Jorge Melendez-Zajgla Selected Research

Small Interfering RNA (siRNA)

11/2016	NF-kappaΒ-inducing kinase regulates stem cell phenotype in breast cancer.
12/2014	Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

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Jorge Melendez-Zajgla Research Topics

Disease

38	Neoplasms (Cancer) 03/2024 - 02/2002
19	Breast Neoplasms (Breast Cancer) 05/2023 - 10/2010
7	Uterine Cervical Neoplasms (Cancer of the Cervix) 02/2022 - 01/2005
5	Neoplasm Metastasis (Metastasis) 05/2023 - 01/2005
4	Carcinogenesis 09/2018 - 01/2015
3	Adenocarcinoma 01/2021 - 02/2006
3	Hypoxia (Hypoxemia) 11/2020 - 10/2010
2	Pathologic Processes 04/2021 - 01/2017
2	Triple Negative Breast Neoplasms 12/2019 - 06/2012
1	Vomiting 12/2022
1	Nausea 12/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 09/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Immunoglobulin Light-chain Amyloidosis 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2018
1	Amyloidosis 01/2017
1	Neuroblastoma 01/2016
1	Lung Diseases (Lung Disease) 09/2015
1	Osteosarcoma (Osteogenic Sarcoma) 12/2014
1	Insulin Resistance 10/2014
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2014
1	Aneuploidy (Aneuploid) 08/2010
1	Giant Cell Tumors (Giant Cell Tumor) 02/2002

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 05/2023 - 02/2006
7	Messenger RNA (mRNA)IBA 01/2021 - 02/2006
6	MicroRNAs (MicroRNA)IBA 05/2023 - 01/2016
5	RNA (Ribonucleic Acid)IBA 02/2022 - 12/2014
5	Long Noncoding RNAIBA 11/2020 - 01/2018
4	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 02/2012
3	LigandsIBA 05/2023 - 04/2021
3	Estrogen ReceptorsIBA 12/2022 - 02/2002
3	Untranslated RNA (Noncoding RNA)IBA 01/2021 - 10/2017
3	NF-kappaB-Inducing KinaseIBA 01/2019 - 11/2016
3	Metalloproteases (Metalloproteinases)IBA 10/2018 - 01/2005
3	DNA (Deoxyribonucleic Acid)IBA 10/2015 - 08/2011
2	Biomarkers (Surrogate Marker)IBA 09/2022 - 01/2018
2	CytokinesIBA 11/2020 - 10/2014
2	NF-kappa B (NF-kB)IBA 01/2020 - 11/2016
2	Phosphotransferases (Kinase)IBA 01/2019 - 11/2016
2	Protein Isoforms (Isoforms)IBA 01/2017 - 02/2006
2	SurvivinIBA 01/2017 - 02/2006
2	Tissue Inhibitor of Metalloproteinase-4IBA 12/2016 - 01/2015
2	Small Interfering RNA (siRNA)IBA 11/2016 - 12/2014
2	Probenecid (Benemid)FDA LinkGeneric 01/2016 - 02/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2023
1	tetraethylpyrazine (TEP)IBA 05/2023
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 12/2022
1	CorticosteroneIBA 12/2022
1	AntiemeticsIBA 12/2022
1	GlucocorticoidsIBA 12/2022
1	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2022
1	AgarIBA 09/2022
1	ChemokinesIBA 02/2022
1	Transcription Factors (Transcription Factor)IBA 06/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 04/2021
1	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 04/2021
1	Leucine (L-Leucine)FDA Link 04/2021
1	CateninsIBA 01/2021
1	Tumor Biomarkers (Tumor Markers)IBA 01/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2020
1	CholesterolIBA 01/2019
1	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2019
1	Matrix Metalloproteinase 17IBA 10/2018
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2018
1	Amyloid (Amyloid Fibrils)IBA 01/2017
1	Aldehyde DehydrogenaseIBA 11/2016
1	Oxygen (Dioxygen)IBA 03/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2016
1	TensinsIBA 01/2016
1	Particulate MatterIBA 09/2015
1	TOR Serine-Threonine KinasesIBA 12/2014
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 12/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2014
1	NucleotidesIBA 02/2014
1	HLA-B Antigens (HLA-B)IBA 02/2014
1	Progesterone Receptors (Progesterone Receptor)IBA 06/2012
1	Drug CombinationsIBA 02/2012
1	Antineoplastic Agents (Antineoplastics)IBA 02/2012
1	Paclitaxel (Taxol)FDA LinkGeneric 02/2012
1	AnionsIBA 02/2012
1	Fluconazole (Zonal)FDA LinkGeneric 10/2010
1	Estrogens (Estrogen)FDA Link 10/2010
1	Estrogen Receptor alphaIBA 10/2010
1	Hormones (Hormone)IBA 10/2010
1	Oncogene Proteins (Oncogene Protein)IBA 08/2010
1	PeptidomimeticsIBA 09/2008
1	Caspase 3 (Caspase-3)IBA 07/2006
1	ukrainIBA 07/2006
1	Caspase 9IBA 07/2006
1	Tissue Inhibitor of Metalloproteinase-1IBA 01/2005

Therapy/Procedure

7	Therapeutics 01/2023 - 09/2008
4	Drug Therapy (Chemotherapy) 12/2022 - 10/2010
1	Aftercare (After-Treatment) 01/2022
1	Radiotherapy 11/2020