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Fumitaka Kikkawa Selected Research

Small Interfering RNA (siRNA)

5/2020Pegylated Liposomal Doxorubicin/Oxaliplatin Chemotherapy Can Overcome Cisplatin Resistance in Spectrin αII-Overexpressing Ovarian Carcinoma.
8/2018Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells.
1/2013Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.
1/2012Spectrin αII and βII tetramers contribute to platinum anticancer drug resistance in ovarian serous adenocarcinoma.
11/2010Growth-suppressing function of glypican-3 (GPC3) via insulin like growth factor II (IGF-II) signaling pathway in ovarian clear cell carcinoma cells.
1/2010Gene silencing of glypican-3 in clear cell carcinoma of the ovary renders it more sensitive to the apoptotic agent paclitaxel in vitro and in vivo.
2/2009N-acetylglucosaminyltransferase V regulates extravillous trophoblast invasion through glycosylation of alpha5beta1 integrin.
1/2007Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma.

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Fumitaka Kikkawa Research Topics

Disease

115Neoplasms (Cancer)
01/2022 - 01/2003
51Carcinoma (Carcinomatosis)
03/2022 - 01/2002
36Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 01/2002
20Ovarian Epithelial Carcinoma
12/2020 - 04/2003
19Uterine Cervical Neoplasms (Cancer of the Cervix)
10/2021 - 03/2008
18Endometriosis
01/2023 - 01/2006
16Choriocarcinoma
07/2021 - 01/2002
16Neoplasm Metastasis (Metastasis)
12/2020 - 07/2004
14Endometrial Neoplasms (Endometrial Cancer)
01/2018 - 08/2003
9Adenocarcinoma
06/2016 - 01/2003
8Hydatidiform Mole (Molar Pregnancy)
06/2020 - 01/2007
7Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)
06/2020 - 04/2013
7Rupture
03/2019 - 01/2009
7Endometrioid Carcinoma
01/2014 - 03/2003
6Congenital Diaphragmatic Hernias
01/2021 - 07/2007
6Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2020 - 05/2004
6Teratoma (Teratoid Tumor)
12/2019 - 05/2012
5Glioblastoma (Glioblastoma Multiforme)
01/2021 - 01/2016
5Ascites
12/2019 - 11/2007
5Infections
01/2019 - 04/2008
5Residual Neoplasm
05/2016 - 10/2011
4Infertility (Sterility)
07/2021 - 09/2008
4Lymphatic Metastasis
05/2019 - 01/2005
4Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
04/2019 - 07/2010
4Mucinous Adenocarcinoma (Mucinous Carcinoma)
03/2019 - 10/2006
4Inflammation (Inflammations)
05/2018 - 11/2015
3Melanoma (Melanoma, Malignant)
12/2020 - 02/2010
3Cicatrix (Scar)
02/2020 - 01/2006
3Lung Neoplasms (Lung Cancer)
01/2020 - 04/2010
3Hemorrhage
08/2019 - 06/2015
3Nausea
01/2019 - 01/2016
3Vomiting
01/2019 - 01/2016
3Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
10/2018 - 05/2012
3Hypoxia (Hypoxemia)
07/2018 - 01/2008
3Placenta Previa
06/2015 - 10/2007

Drug/Important Bio-Agent (IBA)

19Paclitaxel (Taxol)FDA LinkGeneric
01/2020 - 10/2003
17Proteins (Proteins, Gene)FDA Link
11/2021 - 04/2003
12PlatinumIBA
03/2022 - 11/2004
12Cisplatin (Platino)FDA LinkGeneric
01/2021 - 01/2002
11EnzymesIBA
02/2018 - 04/2003
11Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
02/2010 - 05/2002
11Complementary DNA (cDNA)IBA
11/2009 - 04/2003
10Peptides (Polypeptides)IBA
10/2021 - 03/2003
10Hormones (Hormone)IBA
01/2021 - 02/2009
10Carboplatin (JM8)FDA LinkGeneric
05/2020 - 11/2004
10Plasma GasesIBA
01/2020 - 06/2016
9ParaffinIBA
01/2020 - 01/2004
9leucyl-cystinyl aminopeptidaseIBA
04/2007 - 01/2002
8Indicators and Reagents (Reagents)IBA
01/2021 - 04/2008
8Small Interfering RNA (siRNA)IBA
05/2020 - 01/2007
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2018 - 12/2003
8Angiotensin IIIBA
05/2011 - 08/2003
7Biomarkers (Surrogate Marker)IBA
02/2021 - 03/2014
7Formaldehyde (Formol)FDA Link
01/2020 - 01/2004
7GlypicansIBA
09/2014 - 01/2010
6Cadherins (E-Cadherin)IBA
01/2020 - 05/2003
5MicroRNAs (MicroRNA)IBA
02/2021 - 08/2014
5Capsules (Microcapsules)IBA
03/2019 - 12/2011
5Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 05/2016
5HydrogenIBA
05/2018 - 04/2014
5Messenger RNA (mRNA)IBA
03/2018 - 01/2008
4taxaneIBA
03/2022 - 10/2011
4HLA Antigens (Human Leukocyte Antigens)IBA
10/2021 - 04/2006
4Ringer's LactateIBA
03/2021 - 11/2016
4SolutionsIBA
03/2021 - 11/2016
4ChemokinesIBA
01/2020 - 01/2007
4CytokinesIBA
01/2020 - 02/2003
4LipopolysaccharidesIBA
05/2018 - 11/2015
4Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
06/2010 - 04/2008
4Glutamyl Aminopeptidase (Aspartyl Aminopeptidase)IBA
04/2005 - 08/2003
4Neprilysin (Neutral Endopeptidase)IBA
03/2005 - 04/2003
4Oxytocin (Pitocin)FDA LinkGeneric
08/2004 - 04/2003
3Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
07/2021 - 05/2009
3DNA (Deoxyribonucleic Acid)IBA
07/2021 - 01/2007
3Protein Subunit VaccinesIBA
02/2021 - 01/2014
3IronIBA
10/2020 - 12/2015
3SpectrinIBA
05/2020 - 01/2012
3Transcription Factors (Transcription Factor)IBA
01/2020 - 04/2010
3IntegrinsIBA
01/2020 - 10/2009
3Luteinizing Hormone (Lutropin)FDA LinkGeneric
04/2019 - 01/2016
3ProgesteroneFDA LinkGeneric
01/2019 - 12/2012
3Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2017 - 06/2009
3AntigensIBA
09/2014 - 06/2012
3Conditioned Culture MediaIBA
11/2012 - 01/2005
3Glucose (Dextrose)FDA LinkGeneric
10/2010 - 06/2006
3Insulin (Novolin)FDA Link
07/2010 - 03/2004
3paclitaxel 2'-ethylcarbonateIBA
02/2010 - 03/2007

Therapy/Procedure

40Drug Therapy (Chemotherapy)
03/2022 - 01/2002
26Therapeutics
03/2021 - 10/2003
12Hysterectomy
05/2020 - 05/2004
8Lymph Node Excision (Lymph Node Dissection)
01/2021 - 06/2008
8Cystectomy
10/2019 - 04/2011
7Cesarean Section (Caesarean Section)
08/2019 - 01/2006
7Radiotherapy
08/2019 - 03/2008
4Adjuvant Chemotherapy
03/2022 - 12/2011
4Cytoreduction Surgical Procedures
01/2019 - 01/2006
4Chemoradiotherapy
01/2017 - 01/2015
3Neoadjuvant Therapy
01/2022 - 01/2004
3Immunotherapy
10/2021 - 09/2011
3Salpingo-oophorectomy
01/2020 - 01/2006