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Masatomo Miura Selected Research

BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)

1/2022Relationship between achievement of major molecular response or deep molecular response and nilotinib plasma concentration in patients with chronic myeloid leukemia receiving first-line nilotinib therapy.
11/2021Regulatory T Cell as a Biomarker of Treatment-Free Remission in Patients with Chronic Myeloid Leukemia.
10/2021Serial evaluation of the pharmacokinetics of ponatinib in patients with CML and Ph + ALL.
1/2021The BCRP inhibitor febuxostat enhances the effect of nilotinib by regulation of intracellular concentration.
1/2021Effects of SLC22A2 808G>T polymorphism and bosutinib concentrations on serum creatinine in patients with chronic myeloid leukemia receiving bosutinib therapy.
11/2020The Impact of Hemodialysis and Liver Cirrhosis on the Plasma Concentrations of Tyrosine Kinase Inhibitors in a Patient with Chronic Myeloid Leukemia.
7/2020Pharmacokinetics of dasatinib in a hemodialysis patient with chronic myeloid leukemia and chronic kidney disease.
1/2019[Management using the plasma concentration of tyrosine kinase inhibitors for the treatment of chronic myelogenous leukemia: an update].
8/2018Switching to nilotinib is associated with deeper molecular responses in chronic myeloid leukemia chronic phase with major molecular responses to imatinib: STAT1 trial in Japan.
5/2018Effects of polymorphisms in NR1I2, CYP3A4, and ABC transporters on the steady-state plasma trough concentrations of bosutinib in Japanese patient with chronic myeloid leukemia.
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Masatomo Miura Research Topics

Disease

20BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2022 - 11/2010
12Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2023 - 02/2014
10Neoplasms (Cancer)
01/2023 - 10/2009
8Body Weight (Weight, Body)
11/2017 - 10/2007
7Diarrhea
12/2022 - 10/2007
6Philadelphia Chromosome
01/2023 - 01/2011
6Breast Neoplasms (Breast Cancer)
01/2021 - 10/2008
5Esophageal Neoplasms (Esophageal Cancer)
01/2022 - 10/2009
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2021 - 05/2012
5Multiple Myeloma
05/2019 - 08/2014
4Renal Cell Carcinoma (Grawitz Tumor)
12/2024 - 01/2017
3Hand-Foot Syndrome
12/2024 - 01/2019
3Proteinuria
12/2024 - 01/2019
3Esophageal Squamous Cell Carcinoma
12/2022 - 01/2012
3Exanthema (Rash)
12/2022 - 07/2015
3Lymphatic Metastasis
12/2022 - 06/2013
3Neoplasm Metastasis (Metastasis)
12/2022 - 06/2013
3Thyroid Neoplasms (Thyroid Cancer)
05/2022 - 01/2019
3Infections
11/2019 - 11/2007
3Fibrosis (Cirrhosis)
05/2018 - 01/2011
3Squamous Cell Neoplasms (Squamous Cell Cancer)
03/2013 - 07/2011
2Pathologic Constriction (Stenosis)
06/2023 - 01/2018
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2022 - 01/2022
2Schizophrenia (Dementia Praecox)
10/2021 - 11/2017
2Leukemia
08/2021 - 04/2012
2Stroke (Strokes)
01/2021 - 12/2017
2Hyperlipidemias (Hyperlipidemia)
06/2020 - 10/2007
2Colorectal Neoplasms (Colorectal Cancer)
04/2020 - 12/2014
2Ischemic Stroke
11/2019 - 12/2010
2Hypertension (High Blood Pressure)
03/2019 - 01/2019
2Pleural Effusion (Pleural Effusions)
01/2019 - 01/2015
2Chronic Kidney Failure (Chronic Renal Failure)
10/2017 - 04/2012
2Acute Kidney Injury (Acute Renal Failure)
07/2016 - 08/2008
2Hyperbilirubinemia
03/2014 - 01/2014
1Prostatic Neoplasms (Prostate Cancer)
01/2023

Drug/Important Bio-Agent (IBA)

13Tacrolimus (Prograf)FDA LinkGeneric
11/2019 - 11/2007
12Cytochrome P-450 CYP3AIBA
12/2022 - 08/2008
10nilotinibFDA Link
01/2022 - 04/2012
9Tyrosine Kinase InhibitorsIBA
12/2024 - 09/2013
8Imatinib Mesylate (Gleevec)FDA Link
01/2019 - 11/2010
7Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2007
7Dasatinib (BMS 354825)FDA Link
07/2020 - 04/2012
7C-Reactive ProteinIBA
01/2015 - 10/2009
6Gefitinib (Iressa)FDA Link
08/2020 - 02/2014
5ATP-Binding Cassette Transporters (ABC Transporters)IBA
10/2023 - 11/2017
5Lenalidomide (CC 5013)FDA Link
05/2019 - 08/2014
5Peptides (Polypeptides)IBA
12/2014 - 12/2007
4Interleukin-6 (Interleukin 6)IBA
01/2023 - 10/2009
4bosutinibIBA
01/2021 - 01/2018
4DNA (Deoxyribonucleic Acid)IBA
06/2014 - 10/2010
4AnionsIBA
11/2010 - 12/2007
3osimertinibIBA
09/2023 - 10/2017
3ponatinibIBA
01/2023 - 01/2019
3lenvatinibIBA
05/2022 - 01/2019
3Dexamethasone (Maxidex)FDA LinkGeneric
05/2019 - 01/2018
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
09/2015 - 10/2008
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
01/2015 - 12/2007
3Uridine Diphosphate (UDP)IBA
03/2014 - 01/2009
3Interleukin-2 (IL2)IBA
07/2011 - 10/2009
3Interleukin-10 (Interleukin 10)IBA
07/2011 - 10/2009
3Interleukin-4 (Interleukin 4)IBA
07/2011 - 10/2009
3CytokinesIBA
07/2011 - 11/2007
3ATP-Binding Cassette Sub-Family B Member 4IBA
11/2010 - 10/2008
2Axitinib (AG 013736)IBA
12/2024 - 03/2018
2AfatinibIBA
10/2023 - 10/2021
2Pregnane X ReceptorIBA
10/2023 - 05/2018
2Indicators and Reagents (Reagents)IBA
12/2022 - 06/2014
2venetoclaxIBA
10/2022 - 01/2022
2Clarithromycin (Biaxin)FDA LinkGeneric
01/2022 - 06/2018
2PlatinumIBA
01/2022 - 01/2021
2Clozapine (Clozaril)FDA LinkGeneric
10/2021 - 11/2017
2Immunosuppressive Agents (Immunosuppressants)IBA
11/2019 - 07/2012
2Sunitinib (Sutent)FDA Link
05/2018 - 01/2017
2Proton Pump InhibitorsIBA
11/2017 - 04/2012
2Cytochrome P-450 CYP2D6 (CYP2D6)IBA
11/2017 - 07/2015
2EnzymesIBA
07/2015 - 07/2011
2Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
03/2014 - 01/2014
2Lansoprazole (Prevacid)FDA LinkGeneric
04/2012 - 09/2010
2Triglycerides (Triacylglycerol)IBA
01/2011 - 10/2007
2InterleukinsIBA
05/2010 - 10/2009
2Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
05/2010 - 10/2009
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 10/2009
2Interferon-gamma (Interferon, gamma)IBA
11/2009 - 10/2009
1Abiraterone AcetateIBA
01/2023
1abirateroneIBA
01/2023
1Cytokine Receptor gp130IBA
01/2023
1Immune Checkpoint InhibitorsIBA
01/2023
1AngiopoietinsIBA
05/2022
1Azacitidine (5 Azacytidine)FDA Link
01/2022

Therapy/Procedure

17Therapeutics
12/2022 - 09/2010
8Transplantation
11/2019 - 08/2008
6Kidney Transplantation
11/2019 - 08/2008
5Esophagectomy
12/2022 - 10/2009
5Renal Dialysis (Hemodialysis)
11/2020 - 04/2012
5Drug Therapy (Chemotherapy)
04/2020 - 07/2012
2Thrombectomy
06/2023 - 01/2021
2Stents
01/2020 - 11/2018
2Cranial Irradiation
12/2017 - 01/2015
2Lymph Node Excision (Lymph Node Dissection)
06/2014 - 06/2013
1Chemoradiotherapy
12/2022