Monica Locatelli Selected Research

Hemolytic Anemia

10/2012	Lack of the lectin-like domain of thrombomodulin worsens Shiga toxin-associated hemolytic uremic syndrome in mice.
7/2011	Alternative pathway activation of complement by Shiga toxin promotes exuberant C3a formation that triggers microvascular thrombosis.

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Monica Locatelli Research Topics

Disease

10	Diabetic Nephropathies (Diabetic Nephropathy) 11/2023 - 03/2013
8	Albuminuria 07/2022 - 03/2013
6	Proteinuria 02/2024 - 01/2013
6	Inflammation (Inflammations) 01/2023 - 10/2012
5	Hemolytic-Uremic Syndrome 01/2022 - 07/2008
4	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 07/2008
3	Fibrosis (Cirrhosis) 01/2023 - 01/2017
3	Thrombosis (Thrombus) 01/2022 - 07/2011
3	Chronic Renal Insufficiency 01/2020 - 03/2013
2	Neoplasms (Cancer) 12/2022 - 11/2009
2	Kidney Diseases (Kidney Disease) 07/2022 - 01/2021
2	Microvascular Rarefaction 07/2022 - 10/2019
2	Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency) 01/2021 - 01/2016
2	Dyslipidemias (Dyslipidemia) 01/2021 - 03/2013
2	Type 2 Diabetes Mellitus (MODY) 01/2020 - 03/2013
2	Hemolytic Anemia 10/2012 - 07/2011
2	Thrombocytopenia (Thrombopenia) 10/2012 - 07/2011
2	Diarrhea 10/2012 - 07/2011
1	Infections 02/2024
1	Membranous Glomerulonephritis (Membranous Nephropathy) 02/2024
1	Acne Vulgaris 12/2023
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2023
1	Diabetes Mellitus 10/2023
1	Lung Injury 01/2023
1	Intestinal Failure 01/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2022
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 10/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Cardiac Arrhythmias (Arrythmia) 10/2018
1	Nephrosis 01/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2016
1	Sclerosis 01/2016
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2015
1	Cysts 01/2015
1	Renal Insufficiency (Renal Failure) 01/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 10/2014
1	Body Weight (Weight, Body) 03/2013

Drug/Important Bio-Agent (IBA)

5	Complement System Proteins (Complement)IBA 02/2024 - 07/2011
4	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 11/2023 - 01/2016
4	Shiga Toxin (Shigella Toxin)IBA 01/2022 - 07/2011
3	Sirtuin 3IBA 10/2022 - 01/2020
3	AntioxidantsIBA 10/2014 - 11/2009
2	estropipate (Ogen)FDA LinkGeneric 01/2023 - 07/2011
2	FibrinIBA 01/2023 - 07/2011
2	LipidsIBA 07/2022 - 01/2021
2	nephrinIBA 01/2022 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2015
2	ThrombomodulinIBA 10/2012 - 07/2011
1	Dosage Forms (Dosage Form)IBA 12/2023
1	Thyroid HormonesIBA 10/2023
1	Protein Subunits (Protein Subunit)IBA 01/2023
1	SARS-CoV-2 spike proteinIBA 01/2023
1	Anthocyanins (Anthocyanin)IBA 12/2022
1	superoxide dismutase 2IBA 10/2022
1	NestinIBA 01/2022
1	empagliflozinIBA 01/2022
1	Blood Glucose (Blood Sugar)IBA 01/2022
1	Shiga Toxin 2IBA 01/2022
1	CER-001IBA 01/2021
1	honokiolIBA 01/2020
1	Conditioned Culture MediaIBA 01/2020
1	lanthionineIBA 10/2019
1	Angiotensin IIIBA 10/2019
1	Peptide Hydrolases (Proteases)FDA Link 10/2019
1	Lisinopril (Prinivil)FDA LinkGeneric 10/2019
1	Peptides (Polypeptides)IBA 10/2019
1	angiotensin I (1-7)IBA 10/2019
1	LigandsIBA 10/2019
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2019
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 10/2018
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 10/2018
1	Phosphotransferases (Kinase)IBA 10/2018
1	Connexin 43 (Connexin43)IBA 10/2018
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2018
1	Bovine Serum AlbuminIBA 01/2018
1	dapagliflozinIBA 01/2018
1	MicroRNAs (MicroRNA)IBA 01/2017
1	CholesterolIBA 01/2016
1	Lipoprotein-XIBA 01/2016
1	Fibronectins (Fibronectin)IBA 01/2016
1	Streptozocin (Streptozotocin)FDA Link 01/2016
1	CytokinesIBA 01/2016
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2016
1	Phosphatidylcholine-Sterol O-Acyltransferase (Lecithin Cholesterol Acyltransferase)IBA 01/2016
1	bindaritIBA 01/2015
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2015
1	clovamideIBA 10/2014
1	Transaminases (Aminotransferases)IBA 03/2013
1	TriterpenesIBA 03/2013
1	2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid ethyl amideIBA 03/2013
1	bardoxolone methylIBA 03/2013
1	bardoxoloneIBA 03/2013
1	Ramipril (Altace)FDA LinkGeneric 01/2013
1	Glycoproteins (Glycoprotein)IBA 10/2012
1	AnticoagulantsIBA 10/2012
1	LectinsIBA 10/2012
1	P-SelectinIBA 07/2011

Therapy/Procedure

3	Therapeutics 01/2018 - 01/2015
1	Parenteral Nutrition 01/2023
1	Home Parenteral Nutrition 01/2023