Valerio Leoni Selected Research

citraconic acid (mesaconic acid)

11/2019

Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol.

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Valerio Leoni Research Topics

Disease

16	Huntington Disease (Huntington's Disease) 01/2023 - 09/2007
15	Neoplasms (Cancer) 01/2024 - 02/2016
13	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 04/2006
12	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 11/2008
9	Infections 03/2024 - 12/2008
9	Cognitive Dysfunction 01/2023 - 04/2006
8	Mitochondrial Diseases (Mitochondrial Disease) 03/2024 - 04/2014
6	Hypercholesterolemia 03/2024 - 09/2010
6	COVID-19 03/2024 - 01/2020
6	Inflammation (Inflammations) 01/2024 - 07/2006
6	Multiple Sclerosis 01/2021 - 10/2002
5	Atrophy 08/2015 - 01/2009
5	Disease Progression 08/2015 - 11/2008
4	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2017
3	Neuroinflammatory Diseases 04/2024 - 02/2005
3	Myocardial Ischemia (Ischemic Heart Diseases) 03/2024 - 12/2016
3	Ischemia 03/2024 - 10/2017
3	Obesity 09/2022 - 12/2016
3	Demyelinating Diseases (Demyelinating Disease) 01/2019 - 04/2003
2	Reperfusion Injury 03/2024 - 09/2022
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 01/2021
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2022 - 01/2021
2	Neoplasm Metastasis (Metastasis) 07/2018 - 01/2017
1	Heart Failure 05/2024
1	Down Syndrome (Down's Syndrome) 04/2024
1	Coronary Disease (Coronary Heart Disease) 01/2024
1	Communicable Diseases (Infectious Diseases) 01/2024
1	Myocardial Infarction 09/2022
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Chronic Hepatitis B 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Macular Degeneration (Age-Related Maculopathy) 01/2021
1	Adrenocortical Carcinoma 01/2020
1	Common Cold 01/2020
1	Relapsing-Remitting Multiple Sclerosis 11/2019
1	Hypertrophy 01/2019

Drug/Important Bio-Agent (IBA)

32	CholesterolIBA 04/2024 - 02/2005
22	OxysterolsIBA 03/2024 - 10/2002
12	24-hydroxycholesterolIBA 01/2024 - 10/2002
12	Biomarkers (Surrogate Marker)IBA 12/2022 - 04/2003
9	Proteins (Proteins, Gene)FDA Link 03/2024 - 09/2007
6	LigandsIBA 03/2024 - 06/2013
6	Apolipoproteins E (ApoE)IBA 11/2022 - 09/2007
6	27-hydroxycholesterolIBA 01/2022 - 01/2011
5	7-ketocholesterolIBA 01/2021 - 02/2005
4	VaccinesIBA 03/2024 - 01/2018
4	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2017
4	human ERBB2 proteinIBA 01/2018 - 01/2017
3	ApolipoproteinsIBA 11/2022 - 09/2010
3	LipidsIBA 01/2021 - 03/2012
3	Adenosine Triphosphate (ATP)IBA 10/2018 - 04/2014
2	SterolsIBA 03/2024 - 10/2017
2	4'-chlorodiazepamIBA 03/2024 - 10/2017
2	AntibodiesIBA 03/2024 - 01/2022
2	Mitochondrial Permeability Transition PoreIBA 09/2022 - 06/2013
2	Phosphotransferases (Kinase)IBA 09/2022 - 01/2019
2	AntigensIBA 01/2021 - 10/2019
2	Complement System Proteins (Complement)IBA 01/2021 - 11/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2019
2	Interleukin-12 (IL 12)IBA 01/2021 - 01/2018
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2019 - 10/2018
2	AcidsIBA 11/2019 - 01/2017
2	Cardiolipins (Cardiolipin)IBA 11/2019 - 10/2018
2	Messenger RNA (mRNA)IBA 10/2018 - 10/2007
2	Liver X ReceptorsIBA 07/2018 - 01/2017
2	Immune Checkpoint InhibitorsIBA 01/2018 - 01/2017
2	Acetyl Coenzyme A (Acetyl-CoA)IBA 08/2015 - 04/2014
1	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2024
1	steroidogenic acute regulatory proteinIBA 03/2024
1	Immunoglobulin A (IgA)IBA 03/2024
1	Lipoprotein(a)IBA 01/2024
1	C-Reactive ProteinIBA 01/2024
1	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 12/2022
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 09/2022
1	Estrogen ReceptorsIBA 01/2022
1	BNT162 VaccineIBA 01/2022
1	Dopamine Receptors (Dopamine Receptor)IBA 11/2021
1	Hepatitis B e AntigensIBA 01/2021
1	25-hydroxycholesterolIBA 01/2021
1	immune RNA (I-RNA)IBA 01/2021
1	CoagulantsIBA 01/2021
1	CytokinesIBA 01/2021
1	Lipocalin-2IBA 01/2021
1	Mitotane (Lysodren)FDA Link 01/2020
1	Dimethyl FumarateIBA 11/2019
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 11/2019
1	citraconic acid (mesaconic acid)IBA 11/2019
1	Caspase 3 (Caspase-3)IBA 11/2019
1	IntegrinsIBA 10/2019
1	NeuropeptidesIBA 09/2019
1	Anthocyanins (Anthocyanin)IBA 01/2019
1	Biotin (Vitamin H)FDA Link 01/2019
1	Small Heat-Shock ProteinsIBA 01/2019
1	tempolIBA 01/2019
1	PlasmalogensIBA 10/2018

Therapy/Procedure

7	Therapeutics 03/2024 - 01/2013
2	Immunotherapy 10/2019 - 01/2018
1	Intravenous Administration 08/2023
1	Injections 10/2021
1	Prostatectomy (Retropubic Prostatectomy) 01/2019