L Jaap Kappelle Selected Research

Heart Failure

5/2024	Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients.
1/2018	Decline in risk of recurrent cardiovascular events in the period 1996 to 2014 partly explained by better treatment of risk factors and less subclinical atherosclerosis.
1/2018	Estimated Life Expectancy Without Recurrent Cardiovascular Events in Patients With Vascular Disease: The SMART-REACH Model.

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L Jaap Kappelle Research Topics

Disease

69	Stroke (Strokes) 05/2024 - 10/2002
44	Ischemic Stroke 05/2024 - 10/2002
18	Infarction (Infarctions) 01/2021 - 02/2003
10	Hemorrhage 01/2022 - 12/2011
10	Carotid Stenosis (Carotid Artery Stenosis) 01/2019 - 09/2003
9	Vascular Diseases (Vascular Disease) 07/2021 - 10/2009
8	Brain Ischemia (Cerebral Ischemia) 01/2019 - 10/2002
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 01/2016
6	Thrombosis (Thrombus) 01/2023 - 01/2010
6	Transient Ischemic Attack 10/2021 - 06/2003
6	Hypertension (High Blood Pressure) 07/2021 - 05/2009
6	Myocardial Infarction 07/2021 - 06/2006
6	Pathologic Constriction (Stenosis) 01/2019 - 08/2002
5	Type 2 Diabetes Mellitus (MODY) 10/2021 - 04/2004
4	Cognitive Dysfunction 01/2024 - 06/2003
4	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2023 - 01/2018
4	Atrial Fibrillation 01/2023 - 01/2012
4	Edema (Dropsy) 12/2019 - 02/2003
4	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/2016 - 04/2006
3	Heart Failure 05/2024 - 01/2018
3	Dementia (Dementias) 05/2024 - 07/2013
3	Hypotension (Low Blood Pressure) 01/2020 - 12/2011
3	Cerebral Hemorrhage 01/2020 - 12/2011
3	Atrophy 01/2014 - 05/2008
3	Cerebral Infarction 09/2013 - 04/2009
3	Fever (Fevers) 05/2009 - 02/2003
2	Cerebral Small Vessel Diseases 01/2022 - 06/2020
2	Coronary Disease (Coronary Heart Disease) 01/2019 - 06/2006
2	Aneurysm (Aneurysms) 01/2018 - 01/2016
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2016 - 01/2006
2	Peripheral Arterial Disease 01/2016 - 01/2015
1	Orthostatic Hypotension (Postural Hypotension) 05/2024
1	Brain Injuries (Brain Injury) 05/2024
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2023
1	Chronic Kidney Failure (Chronic Renal Failure) 10/2021
1	Ischemia 10/2021
1	Migraine Disorders (Migraine) 12/2019
1	Clinical Deterioration 01/2019
1	Rupture 01/2018
1	Sudden Death 01/2018
1	Diabetes Mellitus 01/2018

Drug/Important Bio-Agent (IBA)

12	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 01/2006
9	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 10/2021 - 01/2006
9	Cytidine Triphosphate (CTP)IBA 12/2020 - 02/2014
8	AnticoagulantsIBA 01/2023 - 12/2011
8	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2017 - 02/2003
8	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 06/2006
6	Clopidogrel (Plavix)FDA Link 10/2021 - 01/2014
6	Retinaldehyde (Retinal)IBA 01/2018 - 02/2003
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2019
5	EsapentIBA 10/2021 - 06/2006
5	Dipyridamole (Persantine)FDA LinkGeneric 10/2021 - 01/2006
5	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2018 - 01/2010
4	Proteins (Proteins, Gene)FDA Link 12/2023 - 10/2013
4	ORALIT (ORS)IBA 01/2022 - 07/2013
4	omega-Chloroacetophenone (Mace)IBA 07/2021 - 01/2016
3	Antihypertensive Agents (Antihypertensives)IBA 05/2024 - 01/2016
3	Vitamin K FDA Link 01/2023 - 01/2012
3	CholesterolIBA 01/2018 - 10/2015
3	LipidsIBA 11/2016 - 10/2009
2	Amyloid (Amyloid Fibrils)IBA 01/2023 - 01/2016
2	CreatinineIBA 10/2021 - 01/2018
2	HDL CholesterolIBA 10/2021 - 01/2016
2	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 03/2016 - 12/2011
2	Warfarin (Coumadin)FDA LinkGeneric 09/2015 - 09/2012
2	apixabanIBA 09/2015 - 01/2012
2	Contrast MediaIBA 06/2015 - 09/2003
2	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 01/2011
2	alpha-2-Antiplasmin (alpha 2 Antiplasmin)IBA 01/2014 - 10/2013
2	Cystatin CIBA 01/2014 - 10/2013
2	Oxygen (Dioxygen)IBA 01/2014 - 10/2002
1	hydroxide ionIBA 05/2024
1	Blood Proteins (Serum Proteins)IBA 12/2023
1	IodineIBA 01/2023
1	PrionsIBA 01/2023
1	AlbuminsIBA 10/2021
1	Sodium-Glucose Transport ProteinsIBA 01/2021
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2021
1	Proprotein Convertase 9IBA 01/2018
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2018
1	AndrogensIBA 01/2017

Therapy/Procedure

19	Therapeutics 01/2023 - 08/2005
12	Carotid Endarterectomy 01/2022 - 08/2002
8	Endarterectomy (Thromboendarterectomy) 01/2019 - 10/2002
5	Thrombectomy 05/2024 - 01/2010
5	Secondary Prevention 01/2023 - 01/2006
5	Surgical Decompression 01/2021 - 04/2009
5	Stents 01/2019 - 01/2014
4	Conservative Treatment 01/2022 - 09/2006
3	Aftercare (After-Treatment) 01/2019 - 09/2008
2	Time-to-Treatment 10/2016 - 08/2009
2	Activities of Daily Living (ADL) 01/2016 - 04/2006
2	Contraindications 12/2011 - 01/2010
1	Neurosurgical Procedures 01/2023
1	Length of Stay 01/2023
1	Punctures 01/2023
1	Endovascular Procedures 01/2022
1	Resuscitation Orders (Do Not Resuscitate Orders) 01/2020
1	Patient Admission (Patient Admissions) 01/2018
1	Orchiectomy (Orchidectomy) 01/2017