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Eleonora Pagnotta Selected Research

Neoplasms (Cancer)

3/2019Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1).
4/2013A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
2/2013Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver.
9/2012Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage.
4/2012Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect.
7/2008P53 oncosuppressor influences selection of genomic imbalances in response to ionizing radiations in human osteosarcoma cell line SAOS-2.
6/2006N-methylformamide and 9-hydroxystearic acid: two anti-proliferative and differentiating agents with different modes of action in colon cancer cells.
4/20069-Hydroxystearic acid interferes with EGF signalling in a human colon adenocarcinoma.

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Eleonora Pagnotta Research Topics

Disease

8Neoplasms (Cancer)
03/2019 - 04/2006
3Pain (Aches)
07/2022 - 01/2019
3Inflammation (Inflammations)
07/2022 - 06/2021
3Colonic Neoplasms (Colon Cancer)
06/2006 - 08/2005
2Colitis
07/2022 - 02/2022
2Hypersensitivity (Allergy)
07/2022 - 02/2022
1Reperfusion Injury
12/2023
1Ischemia
12/2023
1Peritonitis
12/2022
1Hyperalgesia
07/2022
1Visceral Pain
02/2022
1Arthritis (Polyarthritis)
02/2022
1Gliosis
02/2022
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
02/2022
1Infections
11/2021
1Body Weight (Weight, Body)
04/2021
1Obesity
04/2021
1Mycoses (Diseases, Fungus)
07/2019
1Pancreatic Neoplasms (Pancreatic Cancer)
03/2019
1Adenocarcinoma
03/2019
1Neuralgia (Stump Neuralgia)
01/2019
1Autolysis
12/2018
1Wounds and Injuries (Trauma)
05/2017
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2009
1Osteosarcoma (Osteogenic Sarcoma)
07/2008
1Genomic Instability
07/2008
1Carcinoma (Carcinomatosis)
08/2005
1Neuroblastoma
07/2003

Drug/Important Bio-Agent (IBA)

6GlucosinolatesIBA
02/2022 - 02/2013
4EnzymesIBA
12/2018 - 06/2006
3erucinIBA
12/2023 - 03/2019
3IsothiocyanatesIBA
04/2021 - 02/2013
39-hydroxystearic acidIBA
06/2006 - 08/2005
22,4-dinitrofluorobenzene sulfonic acidIBA
07/2022 - 02/2022
2AntioxidantsIBA
06/2021 - 04/2012
2glucoerucinIBA
04/2021 - 01/2019
2isothiocyanic acidIBA
03/2019 - 04/2012
2Proteins (Proteins, Gene)FDA Link
06/2009 - 07/2008
2Histone Deacetylase 1IBA
04/2006 - 08/2005
1mitochondrial K(ATP) channelIBA
12/2023
1CalciumIBA
12/2023
1LipopolysaccharidesIBA
12/2022
12,4-dinitrobenzenesulfonic acidIBA
07/2022
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
07/2022
1Therapeutic UsesIBA
07/2022
12,4-dinitrobenzeneIBA
02/2022
1Sulfonic AcidsIBA
02/2022
1Potassium Channels (Potassium Channel)IBA
02/2022
1Anti-Bacterial Agents (Antibiotics)IBA
11/2021
1fumagillinIBA
11/2021
1Glucose (Dextrose)FDA LinkGeneric
04/2021
1Hypoglycemic Agents (Hypoglycemics)IBA
04/2021
1allyl isothiocyanateIBA
07/2019
12,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)IBA
07/2019
1Phosphotransferases (Kinase)IBA
03/2019
1Antineoplastic Agents (Antineoplastics)IBA
03/2019
1Streptozocin (Streptozotocin)FDA Link
01/2019
1nasIBA
12/2018
1Glutathione Transferase (Glutathione S-Transferase)IBA
04/2013
1thioglucosidaseIBA
02/2013
1Histone Deacetylases (Histone Deacetylase)IBA
04/2012
1sulforaphaneIBA
04/2012
1LigandsIBA
06/2009
1DNA (Deoxyribonucleic Acid)IBA
07/2008
1methylformamideIBA
06/2006
1Epidermal Growth Factor (EGF)IBA
04/2006
1Growth InhibitorsIBA
08/2005
1AntibodiesIBA
07/2003

Therapy/Procedure

2Therapeutics
02/2022 - 06/2006
1Aftercare (After-Treatment)
05/2017
1Drug Therapy (Chemotherapy)
09/2012