Martin Lefkowitz Selected Research

Aldosterone

9/2012

The effects of aldosterone synthase inhibition on aldosterone and cortisol in patients with hypertension: a phase II, randomized, double-blind, placebo-controlled, multicenter study.

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Martin Lefkowitz Research Topics

Disease

47	Heart Failure 03/2024 - 10/2012
5	Myocardial Infarction 12/2022 - 01/2018
5	Hypertension (High Blood Pressure) 04/2014 - 09/2004
3	Abdominal Pain (Pain, Abdominal) 04/2003 - 05/2002
3	Constipation 04/2003 - 05/2002
2	Cardiomyopathies (Cardiomyopathy) 04/2024 - 10/2020
2	Hypotension (Low Blood Pressure) 03/2024 - 01/2018
2	Left Ventricular Dysfunction 12/2022 - 02/2015
2	Cardiac Sudden Death (Sudden Cardiac Arrest) 10/2020 - 08/2015
2	Isolated Systolic Hypertension 01/2007 - 09/2004
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 09/2002 - 05/2002
1	Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve) 10/2022
1	Chronic Kidney Failure (Chronic Renal Failure) 10/2022
1	Hypoglycemia (Reactive Hypoglycemia) 01/2022
1	Atrial Fibrillation 01/2022
1	Sudden Death 12/2021
1	ST Elevation Myocardial Infarction 01/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Confusion (Bewilderment) 01/2019
1	Inflammation (Inflammations) 01/2018
1	Chronic Renal Insufficiency 01/2018
1	Hyperkalemia 01/2017
1	Insulin Resistance 01/2017
1	Dyspnea (Shortness of Breath) 01/2017
1	Renal Insufficiency (Renal Failure) 01/2017
1	Diabetes Mellitus 02/2016
1	Human Influenza (Influenza) 02/2016
1	Hypertrophy 12/2014
1	Angioedema 04/2014
1	Stroke (Strokes) 01/2007
1	Acute Coronary Syndrome 01/2007
1	Kidney Diseases (Kidney Disease) 09/2004
1	Diarrhea 05/2002
1	Dehydration (Water Stress) 05/2002

Drug/Important Bio-Agent (IBA)

38	sacubitril and valsartan sodium hydrate drug combinationIBA 03/2024 - 10/2012
16	Neprilysin (Neutral Endopeptidase)IBA 12/2022 - 10/2012
14	Angiotensin Receptors (Angiotensin II Receptor)IBA 12/2022 - 10/2012
13	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 12/2022 - 02/2015
11	Enalapril FDA LinkGeneric 01/2022 - 07/2014
10	paragonIBA 03/2024 - 01/2020
9	Valsartan (Vals)FDA Link 03/2024 - 10/2012
6	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2023 - 06/2014
4	Ramipril (Altace)FDA LinkGeneric 12/2022 - 11/2021
4	pro-brain natriuretic peptide (1-76)IBA 01/2019 - 10/2012
3	Natriuretic PeptidesIBA 01/2023 - 07/2014
3	Angiotensin Receptor AntagonistsIBA 12/2021 - 06/2014
3	tegaserod (Zelnorm)FDA Link 04/2003 - 05/2002
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2023 - 01/2019
2	DiureticsIBA 01/2023 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 11/2022 - 01/2016
2	Serotonin (5 Hydroxytryptamine)IBA 09/2002 - 05/2002
1	Insulin (Novolin)FDA Link 01/2022
1	SodiumIBA 12/2021
1	sacubitrilIBA 11/2021
1	AngiotensinsIBA 01/2021
1	CreatinineIBA 01/2021
1	ReninIBA 01/2021
1	Troponin T (Troponin T1)IBA 01/2021
1	Trinitrotoluene (TNT)IBA 01/2021
1	Therapeutic UsesIBA 01/2020
1	C-Reactive ProteinIBA 01/2018
1	canakinumab FDA Link 01/2018
1	InterleukinsIBA 01/2018
1	InflammasomesIBA 01/2018
1	Monoclonal AntibodiesIBA 01/2018
1	PotassiumIBA 01/2017
1	Mineralocorticoid Receptor AntagonistsIBA 01/2017
1	Influenza Vaccines (Influenza Vaccine)FDA Link 02/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2016
1	CollagenIBA 01/2016
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2016
1	Galectin 3 (LGALS3)IBA 01/2016
1	candesartanIBA 02/2015
1	Adrenocorticotropic Hormone (ACTH)FDA Link 09/2012
1	Hydrocortisone (Cortisol)FDA LinkGeneric 09/2012
1	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 09/2012
1	OsilodrostatIBA 09/2012
1	AldosteroneIBA 09/2012
1	TabletsIBA 01/2007
1	Antihypertensive Agents (Antihypertensives)IBA 09/2004
1	benazepril (Briem)FDA LinkGeneric 09/2004
1	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 09/2004
1	Amlodipine (Norvasc)FDA LinkGeneric 09/2004
1	PlacebosIBA 05/2002
1	ElectrolytesIBA 05/2002

Therapy/Procedure

18	Therapeutics 01/2023 - 05/2002
2	Percutaneous Coronary Intervention 01/2021 - 01/2007
2	Patient Readmission 01/2017 - 01/2016
1	Polypharmacy 04/2024
1	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 10/2020
1	Drug Tapering 01/2019
1	Artificial Respiration (Mechanical Ventilation) 01/2017
1	Defibrillators (Defibrillator) 02/2016
1	Investigational Therapies (Experimental Therapy) 02/2015
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2007