Jack Leslie Selected Research

obeticholic acid

10/2019

A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jack Leslie Research Topics

Disease

11	Fibrosis (Cirrhosis) 01/2021 - 12/2015
7	Neoplasms (Cancer) 03/2024 - 01/2016
5	Inflammation (Inflammations) 11/2023 - 01/2019
5	Carcinogenesis 11/2023 - 01/2016
4	Liver Diseases (Liver Disease) 01/2024 - 12/2015
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2021
3	Liver Cirrhosis (Hepatic Cirrhosis) 11/2020 - 01/2016
2	Insulin Resistance 11/2023 - 01/2021
2	Non-alcoholic Fatty Liver Disease 12/2021 - 01/2020
1	Melanoma (Melanoma, Malignant) 03/2024
1	Prostatic Neoplasms (Prostate Cancer) 03/2024
1	Cholestasis 01/2023
1	Neurobehavioral Manifestations 01/2023
1	Metabolic Diseases (Metabolic Disease) 01/2022
1	Obesity 01/2022
1	Carcinoma (Carcinomatosis) 10/2020
1	Adenoma (Adenomas) 10/2020
1	Hyperammonemia 01/2020
1	Alcoholic Fatty Liver 01/2020
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2020
1	Idiopathic Pulmonary Fibrosis 01/2020
1	Chronic Renal Insufficiency 02/2016
1	Reperfusion Injury 02/2016
1	Cicatrix (Scar) 01/2016

Drug/Important Bio-Agent (IBA)

4	LipidsIBA 12/2021 - 01/2016
2	CytokinesIBA 11/2023 - 01/2020
2	Transcription Factors (Transcription Factor)IBA 10/2023 - 01/2016
2	CholesterolIBA 01/2021 - 01/2020
2	Mitochondrial DNA (mtDNA)IBA 01/2021 - 10/2020
2	Bleomycin (Blenoxane)FDA LinkGeneric 12/2020 - 01/2020
2	Liposomes (Liposome)IBA 01/2017 - 01/2016
1	beta-Galactoside alpha-2,3-SialyltransferaseIBA 03/2024
1	Immune Checkpoint InhibitorsIBA 03/2024
1	LigandsIBA 03/2024
1	Sialic Acid Binding Immunoglobulin-like LectinsIBA 03/2024
1	SialyltransferasesIBA 03/2024
1	SynaptophysinIBA 01/2024
1	Interleukin-6 (Interleukin 6)IBA 11/2023
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 10/2023
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2023
1	Sorafenib (BAY 43-9006)FDA Link 12/2022
1	Bevacizumab (Avastin)FDA Link 01/2022
1	atezolizumabIBA 01/2022
1	Fatty Acids (Saturated Fatty Acids)IBA 12/2021
1	lenvatinibIBA 11/2021
1	Programmed Cell Death 1 ReceptorIBA 11/2021
1	Blood Glucose (Blood Sugar)IBA 01/2021
1	Sterol Regulatory Element Binding ProteinsIBA 01/2021
1	BuffersIBA 01/2021
1	AntioxidantsIBA 01/2021
1	Carbon Tetrachloride (Tetrachloromethane)IBA 11/2020
1	SmokeIBA 01/2020
1	AmmoniaIBA 01/2020
1	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2020
1	EnzymesIBA 01/2020
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 01/2020
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020
1	Urea (Carbamide)FDA LinkGeneric 01/2020
1	IntegrinsIBA 01/2020
1	ornithine phenylacetateIBA 01/2020
1	Platelet-Derived Growth FactorIBA 10/2019
1	Hydroxyproline (4 Hydroxyproline)IBA 10/2019
1	C.I. direct red 80IBA 10/2019
1	Transforming Growth Factor-beta Type I ReceptorIBA 10/2019
1	nintedanibIBA 10/2019
1	Transforming Growth Factor beta (TGF-beta)IBA 10/2019
1	Extracellular Matrix ProteinsIBA 10/2019
1	obeticholic acidIBA 10/2019
1	Coloring Agents (Dyes)IBA 01/2019
1	Histones (Histone)IBA 01/2017
1	Histone MethyltransferasesIBA 01/2017
1	3-deazaneplanocinIBA 01/2017
1	pepstatin (pepstatin A)IBA 02/2016
1	Peptide Hydrolases (Proteases)FDA Link 02/2016
1	Cathepsin DIBA 02/2016
1	Chloroquine (Aralen)FDA LinkGeneric 02/2016
1	Immunoglobulin FragmentsIBA 01/2016
1	Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA 12/2015
1	Deubiquitinating EnzymesIBA 12/2015
1	LDN 57444IBA 12/2015

Therapy/Procedure

10	Therapeutics 03/2024 - 01/2016
3	Ligation 01/2023 - 12/2015
1	Drug Therapy (Chemotherapy) 10/2023
1	Immunotherapy 01/2022
1	Bioreactors (Bioreactor) 10/2019