Gunnar Naulaers Selected Research

Induced Hypothermia

1/2024	Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome - a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).
1/2019	Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).
1/2019	Outcome of Infants with Therapeutic Hypothermia after Perinatal Asphyxia and Early-Onset Sepsis.
1/2018	Measuring Near-Infrared Spectroscopy Derived Cerebral Autoregulation in Neonates: From Research Tool Toward Bedside Multimodal Monitoring.
1/2013	Introduction of hypothermia for neonates with perinatal asphyxia in the Netherlands and Flanders.

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Gunnar Naulaers Research Topics

Disease

5	Brain Injuries (Brain Injury) 03/2024 - 01/2019
5	Asphyxia (Suffocation) 01/2022 - 01/2013
4	Hypothermia 03/2024 - 01/2019
3	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2024 - 01/2018
3	Pain (Aches) 01/2021 - 06/2003
3	Hypoxia (Hypoxemia) 01/2021 - 11/2018
3	Hypotension (Low Blood Pressure) 01/2021 - 01/2018
3	Birth Weight (Birth Weights) 12/2014 - 03/2009
3	Retinopathy of Prematurity (Retrolental Fibroplasia) 05/2012 - 03/2003
2	Premature Birth (Birth, Premature) 01/2023 - 08/2019
2	Hemorrhage 01/2021 - 12/2002
1	Brain Ischemia (Cerebral Ischemia) 01/2024
1	Brain Hypoxia (Cerebral Hypoxia) 01/2021
1	Heart Arrest (Cardiac Arrest) 08/2020
1	Pregnancy Complications 08/2019
1	Teratoma (Teratoid Tumor) 06/2019
1	Tracheomalacia 01/2019
1	Brain Diseases (Brain Disorder) 01/2019
1	Esophageal Stenosis (Esophageal Stricture) 01/2019
1	Gastroesophageal Reflux (GERD) 01/2019
1	Disease Progression 01/2019
1	Sepsis (Septicemia) 01/2019
1	Congenital Heart Defects (Congenital Heart Defect) 01/2018
1	Hyperoxia 01/2016
1	Inflammation (Inflammations) 01/2016
1	Apnea 01/2016
1	Neonatal Sepsis 12/2014
1	Weight Gain 09/2013
1	Body Weight (Weight, Body) 06/2013
1	Wounds and Injuries (Trauma) 01/2013
1	Hyperbilirubinemia 01/2012
1	Epidermolysis Bullosa 10/2010
1	Procedural Pain 09/2010
1	Fetofetal Transfusion (Twin Transfusion Syndrome) 02/2010
1	Bronchopulmonary Dysplasia 01/2010
1	Hyperglycemia 07/2009
1	Failure to Thrive 03/2003
1	Periventricular Leukomalacia (Neonatal Cerebral Leukomalacia) 12/2002
1	Atrophy 12/2002
1	Hydrocephalus (Hydrocephaly) 12/2002

Drug/Important Bio-Agent (IBA)

3	Allopurinol (Remid)FDA LinkGeneric 03/2024 - 01/2019
3	Analgesics (Analgesic Drugs)IBA 01/2021 - 06/2003
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2013 - 09/2010
2	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2022
2	Dopamine (Intropin)FDA LinkGeneric 01/2021 - 01/2018
2	Oxygen (Dioxygen)IBA 01/2021 - 09/2013
2	Thyroid HormonesIBA 11/2020 - 08/2019
2	Propofol (Diprivan)FDA LinkGeneric 11/2018 - 06/2013
1	Xanthine OxidaseIBA 01/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024
1	Midazolam (Versed)FDA LinkGeneric 01/2021
1	Sevoflurane (Ultane)FDA LinkGeneric 01/2021
1	Hypnotics and Sedatives (Sedatives)IBA 01/2021
1	Proteins (Proteins, Gene)FDA Link 08/2019
1	Neuroprotective AgentsIBA 01/2019
1	Caffeine (No Doz)FDA LinkGeneric 01/2016
1	Vancomycin FDA LinkGeneric 12/2014
1	Indicators and Reagents (Reagents)IBA 09/2013
1	Retinaldehyde (Retinal)IBA 09/2013
1	Alprostadil (Muse)FDA LinkGeneric 01/2013
1	Glucose (Dextrose)FDA LinkGeneric 05/2012
1	SodiumIBA 01/2012
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2012
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2012
1	EnzymesIBA 01/2012
1	Gabapentin (Neurontin)FDA LinkGeneric 10/2010
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2010
1	Brimonidine Tartrate (Alphagan)FDA LinkGeneric 07/2009

Therapy/Procedure

5	Induced Hypothermia 01/2024 - 01/2013
2	Neonatal Intensive Care 01/2024 - 08/2013
2	Critical Care (Surgical Intensive Care) 01/2023 - 03/2009
2	Cryotherapy (Therapy, Cold) 06/2003 - 03/2003
1	Skin Care 01/2023
1	Anesthesia 01/2021
1	Terminal Care (Care, Terminal) 01/2021
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 08/2020
1	Neurosurgical Procedures 08/2020
1	Tracheostomy 06/2019
1	Enteral Nutrition (Feeding, Tube) 01/2019
1	Analgesia 10/2010
1	Laser Therapy (Surgery, Laser) 02/2010
1	Therapeutics 02/2010
1	Enterostomy 03/2003
1	Aftercare (After-Treatment) 12/2002