Victor Nizet Selected Research

Therapeutic Uses

3/2020	Azithromycin Exerts Bactericidal Activity and Enhances Innate Immune Mediated Killing of MDR Achromobacter xylosoxidans.
1/2018	Stabilization of Hypoxia-Inducible Factor-1 Alpha Augments the Therapeutic Capacity of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Pneumonia.
1/2018	The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia.
7/2015	Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens.
2/2004	Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections.

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Victor Nizet Research Topics

Disease

157	Infections 05/2024 - 01/2002
32	Inflammation (Inflammations) 04/2024 - 08/2003
25	Sepsis (Septicemia) 04/2024 - 06/2002
23	Bacteremia 03/2023 - 07/2011
22	Bacterial Infections (Bacterial Infection) 04/2024 - 01/2003
18	Hypoxia (Hypoxemia) 04/2015 - 03/2003
12	Communicable Diseases (Infectious Diseases) 05/2024 - 01/2006
12	Pneumonia (Pneumonitis) 12/2023 - 09/2011
7	Anthrax 01/2018 - 06/2008
7	Meningitis 11/2017 - 09/2003
6	Endocarditis 06/2023 - 02/2012
6	Septic Shock (Toxic Shock Syndrome) 01/2023 - 11/2002
5	Pharyngitis (Sore Throat) 04/2024 - 09/2011
5	Cystic Fibrosis (Mucoviscidosis) 01/2023 - 01/2017
5	Neoplasms (Cancer) 12/2020 - 01/2013
5	Necrotizing Fasciitis 01/2018 - 02/2006
4	Tonsillitis 04/2024 - 01/2019
4	Streptococcal Infections (Streptococcal Infection) 06/2020 - 08/2007
4	Muscle Cramp (Cramp) 01/2018 - 08/2009
4	Lung Injury 01/2018 - 03/2010
3	Urinary Tract Infections (Urinary Tract Infection) 02/2024 - 12/2018
3	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 10/2012
3	Thrombocytopenia (Thrombopenia) 11/2021 - 06/2008
3	Disease Progression 11/2021 - 07/2007
3	Weight Loss (Weight Reduction) 12/2020 - 02/2011
3	Arterial calcification of infancy 10/2018 - 06/2014
3	Hemolysis 01/2018 - 12/2002
3	Abscess 07/2016 - 07/2005
3	Anemia 12/2014 - 07/2007
3	Wounds and Injuries (Trauma) 03/2014 - 04/2007
2	Human Influenza (Influenza) 02/2024 - 01/2021
2	Superinfection 02/2024 - 01/2021
2	Virus Diseases (Viral Diseases) 02/2024 - 01/2018
2	COVID-19 02/2024 - 01/2022
2	Rheumatoid Arthritis 02/2024 - 10/2007

Drug/Important Bio-Agent (IBA)

40	Anti-Bacterial Agents (Antibiotics)IBA 04/2024 - 06/2002
23	CathelicidinsIBA 02/2024 - 01/2003
22	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2004
20	Virulence Factors (Pathogenicity Factors)IBA 04/2024 - 01/2002
16	CytokinesIBA 02/2024 - 06/2007
15	Antimicrobial PeptidesIBA 02/2024 - 01/2003
12	Transcription Factors (Transcription Factor)IBA 01/2021 - 03/2003
10	Peptides (Polypeptides)IBA 04/2024 - 09/2003
10	Daptomycin FDA Link 06/2023 - 07/2011
10	Peptide Hydrolases (Proteases)FDA Link 09/2022 - 02/2004
8	Hemolysin Proteins (Hemolysins)IBA 01/2019 - 06/2002
7	VaccinesIBA 04/2024 - 03/2010
7	Interleukin-8 (Interleukin 8)IBA 09/2022 - 09/2003
7	Vancomycin FDA LinkGeneric 09/2021 - 05/2010
6	ProteomeIBA 02/2024 - 10/2019
6	Colistin (Coly-Mycin)FDA Link 01/2024 - 07/2015
6	Ceftaroline FDA Link 06/2023 - 08/2013
6	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 11/2009
6	Interleukin-10 (Interleukin 10)IBA 10/2020 - 01/2012
6	Sialic Acid Binding Immunoglobulin-like LectinsIBA 06/2020 - 09/2011
6	Oxygen (Dioxygen)IBA 04/2015 - 12/2007
5	Complement System Proteins (Complement)IBA 04/2024 - 11/2014
5	AntigensIBA 02/2024 - 01/2019
5	Interleukin-6 (Interleukin 6)IBA 02/2024 - 09/2003
5	LactamsIBA 06/2023 - 07/2011
5	Methicillin (Metin)FDA Link 05/2022 - 01/2013
5	InflammasomesIBA 11/2021 - 01/2015
5	ChemokinesIBA 12/2020 - 02/2004
5	Therapeutic UsesIBA 03/2020 - 02/2004
5	PerforinIBA 01/2019 - 09/2003
5	Antimicrobial Cationic PeptidesIBA 11/2015 - 11/2006
5	IronIBA 01/2013 - 05/2006
4	beta-LactamsIBA 11/2023 - 07/2011
4	Neuraminidase (Sialidase)IBA 01/2021 - 06/2008
4	Deoxyribonucleases (DNase)FDA Link 10/2020 - 02/2006
4	LipopolysaccharidesIBA 01/2019 - 06/2007
4	Ampicillin (Omnipen)FDA LinkGeneric 01/2019 - 02/2012
4	Phosphotransferases (Kinase)IBA 01/2018 - 06/2008
4	Pattern Recognition ReceptorsIBA 01/2018 - 02/2006
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2015 - 11/2002
4	PlasminogenIBA 01/2014 - 08/2006
3	Bacterial ToxinsIBA 04/2024 - 01/2018
3	CarbohydratesIBA 04/2024 - 01/2018
3	Immunoglobulin G (IgG)IBA 12/2023 - 07/2013
3	Nafcillin FDA LinkGeneric 06/2023 - 02/2014
3	Polysaccharides (Glycans)IBA 01/2023 - 02/2007
3	AntibodiesIBA 01/2023 - 08/2010
3	Ertapenem (Invanz)FDA Link 05/2022 - 11/2016
3	Cefazolin (Ancef)FDA LinkGeneric 05/2022 - 11/2016
3	Streptococcus pneumoniae plY proteinIBA 01/2021 - 02/2011
3	Adenosine Monophosphate (AMP)IBA 03/2018 - 01/2006
3	AKB-4924IBA 01/2018 - 08/2013
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 08/2003
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 11/2010
3	LigandsIBA 01/2017 - 06/2008
3	ElementsIBA 01/2015 - 10/2005
3	Glycoproteins (Glycoprotein)IBA 12/2013 - 06/2008
3	NF-kappa B (NF-kB)IBA 09/2009 - 04/2005
3	HepcidinsIBA 07/2007 - 03/2005
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2007 - 08/2003
3	streptolysin SIBA 06/2007 - 01/2002
3	DefensinsIBA 11/2006 - 09/2003
3	streptococcal group B hemolysinIBA 04/2005 - 06/2002
2	C5a peptidaseIBA 12/2023 - 01/2019

Therapy/Procedure

48	Therapeutics 05/2024 - 10/2005