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Burkhard Hinz Selected Research

Neoplasms (Cancer)

1/2024β-Caryophyllene Inhibits Endothelial Tube Formation by Modulating the Secretome of Hypoxic Lung Cancer Cells-Possible Role of VEGF Downregulation.
1/2023Inhibition of Monoacylglycerol Lipase Decreases Angiogenic Features of Endothelial Cells via Release of Tissue Inhibitor of Metalloproteinase-1 from Lung Cancer Cells.
1/2023Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells.
7/2022Effective tumor cell abrogation via Venetoclax-mediated BCL-2 inhibition in KMT2A-rearranged acute B-lymphoblastic leukemia.
6/2022The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins.
5/2022A Sensitive LC-MS/MS Method for the Simultaneous Determination of Two Thia-Analogous Indirubin N-Glycosides and Indirubin-3'-Monoxime in Plasma and Cell Culture Medium.
4/2022Validation of an LC-MS/MS Method for the Quantification of the CK2 Inhibitor Silmitasertib (CX-4945) in Human Plasma.
3/2022Impact of Cannabinoid Compounds on Skin Cancer.
1/2022PEGylation increases antitumoral activity of arginine deiminase of Streptococcus pyogenes.
1/2022Implementation of a combined CDK inhibition and arginine-deprivation approach to target arginine-auxotrophic glioblastoma multiforme cells.
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Burkhard Hinz Research Topics

Disease

34Neoplasms (Cancer)
01/2024 - 01/2006
17Lung Neoplasms (Lung Cancer)
01/2024 - 04/2010
7Neoplasm Metastasis (Metastasis)
01/2022 - 04/2010
6Pain (Aches)
01/2012 - 02/2002
5Inflammation (Inflammations)
01/2023 - 09/2004
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2023 - 04/2021
4Melanoma (Melanoma, Malignant)
10/2023 - 04/2010
4Carcinoma (Carcinomatosis)
03/2016 - 01/2008
3Skin Neoplasms (Skin Cancer)
06/2023 - 03/2022
3Glioblastoma (Glioblastoma Multiforme)
06/2022 - 01/2022
3Uterine Cervical Neoplasms (Cancer of the Cervix)
04/2010 - 01/2008
3Open-Angle Glaucoma (Glaucoma, Open Angle)
03/2006 - 11/2005
2Hypoxia (Hypoxemia)
01/2024 - 01/2023
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
07/2022 - 03/2020
2Thrombosis (Thrombus)
11/2016 - 01/2016
2Migraine Disorders (Migraine)
11/2015 - 11/2015
2Osteoarthritis
01/2012 - 09/2004
2Rheumatoid Arthritis
01/2005 - 06/2003
1Atherosclerotic Plaque (Atheroma)
11/2023
1Pre-Eclampsia (Preeclampsia)
01/2023
1Fetal Growth Retardation (Intrauterine Growth Retardation)
01/2023
1Premature Birth (Birth, Premature)
01/2023
1Dermatomyositis (Dermatopolymyositis)
12/2022
1Dermatitis
12/2022
1Atopic Dermatitis (Atopic Eczema)
12/2022
1Pruritus (Itching)
12/2022
1Leg Ulcer
12/2022
1Alopecia (Baldness)
12/2022
1Skin Diseases (Skin Disease)
12/2022
1Systemic Scleroderma (Systemic Sclerosis)
12/2022
1Psoriasis (Pustulosis Palmaris et Plantaris)
12/2022
1Hematologic Neoplasms (Hematological Malignancy)
07/2022
1Multiple Sclerosis
06/2022
1Leukemia
05/2022
1Mitochondrial Diseases (Mitochondrial Disease)
01/2022
1Chronic Disease (Chronic Diseases)
04/2021

Drug/Important Bio-Agent (IBA)

24CannabinoidsIBA
01/2023 - 12/2004
13EndocannabinoidsIBA
01/2023 - 02/2009
8Tissue Inhibitor of Metalloproteinase-1IBA
01/2023 - 01/2008
7CannabidiolIBA
06/2022 - 04/2010
7Cyclooxygenase 2 (Cyclooxygenase-2)IBA
03/2016 - 09/2004
6EnzymesIBA
01/2019 - 02/2002
6Small Interfering RNA (siRNA)IBA
09/2018 - 01/2008
5Conditioned Culture MediaIBA
01/2024 - 09/2014
4indirubinIBA
10/2023 - 04/2010
4Anticarcinogenic AgentsIBA
01/2023 - 01/2008
4Proteins (Proteins, Gene)FDA Link
07/2022 - 11/2013
4ProstaglandinsIBA
03/2016 - 02/2002
4Acetaminophen (Paracetamol)FDA LinkGeneric
11/2015 - 02/2009
3GlycosidesIBA
10/2023 - 04/2010
3JZL 184IBA
01/2023 - 01/2021
3Monoacylglycerol LipasesIBA
01/2023 - 01/2019
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2023 - 02/2009
3Dronabinol (THC)FDA LinkGeneric
06/2022 - 01/2008
3Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2019 - 01/2013
3anandamide (arachidonylethanolamide)IBA
11/2016 - 12/2004
3Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
11/2015 - 04/2012
3Celecoxib (Celebrex)FDA Link
11/2015 - 12/2004
3Analgesics (Analgesic Drugs)IBA
11/2015 - 02/2002
3Cannabinoid Receptors (Cannabinoid Receptor)IBA
11/2014 - 01/2008
3methanandamideIBA
09/2014 - 01/2008
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
11/2013 - 12/2004
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2024 - 01/2023
22-oxindole (oxindole)IBA
10/2023 - 05/2022
2silmitasertibIBA
04/2022 - 03/2020
2arginine deiminaseIBA
01/2022 - 01/2022
2Arginine (L-Arginine)FDA Link
01/2022 - 01/2022
2fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
01/2019 - 03/2016
2Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA
11/2015 - 11/2014
2Ibuprofen (Motrin)FDA LinkGeneric
11/2015 - 09/2011
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
11/2015 - 02/2002
22-chloro-5-nitrobenzanilideIBA
11/2013 - 01/2013
2Mitogen-Activated Protein KinasesIBA
04/2012 - 01/2008
2matrigelIBA
04/2010 - 01/2008
1caryophylleneIBA
01/2024
1Transcription Factors (Transcription Factor)IBA
01/2024
1CC ChemokinesIBA
11/2023
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
11/2023
1LigandsIBA
11/2023
1ChromonesIBA
06/2023
1Histones (Histone)IBA
06/2023
1glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA
01/2023
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2023
1venetoclaxIBA
07/2022
1nabiximols (Sativex)IBA
06/2022
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
04/2022
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2022
1p38 Mitogen-Activated Protein KinasesIBA
06/2021
1Thromboplastin (Tissue Factor)IBA
06/2021
1AM 251 (AM251)IBA
01/2021
1CB1 Cannabinoid Receptor (CB1 Receptor)IBA
01/2021
1Adenosine Triphosphate (ATP)IBA
03/2020
1Casein Kinase II (Casein Kinase 2)IBA
03/2020
1Complement System Proteins (Complement)IBA
01/2019
1Fatty Acid-Binding ProteinsIBA
01/2019

Therapy/Procedure

12Therapeutics
06/2023 - 01/2008
2Chinese Traditional Medicine (Traditional Chinese Medicine)
05/2022 - 04/2021
2Self Medication
11/2015 - 11/2015
1Photochemotherapy (Photodynamic Therapy)
06/2023
1Palliative Care (Palliative Therapy)
03/2022