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William Janssen Selected Research

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)

11/2017Consolidation Therapy for Newly Diagnosed Pediatric Patients with High-Risk Neuroblastoma Using Busulfan/Melphalan, Autologous Hematopoietic Cell Transplantation, Anti-GD2 Antibody, Granulocyte-Macrophage Colony-Stimulating Factor, Interleukin-2, and Haploidentical Natural Killer Cells.
2/2007A phase-I trial using a universal GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) in the formulation of autologous tumor cell-based vaccines for cancer patients with stage IV disease.

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William Janssen Research Topics

Disease

6Neoplasms (Cancer)
04/2012 - 05/2002
3Graft vs Host Disease (Graft-Versus-Host Disease)
09/2013 - 07/2010
2Fibrosis (Cirrhosis)
01/2018 - 04/2014
2Pneumonia (Pneumonitis)
01/2018 - 01/2013
2Lung Diseases (Lung Disease)
01/2018 - 04/2014
2Melanoma (Melanoma, Malignant)
10/2012 - 02/2007
2Renal Cell Carcinoma (Grawitz Tumor)
01/2008 - 05/2002
2Disease Progression
01/2008 - 02/2007
1Parkinson Disease (Parkinson's Disease)
01/2022
1Diabetic Nephropathies (Diabetic Nephropathy)
10/2020
1Mitochondrial Diseases (Mitochondrial Disease)
01/2020
1Hypertension (High Blood Pressure)
01/2019
1X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
01/2019
1Hematologic Neoplasms (Hematological Malignancy)
02/2018
1Residual Neoplasm
11/2017
1Neuroblastoma
11/2017
1Idiopathic Pulmonary Fibrosis
04/2014
1Pulmonary Fibrosis (Fibrosing Alveolitis)
04/2014
1Lung Injury
01/2013
1Acute Lung Injury
01/2013
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2013
1Body Weight (Weight, Body)
04/2012
1Glucose Intolerance
04/2012
1Prostatic Neoplasms (Prostate Cancer)
04/2012
1Sarcoma (Soft Tissue Sarcoma)
02/2012
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2011
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
03/2011
1Hypoalbuminemia
03/2011
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
03/2011
1Mucositis
07/2010
1Pathologic Complete Response
01/2008
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
02/2007
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
02/2006

Drug/Important Bio-Agent (IBA)

4Interleukin-2 (IL2)IBA
11/2017 - 05/2002
3CytokinesIBA
01/2018 - 01/2013
3VaccinesIBA
01/2008 - 05/2002
2Proteins (Proteins, Gene)FDA Link
10/2020 - 04/2012
2Busulfan (Busulfex)FDA Link
11/2017 - 10/2011
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
11/2017 - 02/2007
2Peptides (Polypeptides)IBA
04/2012 - 05/2002
2Methotrexate (Mexate)FDA LinkGeneric
10/2011 - 07/2010
2Tacrolimus (Prograf)FDA LinkGeneric
10/2011 - 07/2010
2Mycophenolic Acid (Cellcept)FDA LinkGeneric
10/2011 - 07/2010
1Glucosylceramidase (Glucocerebrosidase)IBA
01/2022
1Superoxides (Superoxide)IBA
01/2020
1Dasatinib (BMS 354825)FDA Link
01/2019
1Interleukin-13IBA
01/2018
1Melphalan (Alkeran)FDA LinkGeneric
11/2017
1Hydroxyproline (4 Hydroxyproline)IBA
04/2014
1CollagenIBA
04/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2014
1indium-bleomycinIBA
04/2014
1Minor Histocompatibility AntigensIBA
09/2013
1EndotoxinsIBA
01/2013
1Interleukin-6 (Interleukin 6)IBA
01/2013
1Biomarkers (Surrogate Marker)IBA
01/2013
1CorticosteroneIBA
04/2012
1EnzymesIBA
04/2012
1AndrogensIBA
04/2012
1ImmunosorbentsIBA
04/2012
1fludarabineIBA
10/2011
1Sirolimus (Rapamycin)FDA Link
10/2011
1Serum AlbuminIBA
03/2011
1Narcotics (Narcotic Analgesics)IBA
07/2010
1CD40 Ligand (CD40L)IBA
02/2007
1Cancer VaccinesIBA
02/2006
1Neoplasm Antigens (Tumor Antigens)IBA
05/2002

Therapy/Procedure

3Drug Therapy (Chemotherapy)
01/2019 - 02/2006
3Injections
04/2012 - 02/2007
2Hematopoietic Stem Cell Transplantation
01/2019 - 03/2011
2Transplantation
02/2018 - 09/2013
2Immunotherapy
11/2017 - 02/2006
2Therapeutics
11/2017 - 02/2012
2Cell Transplantation
11/2017 - 10/2011
2Radiotherapy
04/2012 - 02/2012
1Artificial Respiration (Mechanical Ventilation)
01/2013
1Homologous Transplantation
10/2011
1Analgesia
07/2010
1Parenteral Nutrition
07/2010