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Catarina Moreira Pinho Selected Research

Alzheimer Disease (Alzheimer's Disease)

9/2023Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models.
1/2016Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production.
10/2014Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation.
7/2014Mitochondrial import and degradation of amyloid-β peptide.
5/2013Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.
12/2012In vitro oxidative inactivation of human presequence protease (hPreP).
1/2012Biochemical studies of poly-T variants in the Alzheimer's disease associated TOMM40 gene.
1/2011Decreased proteolytic activity of the mitochondrial amyloid-β degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria.

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Catarina Moreira Pinho Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
09/2023 - 01/2011
2Mitochondrial Diseases (Mitochondrial Disease)
10/2014 - 07/2014
1Disease Progression
09/2023
1Neuroblastoma
05/2013

Drug/Important Bio-Agent (IBA)

5Amyloid (Amyloid Fibrils)IBA
09/2023 - 01/2011
5Peptides (Polypeptides)IBA
09/2023 - 01/2011
2Proteins (Proteins, Gene)FDA Link
09/2023 - 01/2016
1Presenilin-2IBA
05/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2012
1Poly TIBA
01/2012
1ApolipoproteinsIBA
01/2012
1Apolipoproteins E (ApoE)IBA
01/2012
1EnzymesIBA
01/2011