Michael P Murphy Selected Research

Pain (Aches)

1/2018	Rationale and design of the Clinical and Histologic Analysis of Mesenchymal Stromal Cells in AmPutations (CHAMP) trial investigating the therapeutic mechanism of mesenchymal stromal cells in the treatment of critical limb ischemia.
1/2017	Rationale and design of the MarrowStim PAD Kit for the Treatment of Critical Limb Ischemia in Subjects with Severe Peripheral Arterial Disease (MOBILE) trial investigating autologous bone marrow cell therapy for critical limb ischemia.
1/2016	Autologous bone marrow mononuclear cell therapy for critical limb ischemia is effective and durable.

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Michael P Murphy Research Topics

Disease

33	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 05/2006
31	Ischemia 03/2024 - 07/2005
28	Inflammation (Inflammations) 04/2024 - 01/2010
28	Hypoxia (Hypoxemia) 03/2024 - 12/2003
26	Reperfusion Injury 04/2024 - 07/2005
21	Neoplasms (Cancer) 04/2024 - 03/2009
11	Alzheimer Disease (Alzheimer's Disease) 12/2020 - 01/2006
10	Myocardial Infarction 04/2024 - 06/2013
9	Necrosis 12/2023 - 07/2005
8	Stroke (Strokes) 04/2024 - 08/2009
8	Obesity 01/2020 - 06/2006
8	Chronic Limb-Threatening Ischemia 01/2018 - 08/2008
7	Heart Failure 04/2024 - 04/2010
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 08/2009
7	Abdominal Aortic Aneurysm 12/2018 - 09/2012
6	Infections 12/2023 - 08/2010
6	Infarction (Infarctions) 01/2023 - 03/2013
6	Breast Neoplasms (Breast Cancer) 03/2022 - 09/2010
6	Fibrosis (Cirrhosis) 04/2021 - 10/2012
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2009
6	Atherosclerosis 12/2017 - 05/2009
6	Parkinson Disease (Parkinson's Disease) 01/2013 - 11/2004
5	Body Weight (Weight, Body) 04/2024 - 01/2012
5	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022 - 06/2014
5	Disease Progression 10/2018 - 10/2003
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2016 - 10/2010
4	Brain Injuries (Brain Injury) 01/2023 - 06/2006
4	Sepsis (Septicemia) 01/2021 - 04/2006
4	Hyperglycemia 11/2020 - 02/2004
4	Insulin Resistance 01/2020 - 01/2012
4	Type 2 Diabetes Mellitus (MODY) 01/2019 - 01/2011
4	Peripheral Arterial Disease 04/2017 - 08/2008
4	Fatty Liver 10/2015 - 08/2010
4	Hypertension (High Blood Pressure) 03/2014 - 05/2007
3	Aortic Aneurysm (Aneurysm, Aortic) 12/2023 - 03/2009
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2022 - 11/2016
3	Neoplasm Metastasis (Metastasis) 10/2022 - 03/2022
3	Wounds and Injuries (Trauma) 01/2022 - 11/2013
3	Cardiomyopathies (Cardiomyopathy) 01/2021 - 12/2019
3	Acute Kidney Injury (Acute Renal Failure) 10/2020 - 08/2015
3	Thrombosis (Thrombus) 10/2020 - 01/2018
3	Memory Disorders (Memory Loss) 01/2020 - 04/2011
3	Pathologic Constriction (Stenosis) 01/2019 - 01/2018
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 03/2016
3	Pain (Aches) 01/2018 - 01/2016
3	Atherosclerotic Plaque (Atheroma) 12/2017 - 03/2012
3	Glucose Intolerance 04/2016 - 10/2010

Drug/Important Bio-Agent (IBA)

53	AntioxidantsIBA 02/2024 - 10/2003
45	mitoquinoneIBA 02/2024 - 07/2005
44	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2024 - 02/2004
23	Superoxides (Superoxide)IBA 04/2024 - 04/2006
23	Succinic Acid (Succinate)IBA 03/2024 - 11/2014
19	Proteins (Proteins, Gene)FDA Link 12/2023 - 04/2005
15	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 02/2004
13	Oxygen (Dioxygen)IBA 03/2024 - 12/2003
13	Mitochondrial DNA (mtDNA)IBA 10/2020 - 12/2006
11	Adenosine Triphosphate (ATP)IBA 03/2024 - 06/2006
11	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022 - 04/2005
8	CytokinesIBA 04/2023 - 08/2013
8	Mitochondrial Proteins (Mitochondrial Protein)IBA 12/2018 - 10/2003
7	Biomarkers (Surrogate Marker)IBA 02/2021 - 12/2008
6	LipidsIBA 01/2023 - 09/2007
6	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 10/2010
5	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2023 - 11/2014
4	malonic acid (malonate)IBA 01/2023 - 01/2020
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 07/2005
4	Anti-Bacterial Agents (Antibiotics)IBA 11/2021 - 04/2009
4	Amyloid beta-PeptidesIBA 12/2020 - 01/2006
4	EnzymesIBA 01/2020 - 05/2006
4	Oxidants (Oxidizing Agents)IBA 01/2020 - 08/2008
4	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 06/2006
4	Amyloid (Amyloid Fibrils)IBA 01/2018 - 01/2006
4	Apolipoproteins E (ApoE)IBA 12/2017 - 10/2010
4	S-NitrosothiolsIBA 01/2017 - 06/2009
3	Angiotensin IIIBA 02/2024 - 03/2014
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2024 - 12/2003
3	Adenosine Diphosphate (ADP)IBA 01/2023 - 01/2019
3	ProdrugsIBA 01/2022 - 08/2008
3	Cysteine (L-Cysteine)FDA Link 01/2022 - 06/2013
3	Pyruvic Acid (Pyruvate)IBA 01/2022 - 07/2017
3	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 08/2015
3	Pyruvaldehyde (Methylglyoxal)IBA 04/2021 - 02/2014
3	Transcription Factors (Transcription Factor)IBA 01/2019 - 09/2012
3	Drinking WaterIBA 12/2018 - 08/2009
3	NAD (NADH)IBA 01/2018 - 10/2014
3	ApolipoproteinsIBA 01/2018 - 10/2010
3	Sulfhydryl Compounds (Thiols)IBA 01/2017 - 06/2009
3	triphenylphosphoniumIBA 10/2016 - 06/2013
3	Superoxide DismutaseIBA 03/2015 - 05/2006
3	InflammasomesIBA 02/2014 - 05/2012
3	3-nitrotyrosineIBA 08/2013 - 07/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2024 - 11/2020
2	methyl malonateIBA 03/2023 - 01/2020

Therapy/Procedure

38	Therapeutics 02/2024 - 11/2005
7	Cell- and Tissue-Based Therapy (Cell Therapy) 11/2020 - 04/2009
7	Surgical Amputation (Amputations) 01/2018 - 08/2008
5	Stents 10/2020 - 01/2018
5	Endovascular Aneurysm Repair 05/2019 - 10/2012
4	Ligation 01/2022 - 08/2008
4	Transplantation 01/2018 - 04/2010