Ziad Mallat Selected Research

Cytokines

12/2020	IL-33 induces type-2-cytokine phenotype but exacerbates cardiac remodeling post-myocardial infarction with eosinophil recruitment, worsened systolic dysfunction, and ventricular wall rupture.
1/2020	2019 ATVB Plenary Lecture: Interleukin-2 Therapy in Cardiovascular Disease: The Potential to Regulate Innate and Adaptive Immunity.
1/2020	Thymic stromal lymphopoietin is a key cytokine for the immunomodulation of atherogenesis with Freund's adjuvant.
10/2018	Conflicting vascular and metabolic impact of the IL-33/sST2 axis.
8/2015	Colchicine Acutely Suppresses Local Cardiac Production of Inflammatory Cytokines in Patients With an Acute Coronary Syndrome.
2/2015	IL-17 and Th17 cells in atherosclerosis: subtle and contextual roles.
1/2014	Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice.
12/2013	Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.
5/2011	Recent advances on the role of cytokines in atherosclerosis.
9/2009	Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis.

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Ziad Mallat Research Topics

Disease

94	Atherosclerosis 01/2024 - 05/2002
37	Inflammation (Inflammations) 02/2024 - 10/2003
20	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 05/2007
16	Atherosclerotic Plaque (Atheroma) 01/2021 - 10/2002
15	Myocardial Infarction 11/2021 - 10/2005
14	Rupture 11/2022 - 03/2003
11	Aneurysm (Aneurysms) 01/2022 - 02/2010
11	Abdominal Aortic Aneurysm 01/2021 - 06/2011
9	Coronary Artery Disease (Coronary Atherosclerosis) 11/2021 - 10/2005
8	Acute Coronary Syndrome 10/2022 - 10/2005
6	Thrombosis (Thrombus) 01/2019 - 03/2003
5	Autoimmune Diseases (Autoimmune Disease) 12/2023 - 10/2010
5	Infarction (Infarctions) 01/2021 - 03/2013
5	Heart Failure 12/2020 - 11/2004
5	Coronary Disease (Coronary Heart Disease) 11/2018 - 11/2009
4	Aortic Dissection 11/2022 - 01/2016
4	Infections 11/2019 - 10/2007
4	Aortic Rupture 01/2019 - 12/2011
4	Aortic Aneurysm (Aneurysm, Aortic) 01/2019 - 02/2010
4	Ischemia 10/2009 - 09/2002
3	Heart Diseases (Heart Disease) 10/2022 - 10/2007
3	Disease Progression 01/2022 - 09/2015
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022 - 11/2004
3	Neoplasms (Cancer) 01/2022 - 12/2014
3	Hypercholesterolemia 07/2017 - 04/2008
3	Alzheimer Disease (Alzheimer's Disease) 01/2017 - 06/2002
3	Stroke (Strokes) 09/2011 - 02/2006
2	Endotoxemia 11/2023 - 01/2018
2	Non-ST Elevated Myocardial Infarction 10/2022 - 12/2012
2	ST Elevation Myocardial Infarction 10/2022 - 01/2022
2	Unstable Angina 10/2022 - 02/2012
2	Ischemic Stroke 11/2021 - 10/2018
2	Ventricular Remodeling 01/2021 - 01/2018
2	Necrosis 12/2020 - 10/2018
2	Obesity 10/2018 - 01/2018
2	Hypertension (High Blood Pressure) 10/2018 - 01/2017
2	Insulin Resistance 01/2018 - 01/2009
2	Metabolic Diseases (Metabolic Disease) 01/2018 - 01/2015
2	Reperfusion Injury 01/2018 - 11/2004

Drug/Important Bio-Agent (IBA)

18	Apolipoproteins E (ApoE)IBA 01/2023 - 02/2003
17	Secretory Phospholipases A2IBA 11/2021 - 10/2005
15	CholesterolIBA 01/2022 - 05/2002
15	CytokinesIBA 12/2020 - 10/2002
13	LDL Receptors (LDL Receptor)IBA 01/2021 - 08/2004
12	ApolipoproteinsIBA 01/2020 - 09/2003
11	Interleukin-10 (Interleukin 10)IBA 12/2023 - 08/2004
10	Angiotensin IIIBA 01/2022 - 02/2010
10	CollagenIBA 07/2017 - 10/2002
9	Biomarkers (Surrogate Marker)IBA 02/2024 - 04/2006
9	LipidsIBA 01/2023 - 02/2006
9	Lipoproteins (Lipoprotein)IBA 01/2019 - 10/2010
8	AntibodiesIBA 01/2024 - 06/2011
8	EnzymesIBA 03/2019 - 02/2012
8	Phospholipases (Phospholipase)IBA 10/2015 - 11/2010
7	InterleukinsIBA 12/2020 - 08/2008
7	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019 - 10/2002
7	oxidized low density lipoproteinIBA 01/2017 - 04/2007
7	Interleukin-17 (Interleukin 17)IBA 02/2015 - 09/2009
5	C-Reactive ProteinIBA 10/2022 - 08/2008
5	Interleukin-2 (IL2)IBA 10/2022 - 01/2018
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 09/2002
5	LigandsIBA 12/2020 - 12/2002
5	Immunoglobulin M (IgM)IBA 01/2019 - 10/2011
5	1-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA 05/2014 - 09/2011
5	Transforming Growth Factor beta (TGF-beta)IBA 12/2013 - 10/2002
4	Interleukin-18 (Interleukin 18)IBA 01/2024 - 09/2002
4	Phosphotransferases (Kinase)IBA 11/2023 - 01/2015
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2004
4	AntigensIBA 11/2019 - 02/2006
4	InflammasomesIBA 01/2019 - 04/2014
4	Peptides (Polypeptides)IBA 12/2016 - 06/2002
3	LDL Lipoproteins (beta Lipoproteins)IBA 01/2021 - 12/2012
3	Interleukin-33IBA 12/2020 - 10/2018
3	MicroRNAs (MicroRNA)IBA 07/2019 - 01/2014
3	Pancreatic Elastase (Elastase)IBA 01/2019 - 09/2017
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 08/2015
3	Immunoglobulin G (IgG)IBA 01/2019 - 10/2011
3	Metalloproteases (Metalloproteinases)IBA 01/2018 - 08/2008
3	Monoclonal AntibodiesIBA 11/2017 - 08/2010
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2016 - 08/2008
3	Messenger RNA (mRNA)IBA 04/2014 - 11/2004
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2013 - 10/2002
3	ChemokinesIBA 05/2011 - 01/2005
2	aldesleukin (Proleukin)FDA Link 01/2022 - 01/2018
2	KynurenineIBA 01/2021 - 01/2018
2	Triglycerides (Triacylglycerol)IBA 11/2020 - 12/2012
2	EpitopesIBA 01/2019 - 12/2007
2	B-Cell Activating FactorIBA 11/2018 - 07/2012
2	B-Cell Activation Factor ReceptorIBA 11/2018 - 07/2012
2	Troponin T (Troponin T1)IBA 01/2018 - 09/2011
2	ErbB Receptors (EGF Receptor)IBA 01/2018 - 01/2018
2	Interleukin-22 (IL-22)IBA 01/2018 - 01/2018
2	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2018 - 09/2015
2	Tissue Inhibitor of Metalloproteinase-1IBA 09/2017 - 08/2008
2	Immunoglobulin E (IgE)IBA 07/2017 - 01/2017

Therapy/Procedure

13	Therapeutics 01/2022 - 12/2003
4	Ligation 01/2018 - 12/2003
3	Immunomodulation 01/2020 - 09/2004
3	Immunotherapy 11/2018 - 01/2016
2	Injections 01/2020 - 03/2013