Richard A Manderville Selected Research

Carcinogenesis

1/2018	Molecular Dynamics Simulations of Mismatched DNA Duplexes Associated with the Major C8-Linked 2'-Deoxyguanosine Adduct of the Food Mutagen Ochratoxin A: Influence of Opposing Base, Adduct Ionization State, and Sequence on the Structure of Damaged DNA.
2/2012	An update on direct genotoxicity as a molecular mechanism of ochratoxin a carcinogenicity.
1/2010	Structures of covalent adducts between DNA and ochratoxin a: a new factor in debate about genotoxicity and human risk assessment.
1/2007	Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans.
5/2006	Conformational properties of a phototautomerizable nucleoside biomarker for phenolic carcinogen exposure.
9/2004	Evidence for covalent DNA adduction by ochratoxin A following chronic exposure to rat and subacute exposure to pig.
7/2003	An oxygen-bonded c8-deoxyguanosine nucleoside adduct of pentachlorophenol by peroxidase activation: evidence for ambident c8 reactivity by phenoxyl radicals.

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Richard A Manderville Research Topics

Disease

10	Neoplasms (Cancer) 01/2021 - 05/2002
7	Carcinogenesis 01/2018 - 07/2003
1	Chronic Renal Insufficiency 01/2018
1	Carcinoma (Carcinomatosis) 01/2010
1	Mycotoxicosis (Fungus Poisoning) 06/2008
1	Kidney Diseases (Kidney Disease) 06/2008
1	Balkan Nephropathy (Balkan Endemic Nephropathy) 09/2004
1	Urologic Neoplasms (Urological Cancer) 09/2004
1	Leukemia 07/2003

Drug/Important Bio-Agent (IBA)

6	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2004
5	ochratoxin AIBA 01/2018 - 09/2004
3	CarcinogensIBA 06/2008 - 09/2004
2	MycotoxinsIBA 04/2012 - 09/2004
1	ProdigiosinIBA 10/2006
1	AlkaloidsIBA 10/2006
1	Phenol (Carbolic Acid)FDA Link 05/2006
1	MethylcholanthreneIBA 11/2005
1	phenoxy radicalIBA 09/2004
1	DNA AdductsIBA 07/2003
1	PyrrolesIBA 05/2002
1	Cytochrome P-450 CYP2B1 (PROD)IBA 05/2002
1	Protons (Proton)IBA 05/2002
1	acetonitrileIBA 05/2002