Young-Lan Kwak Selected Research

Reperfusion Injury

3/2024	Effect of high-dose vitamin C on renal ischemia-reperfusion injury.
1/2022	Effects of intraoperative dexmedetomidine infusion on renal function in elective living donor kidney transplantation: a randomized controlled trial.
1/2020	Effect of dexmedetomidine on acute kidney injury after aortic surgery: a single-centre, placebo-controlled, randomised controlled trial.
1/2020	Age-Related Difference in the Effect of Acute Hyperglycemia on Myocardial Ischemia-Reperfusion Injury.
1/2019	Protective Effect of Ethyl Pyruvate against Myocardial Ischemia Reperfusion Injury through Regulations of ROS-Related NLRP3 Inflammasome Activation.
2/2018	Ethyl pyruvate attenuates myocardial ischemia-reperfusion injury exacerbated by hyperglycemia via retained inhibitory effect on HMGB1.
1/2018	Ethyl pyruvate is renoprotective against ischemia-reperfusion injury under hyperglycemia.
12/2017	Effects of remote ischemic preconditioning in patients with concentric myocardial hypertrophy: A randomized, controlled trial with molecular insights.
1/2016	Protective Effect of Peroxisome Proliferator-Activated Receptor α Activation against Cardiac Ischemia-Reperfusion Injury Is Related to Upregulation of Uncoupling Protein-3.
12/2014	Erythropoietin protects myocardium against ischemia-reperfusion injury under moderate hyperglycemia.

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Young-Lan Kwak Research Topics

Disease

15	Reperfusion Injury 03/2024 - 02/2010
15	Acute Kidney Injury (Acute Renal Failure) 03/2024 - 10/2013
12	Inflammation (Inflammations) 03/2024 - 09/2009
9	Myocardial Infarction 01/2023 - 08/2008
6	Ischemia 03/2024 - 08/2012
6	Stroke (Strokes) 01/2023 - 01/2017
6	Hyperglycemia 01/2020 - 08/2013
6	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019 - 01/2013
5	Anemia 12/2022 - 11/2011
5	Hypoxia (Hypoxemia) 01/2019 - 01/2013
4	Hemorrhage 04/2020 - 12/2010
4	Pain (Aches) 04/2019 - 02/2016
3	Endocarditis 04/2024 - 09/2009
3	Neoplasms (Cancer) 01/2023 - 05/2021
3	Necrosis 05/2021 - 05/2014
3	Heart Failure 01/2021 - 10/2007
3	Delirium 08/2020 - 10/2017
3	Respiratory Insufficiency (Respiratory Failure) 01/2018 - 09/2007
3	Aortic Valve Stenosis (Aortic Stenosis) 12/2017 - 05/2013
3	Thrombophilia 01/2014 - 09/2009
2	Hypertension (High Blood Pressure) 03/2023 - 01/2014
2	Infections 12/2020 - 01/2017
2	Mitral Valve Insufficiency (Mitral Regurgitation) 02/2020 - 10/2007
2	Nausea 10/2016 - 02/2016
2	Postoperative Nausea and Vomiting (PONV) 10/2016 - 02/2016
2	Cardiomyopathies (Cardiomyopathy) 08/2008 - 10/2007
2	Left Ventricular Dysfunction 06/2008 - 09/2007
1	Critical Illness (Critically Ill) 03/2024
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023
1	Lung Neoplasms (Lung Cancer) 01/2023
1	Iron Deficiencies 12/2022
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 12/2022
1	Hypothyroidism 08/2022
1	Postoperative Cognitive Complications 01/2022
1	Delayed Graft Function 01/2022
1	Colonic Neoplasms (Colon Cancer) 12/2021
1	Carcinogenesis 12/2021
1	Colorectal Neoplasms (Colorectal Cancer) 05/2021
1	Neoplasm Metastasis (Metastasis) 05/2021

Drug/Important Bio-Agent (IBA)

7	Dexmedetomidine FDA Link 04/2024 - 02/2016
5	Erythropoietin FDA Link 12/2014 - 11/2011
4	CreatinineIBA 03/2023 - 01/2018
4	Anesthetics (Anesthetic Agents)IBA 04/2019 - 08/2012
3	CytokinesIBA 05/2021 - 08/2012
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 08/2013
3	HMGB1 Protein (HMG1)IBA 01/2020 - 01/2017
3	ethyl pyruvateIBA 01/2019 - 01/2018
3	Analgesics (Analgesic Drugs)IBA 01/2018 - 02/2016
3	Hormones (Hormone)IBA 12/2014 - 01/2013
2	Oxygen (Dioxygen)IBA 01/2023 - 02/2010
2	Interleukin-18 (Interleukin 18)IBA 01/2023 - 01/2022
2	InflammasomesIBA 01/2023 - 01/2019
2	IronIBA 12/2022 - 01/2021
2	HepcidinsIBA 12/2022 - 01/2021
2	Cystatin CIBA 01/2022 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 05/2021 - 05/2014
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 08/2020 - 09/2016
2	Glucose (Dextrose)FDA LinkGeneric 02/2020 - 01/2017
2	SympatholyticsIBA 01/2020 - 02/2016
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2013
2	Midazolam (Versed)FDA LinkGeneric 04/2019 - 01/2018
2	Remifentanil (Ultiva)FDA Link 04/2019 - 01/2018
2	propacetamolIBA 01/2018 - 10/2016
2	Sevoflurane (Ultane)FDA LinkGeneric 12/2017 - 08/2014
2	Heparin (Liquaemin)FDA LinkGeneric 10/2017 - 09/2009
2	Saline SolutionIBA 10/2016 - 08/2015
2	Fentanyl (Sublimaze)FDA LinkGeneric 10/2016 - 02/2016
2	salicylhydroxamic acid (SHAM)IBA 12/2014 - 08/2013
2	Propofol (Diprivan)FDA LinkGeneric 08/2014 - 08/2013
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 03/2024
1	AntioxidantsIBA 03/2024
1	Interleukin-10 (Interleukin 10)IBA 01/2023
1	Freund's AdjuvantIBA 12/2022
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 08/2022
1	InterleukinsIBA 01/2022
1	bisphenol AIBA 12/2021
1	Estrogens (Estrogen)FDA Link 12/2021
1	Endocrine DisruptorsIBA 12/2021
1	Carcinoembryonic AntigenIBA 05/2021
1	Ketamine FDA LinkGeneric 05/2021
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2021
1	Desflurane (I 653)FDA Link 05/2021

Therapy/Procedure

11	Cardiopulmonary Bypass (Heart-Lung Bypass) 03/2024 - 09/2007
10	Off-Pump Coronary Artery Bypass (Coronary Artery Bypass, Off Pump) 01/2023 - 09/2007
5	Therapeutics 12/2022 - 05/2013
5	Anesthesia 05/2021 - 08/2014
3	Artificial Respiration (Mechanical Ventilation) 01/2023 - 12/2020
3	Transcatheter Aortic Valve Replacement 09/2014 - 05/2013
2	Immunomodulation 01/2023 - 05/2021
2	Mechanical Ventilators (Ventilator) 01/2020 - 07/2018
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 07/2018 - 09/2007
2	Analgesia 01/2018 - 02/2016
2	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 10/2016 - 02/2016
2	Spinal Fusion (Spondylosyndesis) 02/2016 - 08/2015
2	Fluid Therapy (Oral Rehydration Therapy) 08/2015 - 05/2014
1	Lung Transplantation 01/2024
1	Nephrectomy 03/2023
1	Length of Stay 01/2023
1	Perioperative Period 01/2022
1	Kidney Transplantation 01/2022