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Joshua Gustine Selected Research

Waldenstrom Macroglobulinemia (Macroglobulinemia)

1/2021Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia.
1/2018MYD88 wild-type Waldenstrom Macroglobulinaemia: differential diagnosis, risk of histological transformation, and overall survival.
1/2018Ibrutinib Monotherapy in Symptomatic, Treatment-Naïve Patients With Waldenström Macroglobulinemia.
1/2018BTKCys481Ser drives ibrutinib resistance via ERK1/2 and protects BTKwild-type MYD88-mutated cells by a paracrine mechanism.
5/2017Prospective, Multicenter Clinical Trial of Everolimus as Primary Therapy in Waldenstrom Macroglobulinemia (WMCTG 09-214).
1/2017Acquired mutations associated with ibrutinib resistance in Waldenström macroglobulinemia.

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Joshua Gustine Research Topics

Disease

6Waldenstrom Macroglobulinemia (Macroglobulinemia)
01/2021 - 01/2017
3Lymphoma (Lymphomas)
01/2022 - 11/2016
2Bone Marrow Diseases (Bone Marrow Disease)
01/2021 - 05/2017
2Disease Progression
01/2018 - 01/2017
2Neoplasms (Cancer)
01/2018 - 01/2018
1Immunoglobulin Light-chain Amyloidosis
01/2022
1Cardiac Arrhythmias (Arrythmia)
01/2021
1Multiple Myeloma
01/2018
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2018
1Thrombotic Microangiopathies
11/2016
1Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
11/2016
1Amyloidosis
11/2016
1Membranous Glomerulonephritis (Membranous Nephropathy)
11/2016

Drug/Important Bio-Agent (IBA)

5ibrutinibIBA
01/2021 - 01/2017
4Immunoglobulin M (IgM)IBA
01/2021 - 11/2016
2Hemoglobins (Hemoglobin)IBA
01/2021 - 05/2017
1pro-brain natriuretic peptide (1-76)IBA
01/2022
1A 419259IBA
01/2022
1daratumumabIBA
01/2022
1src-Family KinasesIBA
01/2022
1Interleukin-6 (Interleukin 6)IBA
01/2018
1Interleukin-10 (Interleukin 10)IBA
01/2018
1EverolimusFDA Link
05/2017

Therapy/Procedure

3Therapeutics
01/2022 - 05/2017
1Duration of Therapy
01/2022
1Drug Therapy (Chemotherapy)
01/2022