Chao Shang Selected Research

Neoplasms (Cancer)

2/2024	AGCM-22, a novel cetuximab-based EGFR-targeting antibody-drug-conjugate with highly selective anti-glioblastoma efficacy.
11/2023	Role and clinical significance of immunogenic cell death biomarkers in chemoresistance and immunoregulation of head and neck squamous cell carcinoma.
10/2023	A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo.
8/2023	A novel oncogene trigger transposable element derived-1 promotes oral squamous cell carcinoma progression via evoking immune inhibition.
5/2023	CD44 occurring alternative splicing promotes cisplatin resistance and evokes tumor immune response in oral squamous cell carcinoma cells.
1/2023	CXC chemokine ligand-10 promotes the accumulation of monocyte-like myeloid-derived suppressor cells by activating p38 MAPK signaling under tumor conditions.
10/2022	Apoptin Inhibits Glycolysis and Regulates Autophagy by Targeting Pyruvate Kinase M2 (PKM2) in Lung Cancer A549 Cells.
10/2022	The downregulation of type I IFN signaling in G-MDSCs under tumor conditions promotes their development towards an immunosuppressive phenotype.
1/2022	Apoptin mediates mitophagy and endogenous apoptosis by regulating the level of ROS in hepatocellular carcinoma.
1/2022	CXCL10 conditions alveolar macrophages within the premetastatic niche to promote metastasis.

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Chao Shang Research Topics

Disease

42	Neoplasms (Cancer) 02/2024 - 04/2005
12	Glioma (Gliomas) 01/2021 - 12/2014
9	Glioblastoma (Glioblastoma Multiforme) 02/2024 - 06/2012
7	Carcinoma (Carcinomatosis) 01/2018 - 03/2007
6	Endometrial Neoplasms (Endometrial Cancer) 01/2019 - 07/2011
5	Squamous Cell Carcinoma of Head and Neck 11/2023 - 04/2012
5	Neoplasm Metastasis (Metastasis) 08/2014 - 04/2005
4	Infections 04/2024 - 09/2020
4	COVID-19 01/2023 - 01/2021
3	Lung Neoplasms (Lung Cancer) 10/2022 - 09/2014
3	Breast Neoplasms (Breast Cancer) 11/2021 - 01/2021
3	Stomach Neoplasms (Stomach Cancer) 01/2016 - 04/2005
2	Liver Neoplasms (Liver Cancer) 01/2022 - 01/2020
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2020 - 06/2010
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2020 - 01/2018
2	Carcinogenesis 04/2018 - 02/2006
2	Transitional Cell Carcinoma 01/2017 - 03/2016
2	Ovarian Neoplasms (Ovarian Cancer) 08/2014 - 03/2013
2	Laryngeal Neoplasms (Laryngeal Cancer) 06/2010 - 06/2007
1	Colitis 11/2023
1	Dysbiosis 11/2023
1	Ulcerative Colitis 11/2023
1	Mouth Neoplasms (Oral Cancer) 04/2023
1	Hepatitis B 01/2023
1	Alzheimer Disease (Alzheimer's Disease) 03/2022
1	Adenocarcinoma of Lung 01/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Inflammation (Inflammations) 12/2021
1	Type 2 Diabetes Mellitus (MODY) 11/2021
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021
1	Viral Pneumonia 01/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Severe Acute Respiratory Syndrome 01/2021
1	Compression Fractures (Compression Fracture) 09/2020

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 04/2024 - 06/2007
14	Long Noncoding RNAIBA 03/2022 - 01/2016
10	Biomarkers (Surrogate Marker)IBA 11/2023 - 06/2015
8	MicroRNAs (MicroRNA)IBA 04/2018 - 01/2012
6	Messenger RNA (mRNA)IBA 03/2022 - 06/2010
6	Small Interfering RNA (siRNA)IBA 04/2018 - 04/2005
5	EnzymesIBA 10/2022 - 06/2012
5	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2020 - 01/2016
4	Gentian Violet (Violet, Crystal)FDA Link 10/2022 - 01/2020
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 06/2016
3	Temozolomide (Temodar)FDA LinkGeneric 02/2024 - 01/2018
3	Sincalide FDA Link 10/2022 - 01/2021
3	Gemcitabine FDA Link 01/2022 - 01/2018
3	Cadherins (E-Cadherin)IBA 01/2021 - 04/2005
3	CateninsIBA 04/2018 - 07/2017
2	Cisplatin (Platino)FDA LinkGeneric 05/2023 - 04/2023
2	bafilomycin A1IBA 01/2023 - 01/2021
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2020
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 09/2012
2	Antisense RNA (Anti-Sense RNA)IBA 01/2019 - 01/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2018 - 01/2018
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 04/2024
1	Red Fluorescent ProteinIBA 03/2024
1	Immunoconjugates (Immunoconjugate)IBA 02/2024
1	antiglomerular basement membrane antibodyIBA 02/2024
1	AntibodiesIBA 02/2024
1	ErbB Receptors (EGF Receptor)IBA 02/2024
1	Cetuximab (Erbitux)FDA Link 02/2024
1	CytokinesIBA 11/2023
1	peimisineIBA 11/2023
1	Immune Checkpoint InhibitorsIBA 11/2023
1	Adenosine Triphosphate (ATP)IBA 11/2023
1	SB 743921IBA 10/2023
1	DNA Transposable Elements (Element, IS)IBA 08/2023
1	Interleukin-17 (Interleukin 17)IBA 04/2023
1	CXC ChemokinesIBA 01/2023
1	p38 Mitogen-Activated Protein KinasesIBA 01/2023
1	Virus-Like Particle VaccinesIBA 01/2023
1	EpitopesIBA 01/2023
1	Pyruvate KinaseIBA 10/2022
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 10/2022
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2022
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 01/2022
1	Apoptosis Regulatory ProteinsIBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 12/2021
1	4-phenylbutyric acid (Buphenyl)FDA Link 12/2021
1	Metformin (Glucophage)FDA LinkGeneric 11/2021
1	Mitochondrial Permeability Transition PoreIBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	Chloroquine (Aralen)FDA LinkGeneric 01/2021
1	SuspensionsIBA 01/2021
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021
1	Glutamic Acid (Glutamate)FDA Link 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	Polycomb Repressive Complex 1IBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 10/2020
1	Competitive Endogenous RNAIBA 10/2020
1	Bone Cements (Bone Glue)IBA 09/2020
1	Sertraline (Zoloft)FDA LinkGeneric 01/2020
1	Pregnanolone (Allopregnanolone)IBA 01/2020
1	gamma-Aminobutyric Acid (GABA)IBA 01/2020

Therapy/Procedure

13	Drug Therapy (Chemotherapy) 02/2024 - 01/2015
10	Therapeutics 02/2024 - 04/2012
1	Immunotherapy 11/2023
1	Vertebroplasty 09/2020