Darrell J Irvine Selected Research

Disease Progression

1/2020	Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.
1/2019	Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid.

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Darrell J Irvine Research Topics

Disease

80	Neoplasms (Cancer) 04/2024 - 04/2008
15	Melanoma (Melanoma, Malignant) 01/2024 - 12/2009
11	Infections 01/2020 - 09/2008
7	Bites and Stings (Sting) 01/2023 - 06/2015
5	Communicable Diseases (Infectious Diseases) 02/2023 - 09/2008
5	Inflammation (Inflammations) 01/2023 - 10/2016
4	Anthrax 04/2024 - 02/2021
4	Human Influenza (Influenza) 11/2022 - 03/2011
3	Hematologic Neoplasms (Hematological Malignancy) 12/2023 - 12/2019
3	COVID-19 01/2023 - 01/2021
3	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2019
3	Malaria 08/2014 - 01/2012
2	Breast Neoplasms (Breast Cancer) 01/2022 - 03/2021
2	Virus Diseases (Viral Diseases) 01/2022 - 01/2014
2	Skin Neoplasms (Skin Cancer) 01/2021 - 01/2020
2	Disease Progression 01/2020 - 01/2019
2	Lymphoma (Lymphomas) 11/2018 - 06/2015
2	Wiskott-Aldrich Syndrome 10/2016 - 03/2015
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2024
1	Leukemia 04/2024
1	Wounds and Injuries (Trauma) 01/2024
1	Neuroblastoma 12/2023
1	Ovarian Neoplasms (Ovarian Cancer) 03/2023
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023
1	Male Infertility (Male Sterility) 01/2023
1	Glioma (Gliomas) 01/2023
1	Glioblastoma (Glioblastoma Multiforme) 01/2023
1	Lung Neoplasms (Lung Cancer) 01/2023
1	Carcinoma (Carcinomatosis) 01/2022

Drug/Important Bio-Agent (IBA)

28	AntigensIBA 01/2024 - 09/2008
24	VaccinesIBA 04/2024 - 09/2008
19	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2006
17	CytokinesIBA 01/2024 - 12/2009
9	InterferonsIBA 01/2023 - 12/2016
9	Interleukin-2 (IL2)IBA 01/2023 - 04/2015
8	Neoplasm Antigens (Tumor Antigens)IBA 01/2024 - 03/2013
8	Immune Checkpoint InhibitorsIBA 01/2023 - 11/2017
8	AntibodiesIBA 01/2022 - 08/2011
7	LigandsIBA 01/2024 - 12/2009
7	Liposomes (Liposome)IBA 01/2023 - 08/2011
6	Chimeric Antigen ReceptorsIBA 04/2024 - 01/2018
6	Peptides (Polypeptides)IBA 01/2024 - 01/2017
4	LipidsIBA 01/2022 - 01/2012
4	Granzymes (Granzyme)IBA 01/2022 - 01/2017
4	Protein Subunit VaccinesIBA 01/2022 - 01/2021
3	EpitopesIBA 04/2024 - 01/2022
3	Polysaccharides (Glycans)IBA 01/2024 - 12/2009
3	Cancer VaccinesIBA 01/2024 - 01/2019
3	Interleukin-12 (IL 12)IBA 03/2023 - 01/2020
3	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2019
3	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2022 - 01/2020
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021 - 12/2009
3	HydrogelsIBA 06/2020 - 09/2008
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 03/2019 - 08/2012
3	Interleukin-15 (Interleukin 15)IBA 01/2018 - 12/2009
3	Immunologic Factors (Immunomodulators)IBA 01/2017 - 12/2013
3	NanocapsulesIBA 06/2015 - 08/2014
2	Messenger RNA (mRNA)IBA 01/2024 - 01/2023
2	Anaplastic Lymphoma KinaseIBA 12/2023 - 01/2023
2	Immunologic Adjuvants (Immunologic Adjuvant)IBA 01/2023 - 01/2019
2	Lipid NanoparticlesIBA 01/2023 - 08/2011
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 10/2021
2	resiquimodIBA 01/2023 - 06/2020
2	Glycoproteins (Glycoprotein)IBA 01/2022 - 01/2021
2	aluminum sulfate (alum)IBA 01/2022 - 01/2022
2	Mitoxantrone (Novantrone)FDA LinkGeneric 10/2021 - 12/2017
2	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2014
2	Immunomodulating AgentsIBA 01/2021 - 08/2015
2	Monoclonal AntibodiesIBA 01/2021 - 01/2019
2	Vaccine AdjuvantsIBA 01/2021 - 06/2015
2	GoldIBA 01/2019 - 09/2014
2	InterleukinsIBA 01/2018 - 12/2013
2	AlbuminsIBA 11/2017 - 03/2014
2	Biocompatible Materials (Biomaterials)IBA 01/2017 - 08/2010
2	Chemotactic FactorsIBA 03/2013 - 07/2011
2	NanovaccinesIBA 01/2012 - 01/2012
1	ChemokinesIBA 01/2024
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2024
1	LectinsIBA 01/2024
1	Synthetic Vaccines (Recombinant Vaccines)IBA 09/2023
1	Single-Chain AntibodiesIBA 09/2023
1	Protons (Proton)IBA 01/2023
1	ProdrugsIBA 01/2023
1	Tyrosine Kinase InhibitorsIBA 01/2023
1	InflammasomesIBA 01/2023
1	Toll-Like Receptor 7IBA 01/2023
1	Recombinases (Recombinase)IBA 01/2023
1	Programmed Cell Death 1 ReceptorIBA 01/2023
1	Complement System Proteins (Complement)IBA 11/2022
1	Aluminum Hydroxide (Algeldrate)FDA Link 01/2022
1	Carrier Proteins (Binding Protein)IBA 01/2022
1	MannansIBA 01/2022

Therapy/Procedure

41	Immunotherapy 01/2024 - 04/2008
34	Therapeutics 01/2024 - 12/2009
4	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2018 - 10/2013
3	Radiotherapy 11/2017 - 09/2014
3	Drug Therapy (Chemotherapy) 01/2017 - 12/2013
2	Injections 06/2020 - 12/2009
1	Intravenous Administration 01/2023
1	Neoadjuvant Therapy 01/2022