Derya R Shimshek Selected Research

Synucleinopathies

12/2020	Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions.
1/2015	Formaldehyde-fixed brain tissue from spontaneously ill α-synuclein transgenic mice induces fatal α-synucleinopathy in transgenic hosts.
4/2010	The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy.

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Derya R Shimshek Research Topics

Disease

15	Parkinson Disease (Parkinson's Disease) 11/2021 - 04/2010
10	Alzheimer Disease (Alzheimer's Disease) 12/2020 - 09/2015
5	Neuroinflammatory Diseases 02/2023 - 01/2013
3	Demyelinating Diseases (Demyelinating Disease) 02/2023 - 01/2018
3	Synucleinopathies 12/2020 - 04/2010
3	Dementia (Dementias) 01/2019 - 09/2015
2	Gliosis 02/2023 - 01/2012
2	Disease Progression 11/2021 - 01/2016
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2020 - 01/2016
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2016 - 01/2014
1	Parkinsonian Disorders (Parkinsonism) 01/2022
1	Multiple Sclerosis 01/2021
1	Amyloidosis 12/2020
1	Memory Disorders (Memory Loss) 12/2020
1	Familial Cerebral Amyloid Angiopathy 10/2019
1	Amyloid Plaque 11/2018
1	Asymptomatic Diseases 11/2018
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2018
1	Neoplasms (Cancer) 01/2014
1	Leprosy (Hansen's Disease) 01/2014
1	Huntington Disease (Huntington's Disease) 01/2012
1	Seizures (Absence Seizure) 11/2004

Drug/Important Bio-Agent (IBA)

11	Phosphotransferases (Kinase)IBA 01/2022 - 11/2011
10	Amyloid (Amyloid Fibrils)IBA 10/2019 - 01/2014
9	Leucine (L-Leucine)FDA Link 11/2021 - 11/2011
9	Proteins (Proteins, Gene)FDA Link 01/2019 - 11/2011
8	SynucleinsIBA 11/2021 - 01/2011
3	CuprizoneIBA 02/2023 - 01/2018
3	EnzymesIBA 01/2019 - 06/2017
2	NB-360IBA 01/2019 - 09/2015
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2019 - 02/2016
1	ChemokinesIBA 02/2023
1	CytokinesIBA 02/2023
1	ParvalbuminsIBA 12/2020
1	Amyloid beta-PeptidesIBA 12/2020
1	Peptides (Polypeptides)IBA 10/2019
1	UmibecestatIBA 11/2018
1	4- (2- (2- hydroxycyclohexylamino)benzothiazol- 6- yloxy)pyridine- 2- carboxylic acid methylamideIBA 01/2018
1	Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Formaldehyde (Formol)FDA Link 01/2015
1	Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA 01/2012
1	Leucine-Rich Repeat ProteinsIBA 01/2012
1	UbiquitinIBA 01/2012
1	Molecular Chaperones (Chaperone, Molecular)IBA 04/2010
1	alpha-SynucleinIBA 04/2010
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 04/2010
1	AMPA Receptors (AMPA Receptor)IBA 11/2004
1	glutamate receptor type BIBA 11/2004
1	Glutamate Receptors (Glutamate Receptor)IBA 11/2004

Therapy/Procedure

5	Therapeutics 11/2021 - 01/2016
1	Precision Medicine 01/2019
1	Immunotherapy 01/2016