Thomas Otto Selected Research

Therapeutics

5/2022	Molecular Diagnostic and Prognostication Assays for the Subtyping of Urinary Bladder Cancer Are on the Way to Illuminating Our Vision.
9/2017	Review of surgical implant procedures for male incontinence after radical prostatectomy according to IDEAL framework.
4/2016	Prostatic sarcoma of the Ewing family in a 33-year-old male - A case report and review of the literature.
4/2013	Combined treatment with pazopanib and vinflunine in patients with advanced urothelial carcinoma refractory after first-line therapy.
11/2012	Targeted agents in second-line bladder cancer therapy.
10/2011	Long-term response in advanced bladder cancer involving the use of temsirolimus and vinflunine after platin resistance.
1/2011	Vinflunine as second-line treatment in platin-resistant metastatic urothelial carcinoma: a review.
6/2010	Feasibility of sequential use of sunitinib and temsirolimus in advanced renal cell carcinoma.
5/2009	Experiences and practical conclusions concerning temsirolimus use and adverse event management in advanced renal cell carcinoma within a compassionate use program in Germany.
7/2002	Influence of pertussis toxin on superficial bladder carcinoma in rats.

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Thomas Otto Research Topics

Disease

17	Urinary Bladder Neoplasms (Bladder Cancer) 01/2023 - 07/2002
10	Neoplasms (Cancer) 12/2023 - 10/2011
4	Carcinoma (Carcinomatosis) 07/2022 - 07/2002
4	Renal Cell Carcinoma (Grawitz Tumor) 11/2012 - 05/2009
3	Prolapse 03/2017 - 10/2013
3	Transitional Cell Carcinoma 04/2013 - 07/2002
2	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 11/2017
2	Wounds and Injuries (Trauma) 01/2018 - 07/2012
2	Cystocele 03/2017 - 01/2017
2	Ureteral Obstruction 01/2017 - 08/2010
2	Urinary Incontinence 10/2013 - 07/2012
2	Disease Progression 10/2011 - 06/2010
1	Non-Muscle Invasive Bladder Neoplasms 12/2023
1	Inflammation (Inflammations) 05/2022
1	Erectile Dysfunction 01/2020
1	Cutaneous Fistula 01/2018
1	Stress Urinary Incontinence 09/2017
1	Carcinoma in Situ 05/2017
1	Ewing Sarcoma (Sarcoma, Ewing) 04/2016
1	Vesicovaginal Fistula 01/2015
1	Margins of Excision 08/2009
1	Exanthema (Rash) 05/2009
1	Hypercholesterolemia 05/2009
1	Asthenia 05/2009
1	Fatigue 05/2009
1	Hypertriglyceridemia 05/2009
1	Mucositis 05/2009
1	Pathologic Constriction (Stenosis) 07/2008
1	Hydronephrosis 07/2008
1	Fused Kidney 07/2008
1	Inguinal Hernia (Direct Inguinal Hernia) 06/2005

Drug/Important Bio-Agent (IBA)

6	Biomarkers (Surrogate Marker)IBA 12/2023 - 05/2017
3	Proteins (Proteins, Gene)FDA Link 12/2023 - 05/2017
3	PlatinumIBA 04/2013 - 01/2011
3	vinflunineIBA 04/2013 - 01/2011
3	temsirolimus FDA Link 10/2011 - 05/2009
2	Messenger RNA (mRNA)IBA 07/2022 - 11/2017
2	AcetyltransferasesIBA 01/2017 - 10/2011
1	Genetic Markers (Genetic Marker)IBA 01/2023
1	AntigensIBA 12/2022
1	Formaldehyde (Formol)FDA Link 07/2022
1	Phenobarbital (Luminal)FDA Link 07/2022
1	ParaffinIBA 07/2022
1	Cisplatin (Platino)FDA LinkGeneric 07/2022
1	ProcalcitoninIBA 05/2022
1	C-Reactive ProteinIBA 05/2022
1	68Ga-pentixaforIBA 11/2017
1	CXCR4 Receptors (CXCR4 Receptor)IBA 11/2017
1	polyvinylidene fluoride (PVDF)IBA 03/2017
1	N-acetyltransferase 1IBA 01/2017
1	CollagenIBA 03/2014
1	pazopanib FDA Link 04/2013
1	Insulin-Like Growth Factor Binding Protein 3IBA 02/2012
1	Insulin-Like PeptidesIBA 02/2012
1	MTOR InhibitorsIBA 01/2011
1	TOR Serine-Threonine KinasesIBA 01/2011
1	Sunitinib (Sutent)FDA Link 06/2010
1	CreatinineIBA 05/2009
1	LectinsIBA 07/2002
1	ButylhydroxybutylnitrosamineIBA 07/2002
1	Drinking WaterIBA 07/2002
1	Pertussis ToxinIBA 07/2002

Therapy/Procedure

10	Therapeutics 05/2022 - 07/2002
4	Prostatectomy (Retropubic Prostatectomy) 01/2020 - 08/2009
3	Drug Therapy (Chemotherapy) 07/2022 - 07/2002
3	Operative Surgical Procedures 01/2020 - 01/2015
2	Cystectomy 07/2022 - 10/2011
1	Neoadjuvant Therapy 07/2022
1	Length of Stay 05/2022
1	Biological Dressings 01/2018
1	Stents 01/2017
1	Hysterectomy 03/2014
1	Herniorrhaphy 10/2013
1	Sutures (Suture) 07/2012
1	Urinary Diversion (Ileal Conduit) 08/2010
1	Nephrectomy 07/2008
1	Kidney Transplantation 06/2005
1	Immunotherapy 07/2002