Satoru Koyanagi Selected Research

Breast Neoplasms (Breast Cancer)

3/2024	Circadian rhythms in CYP2A5 expression underlie the time-dependent effect of tegafur on breast cancer.
1/2023	Modulation of cell physiology by bispecific nanobodies enabling changes in the intracellular localization of organelle proteins.
1/2021	Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
1/2021	Sulfasalazine alleviates neuropathic pain hypersensitivity in mice through inhibition of SGK-1 in the spinal cord.
1/2019	Dosing Time-Dependent Changes in the Anti-tumor Effect of xCT Inhibitor Erastin in Human Breast Cancer Xenograft Mice.
4/2018	Optimizing the dosing schedule of l-asparaginase improves its anti-tumor activity in breast tumor-bearing mice.
1/2018	Optimized Dosing Schedule Based on Circadian Dynamics of Mouse Breast Cancer Stem Cells Improves the Antitumor Effects of Aldehyde Dehydrogenase Inhibitor.
5/2012	Intestinal expression of mouse Abcg2/breast cancer resistance protein (BCRP) gene is under control of circadian clock-activating transcription factor-4 pathway.

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Satoru Koyanagi Research Topics

Disease

29	Neoplasms (Cancer) 03/2024 - 01/2003
10	Hypersensitivity (Allergy) 03/2024 - 11/2010
10	Neuralgia (Stump Neuralgia) 03/2024 - 11/2010
8	Breast Neoplasms (Breast Cancer) 03/2024 - 05/2012
7	Inflammation (Inflammations) 02/2024 - 08/2009
6	Pain (Aches) 03/2024 - 04/2011
6	Chronic Renal Insufficiency 02/2024 - 03/2016
6	Hyperalgesia 01/2023 - 11/2010
5	Hypoxia (Hypoxemia) 11/2018 - 11/2003
4	Heart Failure 02/2024 - 10/2022
4	Fibrosis (Cirrhosis) 02/2024 - 10/2012
4	Peripheral Nervous System Diseases (PNS Diseases) 08/2022 - 07/2015
3	Arthritis (Polyarthritis) 12/2023 - 04/2011
3	Stroke (Strokes) 12/2023 - 12/2008
3	Asthma (Bronchial Asthma) 12/2023 - 07/2010
3	Carcinogenesis 11/2019 - 01/2012
2	Allergic Rhinitis 12/2023 - 10/2022
2	Peptic Ulcer (Peptic Ulcers) 12/2023 - 10/2022
2	Myocardial Infarction 12/2023 - 10/2022
2	Diabetic Neuropathies (Diabetic Neuropathy) 01/2018 - 07/2015
2	Colonic Neoplasms (Colon Cancer) 12/2013 - 08/2010
2	Rheumatoid Arthritis 04/2013 - 04/2011
2	Experimental Arthritis 04/2013 - 04/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2011 - 08/2009
2	Pheochromocytoma 12/2008 - 04/2004
2	Leukemia 11/2008 - 12/2005
2	Neoplasm Metastasis (Metastasis) 11/2003 - 01/2003
2	Experimental Melanoma 05/2003 - 01/2003
2	Lewis Lung Carcinoma 05/2003 - 01/2003
2	Sarcoma 180 05/2003 - 01/2003
1	Acute Kidney Injury (Acute Renal Failure) 11/2023
1	Bacterial Infections (Bacterial Infection) 11/2023
1	Retinal Degeneration 01/2023
1	Nociceptive Pain 01/2023
1	Fibrosarcoma 01/2023
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2022
1	Sleep Wake Disorders 10/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 08/2022
1	Colorectal Neoplasms (Colorectal Cancer) 08/2022
1	Melanoma (Melanoma, Malignant) 01/2022
1	Hypertension (High Blood Pressure) 01/2021
1	Heart Diseases (Heart Disease) 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021

Drug/Important Bio-Agent (IBA)

12	Messenger RNA (mRNA)IBA 01/2014 - 11/2003
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2004
5	DNA (Deoxyribonucleic Acid)IBA 03/2016 - 12/2005
4	LigandsIBA 01/2023 - 10/2012
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2018 - 01/2003
3	Streptozocin (Streptozotocin)FDA Link 03/2024 - 07/2015
3	CytokinesIBA 02/2024 - 08/2009
3	Vancomycin FDA LinkGeneric 11/2023 - 04/2017
3	Aldehyde DehydrogenaseIBA 01/2021 - 01/2018
3	GlucocorticoidsIBA 01/2021 - 04/2006
3	Plasminogen Activator Inhibitor 1IBA 12/2011 - 12/2008
2	Fluorouracil (Carac)FDA LinkGeneric 03/2024 - 04/2008
2	ProdrugsIBA 03/2024 - 01/2021
2	human GPR68 proteinIBA 02/2024 - 01/2021
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2023 - 11/2010
2	Opioid Analgesics (Opioids)IBA 01/2023 - 11/2010
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 08/2022 - 08/2010
2	Analgesics (Analgesic Drugs)IBA 05/2022 - 07/2015
2	Sulfasalazine (Azulfidine)FDA LinkGeneric 08/2021 - 01/2021
2	Angiotensin IIIBA 01/2021 - 01/2018
2	EnzymesIBA 04/2018 - 05/2003
2	Liposomes (Liposome)IBA 01/2018 - 08/2010
2	Methotrexate (Mexate)FDA LinkGeneric 04/2011 - 12/2005
2	Plasminogen Activators (Plasminogen Activator)IBA 10/2010 - 04/2004
2	Irinotecan (Camptosar)FDA LinkGeneric 02/2009 - 04/2006
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 08/2008 - 11/2006
2	Methionine (L-Methionine)FDA Link 11/2004 - 02/2003
2	AminopeptidasesIBA 11/2004 - 02/2003
1	TegafurIBA 03/2024
1	Glucose (Dextrose)FDA LinkGeneric 03/2024
1	empagliflozinIBA 03/2024
1	SodiumIBA 03/2024
1	HomoharringtonineIBA 02/2024
1	Drinking WaterIBA 02/2024
1	EndocannabinoidsIBA 01/2024
1	Brain Natriuretic Peptide (Natrecor)FDA Link 10/2023
1	IndicanIBA 10/2023
1	Sulfates (Sulfates, Inorganic)IBA 10/2023
1	ChemokinesIBA 01/2023
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2023
1	CC ChemokinesIBA 01/2023
1	VimentinIBA 01/2023
1	Chemokine ReceptorsIBA 01/2023
1	Proton Pump InhibitorsIBA 08/2022
1	Omeprazole (Prilosec)FDA LinkGeneric 08/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Sulfapyridine FDA Link 01/2021
1	XenobioticsIBA 01/2021

Therapy/Procedure

11	Therapeutics 11/2023 - 11/2003
5	Oral Administration 03/2024 - 07/2015
5	Chronotherapy 12/2023 - 07/2010
4	Drug Therapy (Chemotherapy) 03/2024 - 11/2010
2	Nephrectomy 02/2024 - 01/2021
2	Ligation 01/2024 - 11/2010
1	Transjugular Intrahepatic Portasystemic Shunt 01/2023
1	Immunotherapy 01/2022
1	Spinal Injections 01/2021