Qi Shi Selected Research

Prion Proteins

8/2022	Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells - China's Studies.
1/2022	Case Report: Genetic Creutzfeldt-Jakob Disease With a G114V Mutation and One Octapeptide Repeat Deletion as a Mimic of Frontotemporal Dementia.
11/2021	Genetic Prion Disease: Insight from the Features and Experience of China National Surveillance for Creutzfeldt-Jakob Disease.
10/2021	Accumulation of Prion and Abnormal Prion Protein Induces Hyperphosphorylation of α-Synuclein in the Brain Tissues from Prion Diseases and in the Cultured Cells.
9/2021	Analysis of the Electrophoretic Profiles of Prion Protein in Carcinous and Pericarcinous Lysates of Six Different Types of Cancers.
12/2018	Evaluation of the effect of various main elements on the PrPSc detection by real-time quaking-induced conversion assay.
1/2017	Protein Misfolding Cyclic Amplification Cross-Species Products of Mouse-Adapted Scrapie Strain 139A and Hamster-Adapted Scrapie Strain 263K with Brain and Muscle Tissues of Opposite Animals Generate Infectious Prions.
10/2016	Proteomic Analyses for the Global S-Nitrosylated Proteins in the Brain Tissues of Different Human Prion Diseases.
2/2016	Remarkable impairment of Wnt/β-catenin signaling in the brains of the mice infected with scrapie agents.
2/2016	Expression of prion protein is closely associated with pathological and clinical progression and abnormalities of p53 in head and neck squamous cell carcinomas.

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Qi Shi Research Topics

Disease

67	Prion Diseases (Transmissible Spongiform Encephalopathies) 04/2024 - 09/2006
54	Neoplasms (Cancer) 01/2024 - 08/2010
45	Scrapie 04/2024 - 01/2008
43	Infections 04/2024 - 09/2011
24	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023 - 09/2006
23	Inflammation (Inflammations) 04/2024 - 02/2009
19	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2023 - 10/2008
12	Neoplasm Metastasis (Metastasis) 12/2023 - 02/2008
11	Pain (Aches) 06/2024 - 06/2010
11	Osteoporosis 03/2024 - 06/2010
10	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 01/2016
10	Rheumatoid Arthritis 10/2023 - 03/2018
10	Arthritis (Polyarthritis) 01/2022 - 03/2018
9	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 09/2006
8	Sporadic Creutzfeldt-Jakob Disease 01/2024 - 11/2013
8	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 02/2016
7	Carcinogenesis 12/2023 - 10/2016
7	Radiculopathy (Radiculopathy, Cervical) 08/2017 - 11/2003
6	Chronic Obstructive Pulmonary Disease (COPD) 04/2024 - 01/2017
6	Esophageal Squamous Cell Carcinoma 12/2023 - 08/2015
6	Acquired CJD 01/2018 - 12/2008
6	Intervertebral Disc Degeneration 01/2014 - 02/2007
5	Experimental Arthritis 04/2024 - 01/2018
5	Hemorrhage 03/2024 - 01/2020
5	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 02/2008
5	Fatal Familial Insomnia 01/2018 - 10/2008
5	Urinary Bladder Neoplasms (Bladder Cancer) 04/2016 - 01/2014
4	Gliosis 08/2022 - 11/2013
4	Mitochondrial Diseases (Mitochondrial Disease) 05/2022 - 01/2012
4	Asthma (Bronchial Asthma) 01/2022 - 08/2016
4	Parkinson Disease (Parkinson's Disease) 10/2021 - 03/2013
4	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2014
4	Hypoxia (Hypoxemia) 01/2020 - 08/2012
4	Sleep Initiation and Maintenance Disorders (Insomnia) 02/2019 - 11/2013
4	Osteosarcoma (Osteogenic Sarcoma) 11/2017 - 07/2015
4	Neuroblastoma 12/2013 - 09/2006
3	Osteoporotic Fractures 03/2024 - 11/2019
3	Bone Fractures (Bone Fracture) 03/2024 - 01/2013
3	Wounds and Injuries (Trauma) 01/2024 - 01/2017
3	Esophageal Neoplasms (Esophageal Cancer) 12/2023 - 01/2020
3	Neuroinflammatory Diseases 10/2023 - 01/2017
3	Myoclonus (Nocturnal Myoclonus) 01/2023 - 01/2018
3	Neck Pain (Cervicalgia) 01/2023 - 01/2010
3	Nausea 01/2023 - 01/2016
3	Vomiting 01/2023 - 01/2016
3	Stomach Neoplasms (Stomach Cancer) 01/2022 - 08/2021
3	Disease Progression 10/2021 - 08/2015
3	Amyloid Plaque 09/2017 - 07/2010

Drug/Important Bio-Agent (IBA)

60	Proteins (Proteins, Gene)FDA Link 04/2024 - 09/2006
52	PrionsIBA 04/2024 - 09/2007
25	Biomarkers (Surrogate Marker)IBA 04/2024 - 07/2010
25	Prion ProteinsIBA 08/2022 - 09/2006
9	CytokinesIBA 02/2023 - 06/2010
9	Codon (Codons)IBA 11/2021 - 12/2008
8	Protein Isoforms (Isoforms)IBA 01/2019 - 09/2006
8	PrPSc ProteinsIBA 01/2017 - 10/2008
6	Therapeutic UsesIBA 04/2024 - 02/2009
6	14-3-3 Proteins (14-3-3 Protein)IBA 01/2023 - 04/2010
6	CateninsIBA 01/2022 - 09/2012
6	Endopeptidase K (Proteinase K)IBA 09/2021 - 07/2008
6	Phosphotransferases (Kinase)IBA 01/2021 - 09/2012
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2020 - 02/2008
5	Huang QiIBA 04/2024 - 01/2011
5	EnzymesIBA 04/2024 - 10/2010
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2023 - 02/2014
5	MicroRNAs (MicroRNA)IBA 01/2019 - 08/2014
5	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2018 - 03/2013
4	SmokeIBA 04/2024 - 07/2017
4	LipopolysaccharidesIBA 04/2024 - 07/2017
4	Interleukin-6 (Interleukin 6)IBA 01/2024 - 07/2017
4	Messenger RNA (mRNA)IBA 01/2022 - 02/2007
4	CollagenIBA 01/2020 - 02/2007
4	tau Proteins (tau Protein)IBA 01/2016 - 04/2009
4	Amino Acids FDA Link 01/2016 - 01/2009
4	AntibodiesIBA 08/2015 - 04/2009
3	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 05/2010
3	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2024 - 09/2017
3	Lactic Acid (Lactate)FDA LinkGeneric 12/2023 - 08/2016
3	LigandsIBA 09/2023 - 02/2014
3	Docetaxel (Taxotere)FDA Link 01/2023 - 10/2017
3	Methotrexate (Mexate)FDA LinkGeneric 01/2023 - 03/2018
3	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2022 - 01/2020
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 03/2010
3	ResveratrolIBA 01/2021 - 10/2016
3	Complement System Proteins (Complement)IBA 02/2020 - 12/2015
3	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2020 - 10/2016
3	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 11/2015
3	Methionine (L-Methionine)FDA Link 01/2018 - 12/2008
3	polyphyllin IIBA 01/2018 - 07/2015
3	Transcription Factors (Transcription Factor)IBA 11/2017 - 08/2012
3	Factor V (Coagulation Factor V)IBA 08/2017 - 08/2014
3	Valine (L-Valine)FDA Link 10/2016 - 05/2013

Therapy/Procedure

19	Therapeutics 06/2024 - 01/2014
13	Chinese Traditional Medicine (Traditional Chinese Medicine) 09/2023 - 03/2005
13	Drug Therapy (Chemotherapy) 01/2023 - 01/2014
4	Immunotherapy 01/2024 - 01/2021
4	Radiotherapy 01/2019 - 01/2014
3	Musculoskeletal Manipulations (Manipulative Therapy) 06/2024 - 08/2017
3	Sutures (Suture) 07/2023 - 01/2020
3	Aftercare (After-Treatment) 10/2022 - 11/2012