Pietro Mesirca Selected Research

Heart Block

1/2020	Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.
2/2016	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.

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Pietro Mesirca Research Topics

Disease

3	Bradycardia 02/2024 - 01/2020
2	Sick Sinus Syndrome 01/2020 - 02/2016
2	Heart Block 01/2020 - 02/2016
1	Sepsis (Septicemia) 11/2023
1	Infarction (Infarctions) 01/2023
1	Inflammation (Inflammations) 11/2021
1	Heart Failure 07/2013
1	Atrial Fibrillation 07/2013
1	Cardiomegaly (Heart Hypertrophy) 07/2013
1	Polymorphic catecholergic ventricular tachycardia 07/2012

Drug/Important Bio-Agent (IBA)

4	GTP-Binding Proteins (G-Protein)IBA 01/2023 - 02/2016
2	MicroRNAs (MicroRNA)IBA 11/2021 - 01/2020
1	LipopolysaccharidesIBA 11/2023
1	Ion Channels (Ion Channel)IBA 11/2023
1	CytokinesIBA 11/2023
1	Muscarinic AgonistsIBA 11/2023
1	ChloridesIBA 01/2023
1	L-Type Calcium Channels (Dihydropyridine Receptor)IBA 01/2023
1	G Protein-Coupled Inwardly-Rectifying Potassium ChannelsIBA 01/2023
1	IvabradineIBA 01/2023
1	Transcription Factors (Transcription Factor)IBA 11/2021
1	tertiapinIBA 01/2020
1	Inwardly Rectifying Potassium Channels (Inward Rectifier Potassium Channels)IBA 01/2020
1	Hyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIBA 01/2020
1	Cholinergic Agents (Cholinergics)IBA 02/2016
1	TRPC6 Cation ChannelIBA 07/2013
1	Trinitrotoluene (TNT)IBA 07/2013
1	Phosphotransferases (Kinase)IBA 07/2013
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 07/2012
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 07/2012

Therapy/Procedure

2	Therapeutics 02/2024 - 01/2020