Kenneth S Koblan Selected Research

Antidepressive Agents (Antidepressants)

1/2021

Discovery of Nonracemic Amisulpride to Maximize Benefit/Risk of 5-HT7 and D2 Receptor Antagonism for the Treatment of Mood Disorders.

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Kenneth S Koblan Research Topics

Disease

23	Schizophrenia (Dementia Praecox) 03/2024 - 11/2010
7	Migraine Disorders (Migraine) 11/2009 - 01/2002
6	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2020 - 07/2009
5	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2021 - 11/2015
4	Body Weight (Weight, Body) 01/2024 - 06/2009
4	Parkinson Disease (Parkinson's Disease) 08/2023 - 10/2008
4	Psychotic Disorders (Schizoaffective Disorder) 08/2023 - 01/2019
3	Bipolar Disorder (Manic Depressive Psychosis) 12/2022 - 01/2021
3	Pain (Aches) 11/2010 - 02/2003
3	Hyperalgesia 07/2007 - 02/2003
2	Binge-Eating Disorder (Binge Eating Disorder) 04/2024 - 01/2020
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2024 - 01/2024
2	Weight Gain 01/2024 - 06/2009
2	Obesity 01/2024 - 06/2009
2	Cognitive Dysfunction 08/2023 - 08/2023
2	Sleepiness 01/2023 - 01/2020
2	Alzheimer Disease (Alzheimer's Disease) 12/2022 - 11/2006
2	Major Depressive Disorder (Major Depressive Disorders) 10/2016 - 08/2013
2	Neuralgia (Stump Neuralgia) 07/2011 - 08/2002
1	Prediabetic State (Prediabetes) 03/2024
1	Nausea 08/2023
1	Hallucinations (Hallucination) 08/2023
1	Dizziness (Lightheadedness) 08/2023
1	Disorders of Excessive Somnolence (Hypersomnia) 08/2023
1	Confusion (Bewilderment) 08/2023
1	Cataplexy 01/2023
1	Narcolepsy 01/2023
1	Autistic Disorder (Autism) 12/2022
1	Substance-Related Disorders (Drug Abuse) 01/2022
1	Mood Disorders (Mood Disorder) 01/2021
1	Headache (Headaches) 01/2020
1	Bulimia (Binge Eating) 01/2020
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2020
1	Neurobehavioral Manifestations 10/2019
1	Epilepsy (Aura) 11/2010
1	Nervous System Diseases (Neurological Disorders) 11/2010
1	Hyperemia 11/2009
1	Coronary Artery Disease (Coronary Atherosclerosis) 11/2009
1	Myocardial Infarction 11/2009
1	Atrial Fibrillation 01/2009
1	Cardiac Arrhythmias (Arrythmia) 01/2009
1	Absence Epilepsy (Childhood Absence Epilepsy) 10/2008
1	Seizures (Absence Seizure) 10/2008
1	Essential Tremor (Essential Tremors) 10/2008

Drug/Important Bio-Agent (IBA)

18	SEP-363856IBA 03/2024 - 10/2019
14	Trace amine-associated receptor 1IBA 03/2024 - 01/2020
9	Antipsychotic Agents (Antipsychotics)IBA 03/2024 - 01/2018
8	Serotonin (5 Hydroxytryptamine)IBA 08/2023 - 11/2009
7	4- (3,4- dichlorophenyl)- 1,2,3,4- tetrahydronaphthalen- 1- amineIBA 04/2024 - 11/2015
7	5-HT1A Serotonin ReceptorIBA 08/2023 - 10/2016
6	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 02/2008 - 01/2002
5	Calcitonin Gene-Related PeptideIBA 02/2008 - 01/2002
4	Serotonin 5-HT1 Receptor AgonistsIBA 08/2023 - 10/2021
3	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 10/2023 - 10/2019
3	CarrageenanIBA 07/2007 - 02/2003
2	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 04/2024 - 08/2013
2	Triglycerides (Triacylglycerol)IBA 01/2024 - 12/2021
2	Lurasidone Hydrochloride FDA Link 10/2023 - 01/2018
2	Dopamine (Intropin)FDA LinkGeneric 08/2023 - 02/2016
2	Amisulpride (Solian)IBA 01/2022 - 01/2021
2	T-Type Calcium Channels (T-Type Calcium Channel)IBA 11/2010 - 06/2009
2	olcegepantIBA 02/2008 - 01/2002
2	piperidineIBA 02/2008 - 11/2007
1	4- (3- fluoro- 2- methylphenyl)- 4,5- dihydrooxazol- 2- ylamineIBA 01/2024
1	RO5166017IBA 01/2024
1	Olanzapine (Zyprexa)FDA Link 01/2024
1	CorticosteroneIBA 01/2024
1	Glutamic Acid (Glutamate)FDA Link 12/2023
1	Risperidone (Risperdal Consta)FDA LinkGeneric 12/2022
1	ProlactinIBA 12/2021
1	CholesterolIBA 12/2021
1	Capsules (Microcapsules)IBA 10/2021
1	TabletsIBA 10/2021
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2021
1	Antidepressive Agents (Antidepressants)IBA 01/2021
1	Chlorpromazine (Thorazine)FDA Link 10/2019
1	Phencyclidine (Angel Dust)IBA 10/2019
1	3,4-dihydroxyphenylglycolIBA 02/2016
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 02/2016
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 08/2013
1	Orexin Receptor AntagonistsIBA 01/2010
1	Tryptamines (Triptans)IBA 11/2009
1	Sumatriptan (Imigran)FDA LinkGeneric 11/2009
1	OrexinsIBA 07/2009
1	2- (4- cyclopropylphenyl)- N- (1- (5- ((2,2,2- trifluoroethyl)oxo)pyridin- 2- yl)ethyl)acetamideIBA 06/2009
1	triphenylphosphine oxideIBA 01/2009
1	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 01/2009
1	compound 30IBA 10/2008
1	telcagepantIBA 02/2008
1	NeuropeptidesIBA 02/2008
1	Amyloid beta-PeptidesIBA 11/2006
1	Proteins (Proteins, Gene)FDA Link 11/2006
1	Peptides (Polypeptides)IBA 11/2006
1	Amyloid (Amyloid Fibrils)IBA 11/2006
1	BenzodiazepinesIBA 10/2006
1	PiperidinesIBA 10/2006

Therapy/Procedure

3	Therapeutics 01/2022 - 02/2008
2	Ligation 07/2011 - 08/2002
1	Glycemic Control 01/2024
1	Oral Administration 07/2011