Shaoqing Lei Selected Research

Caveolin 3

8/2021	Selective inhibition of PKCβ2 improves Caveolin-3/eNOS signaling and attenuates lipopolysaccharide-induced injury by inhibiting autophagy in H9C2 cardiomyocytes.
8/2015	Inhibition of PKCβ2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling.
7/2013	Hyperglycemia-induced protein kinase C β2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling.

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Shaoqing Lei Research Topics

Disease

19	Hypoxia (Hypoxemia) 11/2023 - 05/2013
17	Myocardial Ischemia (Ischemic Heart Diseases) 05/2024 - 01/2011
15	Reperfusion Injury 07/2023 - 01/2011
8	Ischemia 05/2022 - 04/2011
8	Myocardial Infarction 01/2022 - 01/2011
7	Infarction (Infarctions) 05/2024 - 01/2011
7	Hyperglycemia 08/2021 - 03/2012
6	Lung Injury 10/2019 - 05/2013
4	Hypertrophy 08/2014 - 02/2012
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2023 - 08/2014
3	Inflammation (Inflammations) 05/2022 - 05/2013
3	Sepsis (Septicemia) 08/2021 - 11/2018
2	Type 2 Diabetes Mellitus (MODY) 11/2023 - 01/2022
2	Wounds and Injuries (Trauma) 12/2022 - 04/2011
2	Cardiomegaly (Heart Hypertrophy) 10/2016 - 08/2014
2	Diabetic Cardiomyopathies 07/2013 - 07/2012
2	Diabetes Complications 07/2012 - 03/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2024
1	Diabetes Mellitus 07/2023
1	COVID-19 01/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021
1	Thrombocytopenia (Thrombopenia) 10/2020
1	Acute Kidney Injury (Acute Renal Failure) 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 10/2018
1	Liver Neoplasms (Liver Cancer) 10/2018
1	Acute Lung Injury 01/2018
1	Coronary Occlusion 03/2016

Drug/Important Bio-Agent (IBA)

15	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 10/2013
7	Streptozocin (Streptozotocin)FDA Link 11/2023 - 10/2011
6	AntioxidantsIBA 01/2022 - 01/2011
5	Heme Oxygenase-1IBA 10/2019 - 04/2011
5	8-epi-prostaglandin F2alphaIBA 01/2019 - 06/2011
5	Acetylcysteine (Siran)FDA LinkGeneric 01/2019 - 01/2011
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 06/2011
4	CytokinesIBA 01/2018 - 04/2011
4	Proteins (Proteins, Gene)FDA Link 08/2014 - 01/2011
3	LipopolysaccharidesIBA 08/2021 - 11/2018
3	Caveolin 3IBA 08/2021 - 07/2013
3	4,5-dianilinophthalimideIBA 01/2020 - 08/2015
3	5,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA 01/2020 - 03/2016
3	Remifentanil (Ultiva)FDA Link 01/2019 - 03/2016
3	salicylhydroxamic acid (SHAM)IBA 03/2016 - 01/2011
3	Caspase 3 (Caspase-3)IBA 08/2014 - 01/2011
3	Allopurinol (Remid)FDA LinkGeneric 10/2013 - 01/2011
2	MB Form Creatine KinaseIBA 05/2022 - 03/2016
2	Sirtuin 1IBA 01/2022 - 01/2019
2	Small Interfering RNA (siRNA)IBA 01/2021 - 05/2013
2	Oxygen (Dioxygen)IBA 10/2019 - 04/2011
2	WortmanninIBA 01/2019 - 03/2016
2	alpha- cyano- (3,4- dihydroxy)- N- benzylcinnamideIBA 01/2019 - 03/2016
2	InflammasomesIBA 01/2019 - 01/2017
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2016 - 10/2013
2	Phosphotransferases (Kinase)IBA 03/2016 - 01/2011
2	CreatinineIBA 03/2016 - 01/2011
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 03/2016 - 08/2014
2	ginsenoside Rb1IBA 01/2015 - 10/2011
2	Malondialdehyde (Propanedial)IBA 08/2014 - 05/2013
1	Therapeutic UsesIBA 05/2024
1	Protein Deglycase DJ-1IBA 05/2024
1	GlycolipidsIBA 07/2023
1	nobiletinIBA 07/2023
1	SR9009IBA 10/2022
1	maslinic acidIBA 05/2022
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2022
1	trans-crotonin (CTN)IBA 01/2022
1	histone deacetylase 3IBA 01/2022
1	mitoquinoneIBA 01/2022
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2022
1	Protein Isoforms (Isoforms)IBA 08/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	ProcalcitoninIBA 10/2020
1	Troponin IIBA 10/2020
1	Dexmedetomidine FDA Link 10/2019
1	NitrogenIBA 10/2019
1	Hormones (Hormone)IBA 01/2019
1	interleukin-1beta-converting enzyme inhibitorIBA 01/2019
1	MelatoninIBA 01/2019
1	CyclodextrinsIBA 01/2019
1	N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketoneIBA 01/2019
1	LipidsIBA 01/2019
1	Opioid Receptors (Opioid Receptor)IBA 11/2018
1	DiosgeninIBA 10/2018
1	Superoxide DismutaseIBA 01/2018
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2018
1	PeroxiredoxinsIBA 01/2018
1	Beclin-1IBA 01/2018
1	tubastatin AIBA 01/2018
1	MicroRNAs (MicroRNA)IBA 10/2017
1	Nitric Oxide Synthase (NO Synthase)IBA 10/2016
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 03/2016
1	SB 216763IBA 03/2016
1	Janus Kinase 2IBA 03/2016
1	RNA (Ribonucleic Acid)IBA 03/2016
1	Glycogen Synthase (Synthase I)IBA 03/2016

Therapy/Procedure

3	Ischemic Postconditioning 05/2024 - 04/2011
2	Intraperitoneal Injections 11/2023 - 01/2022
1	Length of Stay 01/2021
1	Mechanical Ventilators (Ventilator) 01/2017
1	Craniotomy 01/2017
1	Artificial Respiration (Mechanical Ventilation) 01/2017