Matthew D Hirschey Selected Research

Doxycycline (Periostat)

9/2022

In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence.

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Matthew D Hirschey Research Topics

Disease

13	Neoplasms (Cancer) 04/2024 - 01/2013
7	Insulin Resistance 10/2020 - 08/2011
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2012
4	Fatty Liver 12/2019 - 10/2011
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 08/2011
3	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 09/2015
3	Breast Neoplasms (Breast Cancer) 09/2022 - 01/2020
3	Alcoholic Liver Diseases (Alcoholic Liver Disease) 12/2019 - 03/2012
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2015 - 10/2011
3	Obesity 02/2013 - 10/2011
2	Triple Negative Breast Neoplasms 04/2024 - 01/2021
2	Inflammation (Inflammations) 01/2023 - 12/2019
2	Glucose Intolerance 10/2020 - 04/2017
2	Carcinogenesis 01/2019 - 11/2014
2	Overnutrition 01/2018 - 05/2013
2	Friedreich Ataxia (Friedreich's Ataxia) 07/2017 - 01/2017
2	Cardiomyopathies (Cardiomyopathy) 07/2017 - 01/2017
2	Heart Failure 01/2017 - 01/2014
1	Bites and Stings (Sting) 01/2023
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2023
1	Albuminuria 01/2023
1	Parkinson Disease (Parkinson's Disease) 01/2021
1	Liver Neoplasms (Liver Cancer) 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Dyslipidemias (Dyslipidemia) 01/2018
1	Hypertrophy 12/2017
1	Starvation 10/2017
1	Liver Diseases (Liver Disease) 10/2017
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2017
1	Cardiomegaly (Heart Hypertrophy) 01/2017
1	Heart Diseases (Heart Disease) 01/2017
1	Human Influenza (Influenza) 09/2015
1	Infections 09/2015
1	Lung Injury 09/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2015
1	Glutaric Acidemia I 04/2014
1	Metabolic Diseases (Metabolic Disease) 02/2013
1	Hyperlipidemias (Hyperlipidemia) 10/2011

Drug/Important Bio-Agent (IBA)

9	Sirtuin 3IBA 01/2023 - 08/2011
7	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 05/2013
6	SirtuinsIBA 01/2018 - 01/2013
6	Proteins (Proteins, Gene)FDA Link 12/2017 - 01/2013
5	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2017 - 10/2011
4	Fatty Acids (Saturated Fatty Acids)IBA 09/2022 - 01/2014
4	Ethanol (Ethyl Alcohol)IBA 12/2019 - 03/2012
3	NAD (NADH)IBA 01/2023 - 01/2013
3	Leucine (L-Leucine)FDA Link 10/2020 - 04/2017
3	EnzymesIBA 01/2019 - 10/2011
2	LipidsIBA 09/2022 - 01/2021
2	Nicotinamide MononucleotideIBA 12/2019 - 07/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 04/2024
1	nicotinamide-beta-ribosideIBA 01/2023
1	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2023
1	Mitochondrial DNA (mtDNA)IBA 01/2023
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2023
1	Adenine NucleotidesIBA 01/2023
1	InterferonsIBA 01/2023
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2022
1	etomoxirIBA 09/2022
1	Doxycycline (Periostat)FDA LinkGeneric 09/2022
1	Perphenazine (Trilafon)FDA LinkGeneric 01/2021
1	4,4- difluoro- 5,7- dimethyl- 4- bora- 3a,4a- diaza- s- indacene- 3- hexadecanoic acidIBA 01/2021
1	PalmitatesIBA 01/2021
1	RotenoneIBA 01/2021
1	AntioxidantsIBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 12/2019
1	Branched-Chain Amino AcidsIBA 01/2019
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2019
1	Insulin (Novolin)FDA Link 01/2018
1	FructoseIBA 01/2018
1	CarbonIBA 10/2017
1	TrehaloseIBA 10/2017
1	Malonyl Coenzyme A (Malonyl CoA)IBA 01/2017
1	Lysine (L-Lysine)FDA Link 01/2017
1	arseniteIBA 01/2016
1	Protons (Proton)IBA 01/2016
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	ArsenicIBA 01/2016
1	Pyruvic Acid (Pyruvate)IBA 01/2016
1	Carnitine (L-Carnitine)FDA LinkGeneric 09/2015
1	acylcarnitineIBA 09/2015
1	glutaryl-coenzyme A (glutaryl-CoA)IBA 04/2014
1	glutaric acidIBA 04/2014
1	Amino Acids FDA Link 01/2014
1	SugarsIBA 02/2013
1	Stearoyl-CoA DesaturaseIBA 10/2011
1	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2011

Therapy/Procedure

8	Therapeutics 04/2024 - 01/2014
2	Caloric Restriction 02/2013 - 08/2011
1	Drug Therapy (Chemotherapy) 04/2024
1	Aftercare (After-Treatment) 01/2021