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Gordon Mills Selected Research

Melanoma (Melanoma, Malignant)

10/2023Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
11/2021TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors.
12/2018Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis.
1/2018Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.
10/2017PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas.
1/2013Perturbation biology: inferring signaling networks in cellular systems.

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Gordon Mills Research Topics

Disease

19Neoplasms (Cancer)
10/2023 - 01/2005
6Melanoma (Melanoma, Malignant)
10/2023 - 01/2013
4Breast Neoplasms (Breast Cancer)
01/2020 - 11/2006
3Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 01/2007
3Neoplasm Metastasis (Metastasis)
01/2015 - 01/2014
2Glioma (Gliomas)
12/2021 - 06/2015
2Hypoxia (Hypoxemia)
01/2012 - 12/2008
2Lung Neoplasms (Lung Cancer)
08/2010 - 05/2008
1Colorectal Neoplasms (Colorectal Cancer)
12/2022
1Myocardial Infarction
12/2021
1ST Elevation Myocardial Infarction
12/2021
1COVID-19
12/2021
1Nevus (Nevi)
12/2018
1Carcinoma (Carcinomatosis)
05/2009
1Squamous Cell Carcinoma of Head and Neck
03/2009
1Head and Neck Neoplasms (Head and Neck Cancer)
03/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2008
1Parkinson Disease (Parkinson's Disease)
12/2008
1Glioblastoma (Glioblastoma Multiforme)
05/2008
1Ovarian Epithelial Carcinoma
03/2008
1Ascites
01/2007
1Carcinogenesis
11/2006

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
01/2023 - 03/2009
4DNA (Deoxyribonucleic Acid)IBA
11/2021 - 01/2015
3RNA (Ribonucleic Acid)IBA
10/2023 - 06/2015
3Biomarkers (Surrogate Marker)IBA
12/2022 - 01/2007
2Messenger RNA (mRNA)IBA
01/2023 - 06/2015
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2021 - 10/2017
2Glucose (Dextrose)FDA LinkGeneric
01/2015 - 01/2015
2Mitochondrial DNA (mtDNA)IBA
01/2015 - 01/2015
2lysophosphatidic acidIBA
01/2012 - 01/2007
2ErbB Receptors (EGF Receptor)IBA
08/2010 - 03/2009
1Lipid NanoparticlesIBA
10/2023
1Programmed Cell Death 1 ReceptorIBA
10/2023
1RNA-Binding Proteins (RNA-Binding Protein)IBA
12/2022
1Tumor Biomarkers (Tumor Markers)IBA
12/2022
1Lipid Bilayers (Lipid Bilayer)IBA
12/2022
1PlatinumIBA
01/2022
1Ribose (D-Ribose)IBA
01/2022
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2022
1omega-Chloroacetophenone (Mace)IBA
12/2021
1alpha-2'-deoxythioguanosineIBA
12/2021
1Temozolomide (Temodar)FDA LinkGeneric
12/2021
1NucleosidesIBA
12/2021
1IronIBA
01/2020
1Glutathione (Reduced Glutathione)IBA
01/2020
1MicroRNAs (MicroRNA)IBA
06/2015
1ChromatinIBA
01/2014
1raf KinasesIBA
01/2013
1alkylglycerophosphoethanolamine phosphodiesteraseIBA
01/2012
1Lysophosphatidic Acid ReceptorsIBA
01/2012
1Small Interfering RNA (siRNA)IBA
08/2010
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
08/2010
1Tyrosine Kinase InhibitorsIBA
08/2010
1Steroid Receptors (Steroid Receptor)IBA
08/2010
1Gefitinib (Iressa)FDA Link
08/2010
1Histone Acetyltransferases (Histone Acetyltransferase)IBA
08/2010
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
05/2009
1TensinsIBA
05/2009
1Antisense DNAIBA
03/2009
1deguelinIBA
12/2008
1Protein Isoforms (Isoforms)IBA
05/2008
1Complementary DNA (cDNA)IBA
05/2008
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
05/2008
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
05/2008
1Oral ContraceptivesIBA
03/2008
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
01/2007
1lysophosphatidylserineIBA
01/2007
1lysophosphatidylinositolIBA
01/2007
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2007
1sphingosine phosphorylcholineIBA
01/2007
1LysophospholipidsIBA
01/2007
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2007
1EnzymesIBA
01/2007
1Conditioned Culture MediaIBA
01/2007
1Estrogen Receptor alphaIBA
11/2006
1I-kappa B KinaseIBA
11/2006

Therapy/Procedure

8Therapeutics
11/2021 - 01/2007
2Chemoprevention
12/2008 - 01/2005
1Immunotherapy
10/2023
1Percutaneous Coronary Intervention
12/2021
1Drug Therapy (Chemotherapy)
03/2008