Ana S Leal Selected Research

bardoxolone

12/2016

The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer.

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Ana S Leal Research Topics

Disease

21	Neoplasms (Cancer) 12/2023 - 09/2012
7	Pancreatic Neoplasms (Pancreatic Cancer) 12/2020 - 09/2012
5	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 12/2023 - 01/2019
5	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2017
4	Inflammation (Inflammations) 12/2023 - 01/2017
3	Carcinogenesis 01/2023 - 01/2019
2	Lung Neoplasms (Lung Cancer) 10/2021 - 01/2018
2	Pancreatitis 12/2020 - 12/2018
2	Neoplasm Metastasis (Metastasis) 10/2018 - 01/2017
1	Hypertriglyceridemia 12/2020
1	Triple Negative Breast Neoplasms 01/2019
1	Hepatomegaly 01/2019
1	Alopecia (Baldness) 01/2019
1	Weight Loss (Weight Reduction) 01/2017

Drug/Important Bio-Agent (IBA)

8	Bexarotene (LGD1069)FDA Link 12/2023 - 01/2019
6	Retinoid X Receptors (Retinoid X Receptor)IBA 12/2023 - 01/2019
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2023 - 01/2021
3	LigandsIBA 12/2023 - 01/2019
3	TriterpenesIBA 01/2023 - 12/2016
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2017
2	CarcinogensIBA 03/2023 - 01/2019
2	Interleukin-6 (Interleukin 6)IBA 01/2023 - 01/2017
2	AntibodiesIBA 10/2021 - 01/2019
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2019
2	LG 100268IBA 01/2019 - 01/2019
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2019 - 01/2017
2	talazoparibIBA 01/2019 - 01/2017
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2018 - 01/2017
2	oleananeIBA 12/2017 - 02/2013
2	CytokinesIBA 01/2017 - 12/2016
2	imidazoleIBA 02/2013 - 09/2012
2	Ursolic AcidIBA 10/2012 - 09/2012
1	Transcription Factors (Transcription Factor)IBA 12/2023
1	RNA (Ribonucleic Acid)IBA 02/2023
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023
1	bardoxolone methylIBA 01/2023
1	vinyl carbamateIBA 10/2021
1	INCB057643IBA 12/2020
1	CholesterolIBA 01/2019
1	Liposomes (Liposome)IBA 01/2019
1	LG 268IBA 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	OligopeptidesIBA 12/2018
1	CeruletideIBA 12/2018
1	EnzymesIBA 12/2018
1	OximesIBA 10/2018
1	Protein Isoforms (Isoforms)IBA 10/2018
1	Cyclin D1IBA 10/2018
1	Phosphotransferases (Kinase)IBA 10/2018
1	friedelaneIBA 12/2017
1	ursaneIBA 12/2017
1	quinone methideIBA 12/2017
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2017
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	1- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA 12/2016
1	bardoxoloneIBA 12/2016
1	CarbamatesIBA 02/2013
1	Oleanolic AcidIBA 02/2013
1	compound 20IBA 09/2012

Therapy/Procedure

3	Therapeutics 01/2021 - 01/2017
2	Immunomodulation 01/2021 - 01/2019
1	Immunotherapy 10/2021
1	Chemoprevention 01/2018