Jogchum Plat Selected Research

Esters

1/2022	Plant stanol esters might optimise the immune response and improve the SARS-CoV-2/COVID-19 vaccine efficacy in overweight and obese subjects.
1/2020	Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease.
2/2016	Dietary plant stanol ester consumption improves immune function in asthma patients: results of a randomized, double-blind clinical trial.
10/2015	Effects of Dietary Plant Sterols and Stanol Esters with Low- and High-Fat Diets in Chronic and Acute Models for Experimental Colitis.
1/2014	Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans.
12/2009	Plant stanol esters lower serum triacylglycerol concentrations via a reduced hepatic VLDL-1 production.
6/2009	A plant stanol yogurt drink alone or combined with a low-dose statin lowers serum triacylglycerol and non-HDL cholesterol in metabolic syndrome patients.
5/2007	Customary use of plant sterol and plant stanol enriched margarine is associated with changes in serum plant sterol and stanol concentrations in humans.

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Jogchum Plat Research Topics

Disease

34	Inflammation (Inflammations) 01/2023 - 09/2005
20	Overweight 05/2024 - 09/2005
20	Cardiovascular Diseases (Cardiovascular Disease) 05/2022 - 06/2009
16	Insulin Resistance 12/2023 - 01/2009
13	Obesity 01/2024 - 01/2016
13	Weight Loss (Weight Reduction) 04/2022 - 12/2007
11	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2023 - 09/2006
9	Coronary Disease (Coronary Heart Disease) 01/2021 - 09/2005
8	Atherosclerosis 02/2023 - 02/2014
4	Asthma (Bronchial Asthma) 01/2024 - 01/2012
4	Alcoholic Fatty Liver 01/2020 - 01/2013
4	Macular Degeneration (Age-Related Maculopathy) 01/2017 - 06/2009
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2015 - 05/2007
3	Non-alcoholic Fatty Liver Disease 11/2022 - 02/2008
3	Liver Diseases (Liver Disease) 01/2020 - 10/2016
3	Fatty Liver 01/2017 - 01/2013
3	Colitis 10/2015 - 05/2007
2	Weight Gain 09/2023 - 08/2015
2	Abdominal Obesity 01/2022 - 01/2019
2	Hyperlipidemias (Hyperlipidemia) 10/2021 - 01/2019
2	Cognitive Dysfunction 06/2021 - 08/2020
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 07/2015
2	Chorioamnionitis 05/2020 - 04/2019
2	Infections 05/2020 - 05/2008
2	Hypertension (High Blood Pressure) 01/2018 - 04/2017
2	Type 2 Diabetes Mellitus (MODY) 11/2017 - 02/2009
2	Fibrosis (Cirrhosis) 10/2016 - 08/2015
2	Aortic Valve Stenosis (Aortic Stenosis) 07/2015 - 04/2014
2	Hypertriglyceridemia 12/2014 - 12/2009
2	Dyslipidemias (Dyslipidemia) 01/2011 - 10/2007
1	COVID-19 01/2024
1	Hepatitis A (Hepatitis, Infectious) 01/2024
1	Body Weight (Weight, Body) 09/2023
1	Prediabetic State (Prediabetes) 09/2023
1	Sitosterolemia 02/2023
1	Eczema 02/2022

Drug/Important Bio-Agent (IBA)

26	LipidsIBA 12/2023 - 12/2007
25	CholesterolIBA 01/2023 - 04/2006
21	Phytosterols (Plant Sterols)IBA 02/2023 - 07/2003
16	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 03/2010
11	Triglycerides (Triacylglycerol)IBA 10/2020 - 12/2007
10	Apolipoprotein A-I (Apolipoprotein A1)IBA 05/2022 - 06/2009
9	Lipoproteins (Lipoprotein)IBA 10/2023 - 04/2008
8	Insulin (Novolin)FDA Link 12/2023 - 03/2010
8	oxidized low density lipoproteinIBA 02/2023 - 09/2005
8	EstersIBA 01/2022 - 05/2007
8	LDL CholesterolIBA 10/2020 - 09/2005
6	HDL CholesterolIBA 01/2021 - 06/2009
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2016 - 09/2006
5	gamma-sitosterol (beta-sitosterol)IBA 05/2020 - 04/2006
5	Fatty Acids (Saturated Fatty Acids)IBA 10/2015 - 08/2008
4	NWT-03IBA 05/2024 - 04/2017
4	plant stanol esterIBA 01/2024 - 06/2009
4	Biomarkers (Surrogate Marker)IBA 11/2022 - 01/2017
4	Fish OilsIBA 01/2022 - 12/2007
4	Retinaldehyde (Retinal)IBA 10/2020 - 01/2017
4	NF-kappa B (NF-kB)IBA 07/2020 - 08/2007
3	Proteins (Proteins, Gene)FDA Link 01/2024 - 04/2006
3	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 04/2019
3	lathosterolIBA 04/2022 - 07/2015
3	campesterolIBA 04/2022 - 04/2019
3	Cholestanol (Coprostanol)IBA 04/2022 - 07/2015
3	Cell Adhesion MoleculesIBA 01/2022 - 08/2007
3	CytokinesIBA 01/2021 - 11/2010
3	stigmastanolIBA 10/2018 - 01/2012
3	LuteinIBA 01/2017 - 01/2014
3	Dextrans (Dextran)FDA Link 10/2015 - 05/2007
2	Egg ProteinsIBA 12/2023 - 10/2023
2	EmulsionsIBA 11/2022 - 01/2020
2	Palmitic Acid (Hexadecanoic Acid)IBA 10/2021 - 03/2010
2	stearic acid (magnesium stearate)FDA LinkGeneric 10/2021 - 01/2021
2	HDL LipoproteinsIBA 01/2021 - 07/2020
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2020 - 09/2014
2	C-PeptideIBA 10/2020 - 01/2017
2	27-hydroxycholesterolIBA 01/2020 - 01/2013
2	Vitamin E FDA LinkGeneric 01/2020 - 11/2017
2	TheobromineIBA 04/2019 - 01/2018
2	Cholesterol Ester Transfer ProteinsIBA 01/2018 - 06/2009
2	ResveratrolIBA 12/2017 - 01/2015
2	Cathepsin DIBA 01/2017 - 12/2016
2	MagnesiumIBA 01/2017 - 05/2016
2	Hydroxyproline (4 Hydroxyproline)IBA 10/2016 - 08/2015
2	SodiumIBA 10/2015 - 05/2007
2	Apolipoproteins E (ApoE)IBA 08/2015 - 04/2006
2	ApolipoproteinsIBA 08/2015 - 09/2006
2	PalmitatesIBA 04/2011 - 01/2009
2	Rosiglitazone (Avandia)FDA Link 02/2009 - 05/2007
2	beta-GlucansIBA 05/2008 - 02/2005
1	Immunoglobulin M (IgM)IBA 01/2024
1	Immunoglobulin G (IgG)IBA 01/2024
1	AntigensIBA 01/2024
1	maltodextrinIBA 12/2023
1	LipopolysaccharidesIBA 01/2023
1	MicroRNAs (MicroRNA)IBA 11/2022
1	StigmasterolIBA 02/2022
1	SterolsIBA 02/2022
1	LanosterolIBA 02/2022
1	SelectinsIBA 01/2022

Therapy/Procedure

2	Parenteral Nutrition 11/2022 - 01/2020
2	Therapeutics 01/2021 - 02/2014