Juan M Pascual Selected Research

Lactic Acid (Lactate)

11/2012	Metabolism of [U-13 C]glucose in human brain tumors in vivo.
10/2012	Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.

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Juan M Pascual Research Topics

Disease

11	Seizures (Absence Seizure) 01/2023 - 10/2002
9	Glut1 Deficiency Syndrome 01/2023 - 10/2002
8	Epilepsy (Aura) 01/2023 - 04/2007
7	Brain Diseases (Brain Disorder) 08/2023 - 06/2008
6	Neoplasms (Cancer) 01/2023 - 09/2011
5	Microcephaly 10/2012 - 10/2002
4	Glioblastoma (Glioblastoma Multiforme) 11/2012 - 09/2011
3	Glioma (Gliomas) 11/2021 - 09/2011
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 05/2011
3	Brain Neoplasms (Brain Tumor) 11/2012 - 09/2011
2	Dementia (Dementias) 01/2023 - 01/2023
2	Ketosis 01/2023 - 01/2023
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2016
2	Pyruvate Dehydrogenase Complex Deficiency Disease 01/2019 - 01/2015
2	Ataxia (Dyssynergia) 04/2006 - 01/2005
1	Adenocarcinoma of Lung 01/2023
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2023
1	Absence Epilepsy (Childhood Absence Epilepsy) 01/2023
1	Tauopathies 01/2020
1	Amyloidosis 01/2020
1	MELAS Syndrome (Syndrome, MELAS) 06/2017
1	Hepatolenticular Degeneration (Wilson's Disease) 01/2017
1	Rare Diseases (Rare Disease) 11/2015
1	Fatigue 02/2015
1	congenital fibrosis of the extraocular muscles 01/2014
1	Disease Progression 01/2014
1	Corneal Perforation 01/2014
1	Glycogen Storage Disease Type II (Pompe's Disease) 06/2013
1	Neoplasm Metastasis (Metastasis) 10/2012
1	Renal Cell Carcinoma (Grawitz Tumor) 10/2012
1	Altitude Sickness (Mountain Sickness) 10/2012
1	Ischemia 10/2012
1	Traumatic Brain Injuries (Traumatic Brain Injury) 10/2012
1	Kearns-Sayre Syndrome 05/2011
1	Necrosis 05/2011
1	Nervous System Diseases (Neurological Disorders) 05/2011
1	Neurologic Manifestations (Neurological Manifestations) 05/2011
1	Acute Hemorrhagic Leukoencephalitis (Hurst Syndrome) 05/2011
1	Deglutition Disorders (Dysphagia) 05/2007
1	Hypersensitivity (Allergy) 04/2007
1	Hypoglycemia (Reactive Hypoglycemia) 04/2007
1	Hyperinsulinism (Hyperinsulinemia) 04/2007
1	Gastroesophageal Reflux (GERD) 04/2007
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2006
1	Fanconi Syndrome (Syndrome, Fanconi) 05/2004

Drug/Important Bio-Agent (IBA)

18	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 05/2004
9	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 08/2023 - 10/2002
6	Glucose Transporter Type 1IBA 01/2023 - 04/2007
5	Proteins (Proteins, Gene)FDA Link 05/2022 - 09/2011
4	triheptanoinIBA 01/2023 - 02/2013
4	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2015 - 10/2012
3	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 05/2011
2	CarbohydratesIBA 01/2023 - 06/2013
2	CarbonIBA 01/2023 - 10/2022
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 05/2022 - 09/2011
2	Neurotransmitter Agents (Neurotransmitter)IBA 05/2022 - 10/2012
2	LipidsIBA 06/2017 - 01/2015
2	Glutamine (L-Glutamine)FDA Link 01/2015 - 06/2012
2	Lactic Acid (Lactate)FDA LinkGeneric 11/2012 - 10/2012
2	Oxygen (Dioxygen)IBA 11/2012 - 10/2012
2	SteroidsIBA 05/2007 - 04/2007
2	Fluticasone (Cutivate)FDA LinkGeneric 05/2007 - 04/2007
1	Acetazolamide (Diamox)FDA LinkGeneric 01/2023
1	KetonesIBA 01/2023
1	3-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA 01/2023
1	AMPA Receptors (AMPA Receptor)IBA 10/2022
1	AcidsIBA 10/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 05/2022
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	Pyruvic Acid (Pyruvate)IBA 01/2019
1	Mitochondrial DNA (mtDNA)IBA 06/2017
1	cupric chloride (copper(II) chloride)FDA Link 01/2017
1	CopperIBA 01/2017
1	EnzymesIBA 01/2016
1	Protein Kinase CIBA 06/2015
1	KinesinsIBA 01/2014
1	GlycogenIBA 06/2013
1	propionyl-coenzyme A (propionyl-CoA)IBA 02/2013
1	Deoxyglucose (2 Deoxy D glucose)IBA 11/2012
1	Glutamic Acid (Glutamate)FDA Link 10/2012
1	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 10/2012
1	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 10/2012
1	AminesIBA 10/2012
1	Amino Acids FDA Link 10/2012
1	gamma-Aminobutyric Acid (GABA)IBA 10/2012
1	Aminobutyrates (Aminobutyric Acid)IBA 10/2012
1	Protein Isoforms (Isoforms)IBA 10/2012
1	isocitric acid (isocitrate)IBA 01/2012
1	alpha-hydroxyglutarateIBA 01/2012
1	Nucleic AcidsIBA 09/2011
1	5,11-methenyltetrahydrohomofolateIBA 05/2011
1	Indicators and Reagents (Reagents)IBA 05/2011
1	Biotin (Vitamin H)FDA Link 05/2011
1	Folic Acid (Vitamin M)FDA LinkGeneric 05/2011
1	Immunoglobulin E (IgE)IBA 04/2007
1	AllergensIBA 04/2007
1	MonosaccharidesIBA 05/2004

Therapy/Procedure

6	Therapeutics 05/2022 - 10/2012
3	Ketogenic Diet 01/2023 - 02/2013
1	Penetrating Keratoplasty 01/2014