John J Lehman Selected Research

PPAR gamma

2/2012	Chronic caloric restriction attenuates a loss of sulfatide content in PGC-1α-/- mouse cortex: a potential lipidomic role of PGC-1α in neurodegeneration.
3/2004	Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.

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John J Lehman Research Topics

Disease

4	Cardiomyopathies (Cardiomyopathy) 02/2009 - 01/2002
2	Heart Failure 02/2009 - 04/2002
2	Cardiomegaly (Heart Hypertrophy) 04/2002 - 04/2002
2	Hypertrophy 04/2002 - 01/2002
1	Obesity 02/2012
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 02/2009
1	Mitochondrial Diseases (Mitochondrial Disease) 02/2009
1	Diabetes Mellitus 01/2002
1	Ventricular Dysfunction 01/2002
1	Diabetic Cardiomyopathies 01/2002

Drug/Important Bio-Agent (IBA)

3	PPAR alphaIBA 04/2002 - 01/2002
2	PPAR gammaIBA 02/2012 - 03/2004
2	DNA (Deoxyribonucleic Acid)IBA 02/2009 - 04/2002
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2002 - 01/2002
2	EnzymesIBA 04/2002 - 04/2002
2	Glucose (Dextrose)FDA LinkGeneric 04/2002 - 01/2002
1	LipidsIBA 02/2012
1	ERRalpha Estrogen-Related ReceptorIBA 02/2009
1	Adenosine Triphosphate (ATP)IBA 07/2008
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 04/2002
1	Mitogen-Activated Protein KinasesIBA 04/2002
1	Transcription Factors (Transcription Factor)IBA 04/2002
1	Nuclear Proteins (Protein, Nuclear)IBA 04/2002
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2002