Gary R Ostroff Selected Research

Glucans

1/2024	A glucan-particle based tularemia subunit vaccine induces T-cell immunity and affords partial protection in an inhalation rat infection model.
2/2023	Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases.
1/2022	Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis.
1/2021	Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis.
1/2021	Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles.
1/2020	Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens.
11/2018	Glucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii Infection.
11/2018	Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung.
11/2017	Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species.
12/2015	Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.

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Gary R Ostroff Research Topics

Disease

13	Infections 01/2024 - 05/2009
6	Cryptococcosis 02/2023 - 12/2015
4	Coccidioidomycosis 01/2020 - 11/2012
3	Inflammation (Inflammations) 01/2021 - 04/2009
3	Neoplasms (Cancer) 11/2018 - 12/2003
2	Tularemia 01/2024 - 01/2018
2	Necrosis 01/2021 - 04/2009
2	Huntington Disease (Huntington's Disease) 10/2020 - 03/2014
2	Hookworm Infections (Hookworm Infection) 01/2019 - 01/2018
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2021
1	Pain (Aches) 01/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2020
1	Cryptococcal Meningitis 01/2020
1	Strongyloidiasis 11/2019
1	Melanoma (Melanoma, Malignant) 11/2018
1	Histoplasmosis 01/2018
1	HIV Infections (HIV Infection) 01/2016
1	Mycoses (Diseases, Fungus) 01/2011
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2009
1	Rheumatoid Arthritis 04/2009
1	Atherosclerosis 04/2009
1	Pneumonia (Pneumonitis) 07/2007
1	Lung Injury 07/2007

Drug/Important Bio-Agent (IBA)

15	VaccinesIBA 01/2024 - 05/2009
13	GlucansIBA 01/2024 - 07/2004
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2012
5	AntigensIBA 01/2022 - 12/2003
3	ChitinIBA 02/2023 - 07/2007
3	beta-GlucansIBA 05/2009 - 12/2003
2	Combined VaccinesIBA 01/2024 - 01/2020
2	Subunit VaccinesIBA 01/2024 - 01/2018
2	Polysaccharides (Glycans)IBA 11/2018 - 01/2011
2	CytokinesIBA 03/2014 - 04/2009
2	Small Interfering RNA (siRNA)IBA 03/2014 - 04/2009
2	Complement C3b (C3bi)IBA 07/2004 - 12/2003
2	Monoclonal AntibodiesIBA 07/2004 - 12/2003
1	AerosolsIBA 01/2024
1	RNA (Ribonucleic Acid)IBA 05/2023
1	Serum AlbuminIBA 05/2023
1	chitin deacetylaseIBA 01/2022
1	AutoantigensIBA 01/2021
1	Freund's AdjuvantIBA 01/2021
1	Peptides (Polypeptides)IBA 01/2021
1	mouse dectin-2IBA 01/2020
1	Fungal VaccinesIBA 01/2020
1	dectin 1IBA 01/2020
1	AnthelminticsIBA 11/2019
1	Cysteine Proteases (Cysteine Protease)IBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 11/2018
1	Macrophage Colony-Stimulating FactorIBA 11/2018
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2018
1	GalliumIBA 01/2016
1	EpitopesIBA 11/2012
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 11/2012
1	Immunologic Factors (Immunomodulators)IBA 05/2009
1	Messenger RNA (mRNA)IBA 04/2009
1	Phosphotransferases (Kinase)IBA 04/2009
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2009
1	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 04/2009
1	ZymosanIBA 07/2007
1	MannansIBA 07/2007
1	Complement System Proteins (Complement)IBA 07/2004
1	GangliosidesIBA 12/2003
1	Complement Receptors (Complement Receptor)IBA 12/2003
1	Hepatitis B e AntigensIBA 12/2003
1	Growth Factor ReceptorsIBA 12/2003
1	AntibodiesIBA 12/2003

Therapy/Procedure

2	Therapeutics 06/2011 - 04/2009