Barbara Serafini Selected Research

Multiple Sclerosis

10/2022	EBV as the 'gluten of MS' hypothesis: Bypassing autoimmunity.
1/2020	Connecting Immune Cell Infiltration to the Multitasking Microglia Response and TNF Receptor 2 Induction in the Multiple Sclerosis Brain.
12/2019	Megalencephalic Leukoencephalopathy with Subcortical Cysts Protein-1 (MLC1) Counteracts Astrocyte Activation in Response to Inflammatory Signals.
1/2018	Transcriptional profile and Epstein-Barr virus infection status of laser-cut immune infiltrates from the brain of patients with progressive multiple sclerosis.
1/2018	Epstein-Barr virus-associated immune reconstitution inflammatory syndrome as possible cause of fulminant multiple sclerosis relapse after natalizumab interruption.
1/2017	Massive intracerebral Epstein-Barr virus reactivation in lethal multiple sclerosis relapse after natalizumab withdrawal.
3/2015	Epstein-Barr virus genetic variants are associated with multiple sclerosis.
7/2013	Radioactive in situ hybridization for Epstein-Barr virus-encoded small RNA supports presence of Epstein-Barr virus in the multiple sclerosis brain.
1/2013	Increased CD8+ T cell response to Epstein-Barr virus lytic antigens in the active phase of multiple sclerosis.
2/2011	CD161(high)CD8+T cells bear pathogenetic potential in multiple sclerosis.

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Barbara Serafini Research Topics

Disease

18	Multiple Sclerosis 10/2022 - 04/2004
5	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 07/2008 - 09/2002
3	Epstein-Barr Virus Infections 01/2018 - 07/2010
2	Demyelinating Diseases (Demyelinating Disease) 01/2020 - 12/2019
2	Megalencephalic leukoencephalopathy with subcortical cysts 12/2019 - 03/2010
2	Inflammation (Inflammations) 01/2017 - 07/2008
2	Rheumatoid Arthritis 09/2013 - 02/2011
2	Neuroinflammatory Diseases 07/2008 - 01/2003
1	Celiac Disease (Celiac Sprue) 10/2022
1	Gliosis 12/2019
1	Immune Reconstitution Inflammatory Syndrome 01/2018
1	Osteoarthritis 09/2013
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 09/2013
1	Tertiary Lymphoid Structures 07/2008
1	Disease Progression 10/2006
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 08/2005
1	Infections 08/2005
1	Arthritis (Polyarthritis) 08/2004

Drug/Important Bio-Agent (IBA)

4	AntigensIBA 10/2022 - 02/2006
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2006
4	ChemokinesIBA 07/2008 - 01/2003
3	RNA (Ribonucleic Acid)IBA 01/2020 - 07/2013
3	CytokinesIBA 01/2020 - 12/2008
2	Membrane Proteins (Integral Membrane Proteins)IBA 12/2019 - 03/2010
2	Natalizumab (Tysabri)FDA Link 01/2018 - 01/2017
2	AntibodiesIBA 09/2013 - 07/2010
2	InterferonsIBA 02/2011 - 05/2008
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2010 - 12/2008
2	Oligoclonal BandsIBA 09/2008 - 04/2004
1	Glutens (Glutelin)IBA 10/2022
1	Antiviral Agents (Antivirals)IBA 10/2022
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2020
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2020
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2020
1	LipidsIBA 01/2018
1	Nuclear Antigens (Extractable Nuclear Antigens)IBA 03/2015
1	AutoantigensIBA 09/2013
1	DNA (Deoxyribonucleic Acid)IBA 09/2013
1	Peptides (Polypeptides)IBA 09/2013
1	NK Cell Lectin-Like Receptor Subfamily BIBA 02/2011
1	B-Cell Activating FactorIBA 07/2010
1	TWEAK ReceptorIBA 12/2008
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 12/2008
1	Interferon-betaIBA 05/2008
1	Immunoglobulins (Immunoglobulin)IBA 10/2006
1	Lymphotoxin-alpha (Lymphotoxin)IBA 10/2006
1	Lymphotoxin beta ReceptorIBA 10/2006
1	PrionsIBA 08/2005
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 02/2003
1	Chemokine CCL22IBA 09/2002

Therapy/Procedure

1	Lasers (Laser) 01/2018
1	Therapeutics 05/2008