Connie Jackaman Selected Research

Cytokines

1/2019	CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy.
1/2018	Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.
6/2016	Murine mesothelioma induces locally-proliferating IL-10(+)TNF-α(+)CD206(-)CX3CR1(+) M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy.
7/2005	Intratumoral poly-N-acetyl glucosamine-based polymer matrix provokes a prolonged local inflammatory response that, when combined with IL-2, induces regression of malignant mesothelioma in a murine model.

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Connie Jackaman Research Topics

Disease

17	Neoplasms (Cancer) 01/2022 - 11/2003
10	Mesothelioma 01/2022 - 11/2003
3	Inflammation (Inflammations) 01/2022 - 07/2005
2	Infections 01/2019 - 01/2014
2	Cachexia 01/2019 - 01/2018
1	Liver Diseases (Liver Disease) 05/2023
1	Encephalitis (Encephalitis, Rasmussen) 10/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2022
1	Body Weight (Weight, Body) 01/2018
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2018
1	Necrosis 01/2018
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2018
1	Lewis Lung Carcinoma 08/2006
1	Malignant Mesothelioma 07/2005

Drug/Important Bio-Agent (IBA)

6	Interleukin-2 (IL2)IBA 06/2012 - 11/2003
5	Neoplasm Antigens (Tumor Antigens)IBA 01/2019 - 08/2006
5	AntigensIBA 01/2019 - 07/2005
4	CytokinesIBA 01/2019 - 07/2005
3	OvalbuminIBA 01/2019 - 08/2006
3	EpitopesIBA 01/2019 - 08/2006
2	Interleukin-12 (IL 12)IBA 01/2018 - 07/2005
2	LipidsIBA 01/2015 - 01/2014
2	Cisplatin (Platino)FDA LinkGeneric 01/2013 - 12/2012
1	Small Nuclear RNA (snRNA)IBA 05/2023
1	Proteins (Proteins, Gene)FDA Link 10/2022
1	ApoferritinsIBA 10/2022
1	Ferritins (Ferritin)IBA 10/2022
1	IronIBA 10/2022
1	MetalsIBA 10/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 10/2022
1	Protein AggregatesIBA 10/2022
1	Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA 01/2022
1	Macrophage Colony-Stimulating FactorIBA 01/2022
1	AntioxidantsIBA 01/2022
1	PerforinIBA 01/2018
1	Stavudine (Zerit)FDA LinkGeneric 01/2018
1	Conditioned Culture MediaIBA 06/2016
1	Gemcitabine FDA Link 06/2016
1	Lipoproteins (Lipoprotein)IBA 01/2015
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2015
1	Triglycerides (Triacylglycerol)IBA 01/2015
1	Chelating AgentsIBA 01/2013
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2013
1	Penicillamine (Cuprimine)FDA Link 01/2013
1	tetrathiomolybdate (ammonium tetrathiomolybdate)IBA 01/2013
1	Trientine (Trien)FDA Link 01/2013
1	CopperIBA 01/2013
1	Histocompatibility Antigens Class IIBA 12/2012
1	Therapeutic UsesIBA 06/2012
1	AutoantigensIBA 02/2011
1	Immunoglobulins (Immunoglobulin)IBA 02/2011
1	VaccinesIBA 11/2008
1	poly-N-acetyl glucosamineIBA 07/2005
1	PolymersIBA 07/2005
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 07/2005

Therapy/Procedure

8	Immunotherapy 01/2018 - 11/2003
6	Therapeutics 01/2022 - 11/2003
5	Drug Therapy (Chemotherapy) 01/2019 - 11/2008
1	Withholding Treatment 06/2016
1	Rejuvenation 06/2014