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Mark R Nicolls Selected Research

Hypertrophy

6/2015Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling.
8/2013Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.

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Mark R Nicolls Research Topics

Disease

21Inflammation (Inflammations)
11/2023 - 05/2005
16Hypoxia (Hypoxemia)
01/2023 - 06/2007
16Pulmonary Arterial Hypertension
01/2023 - 11/2012
9Pulmonary Hypertension
03/2023 - 10/2012
8Infections
04/2022 - 10/2004
6Pneumonia (Pneumonitis)
01/2021 - 07/2006
6Ischemia
01/2019 - 07/2010
5Systemic Scleroderma (Systemic Sclerosis)
03/2024 - 12/2010
5Lymphedema (Milroy Disease)
04/2021 - 10/2017
5Bronchiolitis Obliterans Syndrome
01/2021 - 05/2005
5Lung Diseases (Lung Disease)
01/2020 - 03/2007
4Vascular Remodeling
01/2023 - 05/2014
4COVID-19
01/2023 - 08/2021
4Neoplasms (Cancer)
04/2022 - 09/2003
4Emphysema
10/2020 - 04/2005
4Connective Tissue Diseases (Connective Tissue Disease)
12/2014 - 12/2010
4Fibrosis (Cirrhosis)
06/2011 - 04/2005
3Inborn Genetic Diseases (Disease, Hereditary)
04/2022 - 08/2021
3Cystic Fibrosis (Mucoviscidosis)
04/2022 - 08/2021
3Vascular System Injuries
01/2021 - 01/2016
3Insulin Resistance
01/2021 - 02/2004
3Vascular Diseases (Vascular Disease)
08/2016 - 07/2007
3Asthma (Bronchial Asthma)
04/2014 - 07/2006
3Airway Remodeling
04/2013 - 04/2005
3Eosinophilia
07/2006 - 07/2006
2Chronic Obstructive Pulmonary Disease (COPD)
03/2023 - 11/2006
2Disease Progression
10/2021 - 07/2005
2Bronchiolitis
01/2021 - 06/2011
2Hyperplasia
01/2020 - 07/2006
2Hypertrophy
06/2015 - 08/2013
2Rheumatoid Arthritis
04/2013 - 12/2010
2Respiratory Insufficiency (Respiratory Failure)
08/2012 - 09/2011
2Lung Injury
08/2012 - 09/2011
2Type 2 Diabetes Mellitus (MODY)
07/2005 - 03/2003
2Amyloid Plaque
02/2004 - 03/2003
2Alzheimer Disease (Alzheimer's Disease)
02/2004 - 03/2003
1Airway Obstruction (Choking)
03/2023
1Muscle Tissue Neoplasms
01/2023
1Necrosis
04/2022
1Right Ventricular Dysfunction
10/2021

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
01/2023 - 03/2003
7Leukotriene B4IBA
01/2023 - 08/2013
7Semaxinib (SU5416)IBA
01/2021 - 10/2012
6CytokinesIBA
10/2021 - 07/2006
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 11/2006
4Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
02/2023 - 09/2011
4ElafinIBA
10/2022 - 08/2012
4LeukotrienesIBA
01/2020 - 07/2006
4Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2015 - 11/2006
4thymoquinoneIBA
04/2007 - 07/2006
3Pancreatic Elastase (Elastase)IBA
10/2022 - 08/2012
3Deoxyribonucleases (DNase)FDA Link
04/2022 - 08/2021
3Hyaluronoglucosaminidase (Hyaluronidase)FDA Link
04/2022 - 08/2021
3Hyaluronic Acid (Hyaluronan)IBA
04/2022 - 08/2021
3DNA (Deoxyribonucleic Acid)IBA
04/2022 - 08/2021
3ChemokinesIBA
01/2020 - 05/2005
3AutoantibodiesIBA
01/2018 - 04/2013
3AntigensIBA
11/2017 - 07/2006
3Biomarkers (Surrogate Marker)IBA
06/2014 - 08/2011
3Complement System Proteins (Complement)IBA
04/2014 - 11/2011
3OvalbuminIBA
11/2012 - 07/2006
3AntibodiesIBA
12/2010 - 04/2005
2Rituximab (Mabthera)FDA Link
03/2024 - 01/2021
2Immunoglobulins (Immunoglobulin)IBA
01/2024 - 10/2004
2Carbon MonoxideIBA
03/2023 - 12/2010
2Leukocyte Elastase (Neutrophil Elastase)IBA
10/2022 - 10/2021
2Brain Natriuretic Peptide (Natrecor)FDA Link
10/2021 - 12/2010
2Clopidogrel (Plavix)FDA Link
01/2021 - 01/2019
2Cell-Free Nucleic AcidsIBA
01/2021 - 10/2015
2Transcription Factors (Transcription Factor)IBA
10/2020 - 06/2007
2MonocrotalineIBA
10/2019 - 08/2013
2Masoprocol (Actinex)FDA Link
01/2019 - 01/2018
2Ketoprofen (Orudis)FDA LinkGeneric
10/2018 - 10/2017
2Interleukin-6 (Interleukin 6)IBA
11/2017 - 11/2012
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
10/2017 - 07/2006
2Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
10/2017 - 05/2014
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2015 - 07/2005
27-(N-(3-aminopropyl)amino)heptan-2-oneIBA
12/2014 - 12/2010
2Arachidonic Acid (Vitamin F)IBA
05/2014 - 07/2006
2ElastinIBA
08/2012 - 09/2011
2Volatile Oils (Essential Oils)IBA
07/2006 - 07/2006
2AllergensIBA
07/2006 - 07/2006
1MucinsIBA
01/2024
1hydralazine 4-anisaldehyde hydrazoneIBA
11/2023
1Toll-Like Receptor 3IBA
02/2023
1acebilustatIBA
01/2023
1Antiviral Agents (Antivirals)IBA
01/2023
16-pyruvoyltetrahydropterin synthase (PTPS)IBA
01/2023
1Protein Tyrosine PhosphatasesIBA
01/2023
1Small Interfering RNA (siRNA)IBA
01/2023
1Circular RNAIBA
12/2022
1Versicans (Versican)IBA
04/2022
1ubenimexIBA
04/2021

Therapy/Procedure

12Lung Transplantation
01/2021 - 10/2004
7Therapeutics
03/2024 - 05/2005
5Transplantation
02/2019 - 04/2005
4Immunotherapy
01/2020 - 04/2005
3Artificial Respiration (Mechanical Ventilation)
04/2014 - 09/2011
3Intraperitoneal Injections
11/2006 - 07/2006
1Precision Medicine
03/2024