Joel E Kleinman Selected Research

metabotropic glutamate receptor 3 (mGluR3)

12/2020	Association of Missense Mutation in FOLH1 With Decreased NAAG Levels and Impaired Working Memory Circuitry and Cognition.
11/2016	Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study.
11/2008	Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia.
10/2008	Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP.

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Joel E Kleinman Research Topics

Disease

76	Schizophrenia (Dementia Praecox) 04/2024 - 05/2002
8	Mental Disorders (Mental Disorder) 09/2022 - 12/2002
8	Bipolar Disorder (Manic Depressive Psychosis) 01/2017 - 10/2004
6	Major Depressive Disorder (Major Depressive Disorders) 09/2022 - 12/2004
5	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 01/2011
5	Mood Disorders (Mood Disorder) 01/2020 - 05/2002
4	Psychotic Disorders (Schizoaffective Disorder) 01/2020 - 03/2003
3	Neurodevelopmental Disorders 01/2015 - 09/2003
3	Substance-Related Disorders (Drug Abuse) 03/2008 - 12/2006
2	Genetic Risk Score 04/2024 - 09/2023
2	Parkinson Disease (Parkinson's Disease) 11/2023 - 04/2010
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 10/2023 - 01/2022
2	Autistic Disorder (Autism) 01/2022 - 08/2010
2	Cognitive Dysfunction 06/2014 - 08/2010
2	Classical Lissencephalies and Subcortical Band Heterotopias 04/2006 - 01/2006
2	Fasciculation (Fasciculations) 04/2006 - 01/2006
1	Neoplasms (Cancer) 01/2024
1	Tobacco Use Disorder (Nicotine Dependence) 01/2023
1	Proteostasis Deficiencies 09/2022
1	Disease Progression 07/2022
1	Opioid-Related Disorders (Opiate Addiction) 01/2021
1	Opiate Overdose 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Necrosis 10/2016
1	Pitt-Hopkins syndrome 04/2016
1	Weight Gain 11/2015
1	Obesity 11/2015
1	Dementia (Dementias) 09/2015
1	Central Nervous System Diseases (CNS Diseases) 03/2013
1	Inflammation (Inflammations) 01/2013
1	Neuroinflammatory Diseases 01/2013

Drug/Important Bio-Agent (IBA)

32	Messenger RNA (mRNA)IBA 12/2020 - 08/2003
18	Proteins (Proteins, Gene)FDA Link 09/2022 - 06/2004
14	RNA (Ribonucleic Acid)IBA 02/2024 - 12/2004
13	Protein Isoforms (Isoforms)IBA 11/2022 - 04/2006
7	Dopamine (Intropin)FDA LinkGeneric 04/2024 - 03/2003
5	Neuregulin-1 (Neuregulin 1)IBA 09/2014 - 04/2006
4	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2013
4	Antipsychotic Agents (Antipsychotics)IBA 11/2022 - 03/2008
4	Glutamic Acid (Glutamate)FDA Link 12/2020 - 01/2004
4	metabotropic glutamate receptor 3 (mGluR3)IBA 12/2020 - 10/2008
3	Transcription Factors (Transcription Factor)IBA 01/2022 - 01/2008
3	MicroRNAs (MicroRNA)IBA 09/2019 - 01/2019
3	NeuregulinsIBA 01/2017 - 08/2010
3	gamma-Aminobutyric Acid (GABA)IBA 01/2016 - 07/2011
3	DNA (Deoxyribonucleic Acid)IBA 10/2012 - 09/2008
3	EnzymesIBA 01/2011 - 06/2004
3	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 11/2008 - 01/2004
3	Estrogen Receptor alphaIBA 08/2008 - 12/2004
2	GlucocorticoidsIBA 10/2023 - 12/2004
2	Opioid Analgesics (Opioids)IBA 01/2021 - 03/2008
2	Olanzapine (Zyprexa)FDA Link 01/2019 - 09/2013
2	Nerve Growth Factors (Neurotrophins)IBA 01/2017 - 09/2014
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 11/2015 - 12/2002
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 09/2015 - 10/2004
2	Apolipoprotein E4IBA 09/2015 - 01/2015
2	Cocaine (Cocaine HCl)IBA 03/2008 - 12/2006
2	DysbindinIBA 01/2008 - 06/2004
2	ElementsIBA 04/2006 - 01/2006
2	neurabinIBA 10/2004 - 06/2004
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2004 - 09/2003
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2024
1	Epidermal Growth Factor (EGF)IBA 01/2024
1	Protein Kinases (Protein Kinase)IBA 01/2024
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2024
1	Bone Morphogenetic Protein 4IBA 01/2024
1	Apolipoproteins E (ApoE)IBA 10/2023
1	Galantamine (Galanthamine)FDA LinkGeneric 01/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023
1	Dextromethorphan (Racemethorphan)FDA LinkGeneric 01/2023
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 11/2022
1	Indicators and Reagents (Reagents)IBA 09/2022
1	hydrogen sulfite (bisulfite)IBA 01/2021
1	ArsenicIBA 01/2021
1	MethyltransferasesIBA 01/2021
1	Netrin-1IBA 01/2021
1	Sorting NexinsIBA 01/2020
1	Ethanol (Ethyl Alcohol)IBA 01/2020
1	Dronabinol (THC)FDA LinkGeneric 01/2020
1	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2020
1	EndocannabinoidsIBA 01/2020
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 11/2016
1	AntibodiesIBA 11/2016
1	InterferonsIBA 10/2016
1	CytokinesIBA 10/2016
1	Transcription Factor 4IBA 04/2016
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2016
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2016
1	arsenite methyltransferaseIBA 01/2016
1	Nicotine FDA Link 01/2016
1	Amyloid beta-PeptidesIBA 09/2015
1	ChromatinIBA 01/2015
1	Sodium Channels (Sodium Channel)IBA 06/2014
1	Member 2 Solute Carrier Family 12IBA 04/2014
1	CationsIBA 04/2014
1	CateninsIBA 08/2013
1	Serotonin (5 Hydroxytryptamine)IBA 03/2013
1	CannabinoidsIBA 11/2012

Therapy/Procedure

2	Therapeutics 07/2022 - 09/2009