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Paul M O'Byrne Selected Research

Formoterol Fumarate (Oxis)

1/2022A patient decision aid for mild asthma: Navigating a new asthma treatment paradigm.
12/2021Positioning As-needed Budesonide-Formoterol for Mild Asthma: Effect of Prestudy Treatment in Pooled Analysis of SYGMA 1 and 2.
11/2021Reply to "As-needed budesonide-formoterol for adolescents with mild asthma: importance of lung function".
10/2021The cost-effectiveness of as-needed budesonide-formoterol versus low-dose inhaled corticosteroid maintenance therapy in patients with mild asthma in Canada.
1/2021Efficacy and Safety of As-Needed Budesonide-Formoterol in Adolescents with Mild Asthma.
1/2021Effect of a single day of increased as-needed budesonide-formoterol use on short-term risk of severe exacerbations in patients with mild asthma: a post-hoc analysis of the SYGMA 1 study.
1/2021The management of mild asthma.
1/2021Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies.
8/2020Inhaled corticosteroids/formoterol as a reliever in mild asthma.
1/2020What have we learnt about asthma control from trials of budesonide/formoterol as maintenance and reliever?
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Paul M O'Byrne Research Topics

Disease

169Asthma (Bronchial Asthma)
05/2024 - 01/2002
47Inflammation (Inflammations)
02/2023 - 01/2002
26Respiratory Hypersensitivity
01/2023 - 02/2002
18Eosinophilia
10/2023 - 07/2002
11Cough
11/2023 - 07/2015
8Chronic Obstructive Pulmonary Disease (COPD)
08/2015 - 08/2009
6Chronic Cough
02/2024 - 01/2020
6Allergic Rhinitis
11/2023 - 08/2002
5Airway Remodeling
01/2022 - 11/2002
3Hypersensitivity (Allergy)
11/2023 - 08/2003
3Pneumonia (Pneumonitis)
09/2015 - 07/2006
2Infections
01/2014 - 01/2012
2Rhinitis
03/2004 - 08/2002
1Neoplasms (Cancer)
04/2024
1Dysbiosis
04/2024
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
04/2024
1Tuberculosis (Tuberculoses)
01/2022
1Dysphonia (Spastic Dysphonia)
06/2021
1Bronchitis
01/2020
1Gastroesophageal Reflux (GERD)
01/2020
1Dyspnea (Shortness of Breath)
01/2020

Drug/Important Bio-Agent (IBA)

71AllergensIBA
04/2024 - 01/2002
60Adrenal Cortex Hormones (Corticosteroids)IBA
01/2022 - 07/2002
36Budesonide (Pulmicort)FDA LinkGeneric
01/2022 - 07/2002
27Formoterol Fumarate (Oxis)FDA Link
01/2022 - 01/2004
20CytokinesIBA
05/2024 - 07/2002
13SteroidsIBA
01/2020 - 01/2003
13Interleukin-5 (Interleukin 5)IBA
01/2016 - 07/2002
12Methacholine Chloride (Methacholine)FDA Link
01/2021 - 11/2002
11Interleukin-13IBA
11/2023 - 04/2004
10fluticasone furoateFDA Link
01/2020 - 06/2013
9Terbutaline (Brethaire)FDA LinkGeneric
12/2021 - 01/2005
9Immunoglobulin E (IgE)IBA
03/2017 - 08/2002
8Monoclonal AntibodiesIBA
02/2023 - 03/2009
8vilanterolIBA
01/2020 - 06/2013
7Bronchodilator Agents (Bronchodilators)IBA
12/2021 - 08/2015
7Formoterol Fumarate Drug Combination BudesonideFDA Link
12/2021 - 01/2004
73- (2- (4- azidobenzamidino)ethyl)- 5- hydroxyindole (SABA)IBA
10/2021 - 01/2005
7anti-IgE antibodiesIBA
01/2017 - 08/2002
6Leukotriene Antagonists (Leukotriene Receptor Antagonists)IBA
12/2021 - 01/2004
6Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2017 - 02/2007
5Thymic Stromal LymphopoietinIBA
02/2023 - 05/2014
5InterleukinsIBA
01/2023 - 07/2002
5Interleukin-33IBA
01/2023 - 06/2015
5Prednisone (Sone)FDA LinkGeneric
10/2020 - 04/2003
4AlarminsIBA
04/2024 - 01/2017
4Biomarkers (Surrogate Marker)IBA
11/2023 - 04/2009
4Capsaicin (Zostrix)FDA Link
01/2021 - 03/2017
4Fluticasone (Cutivate)FDA LinkGeneric
01/2020 - 02/2011
4GlucocorticoidsIBA
06/2018 - 01/2016
4Omalizumab (Xolair)FDA Link
01/2017 - 08/2002
3Immunoglobulins (Immunoglobulin)IBA
05/2024 - 06/2008
3tezepelumabIBA
02/2023 - 01/2023
3Salmeterol Xinafoate (Serevent)FDA Link
06/2014 - 02/2011
3Interleukin-18 ReceptorsIBA
01/2014 - 01/2013
3OvalbuminIBA
01/2012 - 07/2002
3LeukotrienesIBA
09/2009 - 07/2002
3Interleukin-4 (Interleukin 4)IBA
07/2006 - 04/2004
2benralizumabIBA
10/2023 - 01/2016
2AntibodiesIBA
10/2023 - 01/2014
2Immunoglobulin FragmentsIBA
02/2023 - 01/2023
2Histamine (Histamine Dihydrochloride)FDA Link
01/2021 - 05/2002
2Interleukin-17 (Interleukin 17)IBA
01/2018 - 01/2014
2Cholinergic Antagonists (Anticholinergics)IBA
08/2016 - 01/2012
2Humanized Monoclonal AntibodiesIBA
01/2016 - 01/2013
2mepolizumabIBA
01/2016 - 03/2009
2PeriostinIBA
01/2016 - 09/2015
2AntigensIBA
01/2014 - 01/2012
2Proteins (Proteins, Gene)FDA Link
01/2014 - 09/2002
2ciclesonideFDA Link
02/2011 - 08/2005
2Interleukin-10 (Interleukin 10)IBA
11/2008 - 02/2002
2Messenger RNA (mRNA)IBA
05/2008 - 09/2002
2montelukast (Singulair)FDA Link
09/2006 - 11/2002
2ChemokinesIBA
03/2005 - 08/2003
2pranlukastIBA
07/2004 - 04/2004
2Histamine Antagonists (Antihistamines)IBA
03/2004 - 07/2002
1neuromedin UIBA
04/2024
1NeuropeptidesIBA
04/2024
1Tryptases (Tryptase)IBA
11/2023
1GefapixantIBA
10/2023
1AerosolsIBA
01/2022
1VaccinesIBA
01/2022
1A 7 (A-7)IBA
06/2021
1Muscarinic AntagonistsIBA
06/2021
1Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
01/2021
1Antigen-Antibody Complex (Immune Complex)IBA
10/2020
1AutoantibodiesIBA
10/2020
1Enzyme Inhibitors (Inhibitors, Enzyme)IBA
01/2020
1Purinergic P2X3 ReceptorsIBA
01/2020
1prednylidene (Pred)IBA
01/2020

Therapy/Procedure

62Therapeutics
05/2024 - 07/2002
6Nebulizers and Vaporizers (Inhaler)
06/2021 - 01/2004
4Drug Therapy (Chemotherapy)
01/2017 - 10/2007
2Activities of Daily Living (ADL)
02/2024 - 11/2023
2Biological Therapy
02/2023 - 01/2023
2Aftercare (After-Treatment)
01/2021 - 11/2008
2Precision Medicine
01/2017 - 01/2016
2Emergency Treatment
01/2017 - 01/2009
1Airway Management
01/2022
1Language Therapy (Language Training)
01/2020