05/2008
2	NucleotidasesIBA 10/2010 - 07/2007
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 10/2010 - 04/2010
2	BombesinIBA 02/2004 - 07/2003
1	MelatoninIBA 11/2022
1	Methylmalonic AcidIBA 11/2022
1	Nerve Growth Factors (Neurotrophins)IBA 08/2022
1	Antimalarials (Antimalarial Agents)IBA 01/2022
1	Chloroquine (Aralen)FDA LinkGeneric 01/2022
1	Diphtheria-Tetanus VaccineIBA 01/2022
1	Amyloid (Amyloid Fibrils)IBA 04/2021
1	VaccinesIBA 01/2021
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 01/2021
1	Uric Acid (Urate)IBA 01/2021
1	ProteomeIBA 01/2021
1	SaponinsIBA 01/2021
1	Purinergic Receptors (Receptors, Purine)IBA 01/2021
1	ApigeninIBA 01/2020
1	FlavonoidsIBA 01/2020
1	Lysine (L-Lysine)FDA Link 10/2019
1	AcidsIBA 10/2019

Therapy/Procedure

2	Ligation 01/2018 - 08/2012
2	Traditional Medicine (Folk Remedies) 01/2017 - 12/2016
1	Immunomodulation 01/2022